This volume comprises refereed papers and abstracts of the 8th International Conference on the Evolution of Language (EVOLANG8), held in Utrecht on 1417 April 2010. As the leading international conference in the field, the biennial EVOLANG meeting is characterized by an invigorating, multidisciplinary approach to the origins and evolution of human language, and brings together researchers from many subject areas, including anthropology, archaeology, biology, cognitive science, computer science, genetics, linguistics, neuroscience, palaeontology, primatology and psychology. The latest theoretical, experimental and modelling research on language evolution is presented in this collection, including contributions from many leading scientists in the field.
Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.
The Science of Starving in Victorian Literature, Medicine, and Political Economy is a reassessment of the languages and methodologies used, throughout the nineteenth century, for discussing extreme hunger in Britain. Set against the providentialism of conservative political economy, this study uncovers an emerging, dynamic way of describing literal starvation in medicine and physiology. No longer seen as a divine punishment for individual failings, starvation became, in the human sciences, a pathology whose horrific symptoms registered failings of state and statute. Providing new and historically-rich readings of the works of Charles Kingsley, Elizabeth Gaskell, and Charles Dickens, this book suggests that the realism we have come to associate with Victorian social problem fiction learned a vast amount from the empirical, materialist objectives of the medical sciences and that, within the mechanics of these intersections, we find important re-examinations of how we might think about this ongoing humanitarian issue.
The past 25 years has seen the emergence of a wealth of data suggesting that novel biological functions of known proteins play important roles in biology and medicine. This ability of proteins to exhibit more than one unique biological activity is known as protein moonlighting. Moonlighting proteins can exhibit novel biological functions, thus extending the function of the proteome, and are also implicated in the pathology of a growing number of idiopathic and infectious diseases. This book, written by a cell biologist, protein evolutionary biologist and protein bioinformatician, brings together the latest information on the structure, evolution and biological function of the growing numbers of moonlighting proteins that have been identified, and their roles in human health and disease. This information is revealing the enormous importance protein moonlighting plays in the maintenance of human health and in the induction of disease pathology. Protein Moonlighting in Biology and Medicine will be of interest to a general readership in the biological and biomedical research community.
The A-Z of Plastic Surgery is a comprehensive and easily digestible manual to plastic surgery. Written in an encyclopaedic format, the concise style aims to provide a rapid and structured summary of each topic and allows for each to be grasped quickly and succinctly in either a clinical or exam revision setting. The new edition has been fully revised and updated by a team of experienced plastic surgeons and successful FRCS (Plast) candidates, to provide a quick reference guide to learning topics and concepts in the field of plastic surgery. Particularly relevant to plastic surgery trainees, it will also be of value to the specialist as a reference text and to health professionals in allied specialties.
Full biographical accounts of the members of St John's College Oxford give much new evidence for academic life of the period. This volume comprises a register of all who were academically of St John's College, Oxford, from its foundation in 1555 until 1660, as well as of a number of men otherwise associated with it. It includes many figures of nationalimportance, among them William Laud, William Juxon, Edmund Campion, and Bulstrode Whitelocke, scholarly translators of the Bible, five future earls, and many Members of Parliament. The biographies, based on a very wide rangeof sources, amplify and correct existing work and identify many previously unknown St John's men. The introduction draws on this new research to provide a richer and more nuanced portrayal of an early-modern Oxford college than any so far attempted - and, since the College was both a Catholic Marian foundation and the institution in which Laud spend much of his life, makes a significant contribution to an understanding of the ramifications of early modernEnglish religious loyalties. The College's involvement in early academic drama in Oxford also receives special attention, as do its many Shakespearean connections (both family and Warwickshire affinity). An extensive Glossary provides essential supplementary guidance to the workings of the early-modern academic world. Andrew Hegarty gained his D.Phil. from the University of Oxford; his research is on the history of European universities in theearly modern period.
This volume provides a tutorial review and evaluation of scientific research on the accuracy and reliability of eyewitness identification. The book starts with the perspective that there are a variety of conceptual and empirical problems with eyewitness identification as a form of forensic evidence, just as there are a variety of problems with other forms of forensic evidence. There is then an examination of the important results in the study of eyewitness memory and the implications of this research for psychological theory and for social and legal policy. The volume takes the perspective that research on eyewitness identification can be seen as the paradigmatic example of how psychological science can be successfully applied to real-world problems.
Sustainable development is a highly topical issue and is of critical importance to tourism as the environment is of utmost importance for the continued development and prosperity of the industry. There have been numerous texts written on sustainable tourism and the measures to mitigate and manage this but none which acknowledges Information and Communication Technologies (ICT) as a mechanism of doing so despite being an emerging area of research. ICT in this context refers to innovative tools which form an integrated system of software and networked equipment that facilitates data processing information sharing communication and the ability to search and select from an existing range of products and services for an organisation’s benefits. Despite the symbiotic relationship, which exists between ICT and sustainable tourism, there has been little research, which has considered how the use of such technology can be used to make sustainable tourism development a more workable reality. This opportune book is the first to provide a focus on the interrelationship of these two important topics demonstrating their synergies and providing insight into a new and innovative approach to managing sustainable tourism development. It considers the use of technology to reduce the negative impacts of tourism from both the demand and supply side perspectives. A critical review of a range of cutting edge technologies used by tourists and businesses to assess their usefulness in managing sustainable tourism development from the macro to the micro level is also discussed. It further integrates examples and practical applications to show how ICT can be an invaluable mechanism in the management of sustainable tourism development. This cutting-edge volume provides a wealth of information on an important yet neglected subject. This book will be invaluable reading for students, researchers, academics and members of the tourism industry looking for new and innovate ways of fostering a more sustainable tourism industry.
This is a classic edition of Andrew Ellis’ acclaimed introduction to the scientific study of reading, writing and dyslexia, which now includes a new introduction from the author. The book describes the remarkable skills of reading and writing – how we acquire them, how we exercise them as skilled readers and writers, and what can go wrong with them in childhood disorders or as a result of brain damage. The new introduction reflects on some key research developments since the book was first published. Reading, Writing and Dyslexia is an engaging introduction to the field which is still completely relevant to today’s readers. It will remain essential reading for all students of psychology and education, whilst also being accessible to parents and teachers.
On Optimal Interconnections for VLSI describes, from a geometric perspective, algorithms for high-performance, high-density interconnections during the global and detailed routing phases of circuit layout. First, the book addresses area minimization, with a focus on near-optimal approximation algorithms for minimum-cost Steiner routing. In addition to practical implementations of recent methods, the implications of recent results on spanning tree degree bounds and the method of Zelikovsky are discussed. Second, the book addresses delay minimization, starting with a discussion of accurate, yet algorithmically tractable, delay models. Recent minimum-delay constructions are highlighted, including provably good cost-radius tradeoffs, critical-sink routing algorithms, Elmore delay-optimal routing, graph Steiner arborescences, non-tree routing, and wiresizing. Third, the book addresses skew minimization for clock routing and prescribed-delay routing formulations. The discussion starts with early matching-based constructions and goes on to treat zero-skew routing with provably minimum wirelength, as well as planar clock routing. Finally, the book concludes with a discussion of multiple (competing) objectives, i.e., how to optimize area, delay, skew, and other objectives simultaneously. These techniques are useful when the routing instance has heterogeneous resources or is highly congested, as in FPGA routing, multi-chip packaging, and very dense layouts. Throughout the book, the emphasis is on practical algorithms and a complete self-contained development. On Optimal Interconnections for VLSI will be of use to both circuit designers (CAD tool users) as well as researchers and developers in the area of performance-driven physical design.
Prepositions: The Ultimate Book - Mastering English Prepositions - Revised Edition - A guide for developing successful speakers, Prepositions: The Ultimate Book proposes a pedagogical approach to the prepositions of the English language. Designed for all levels of students for easy comprehension and quick learning, over 2,000 examples of simple and complex (phrasal) prepositions and prepositional idioms help readers understand and create the intended message. By learning how to correctly link words to their specific meanings, students will be able to build fluency and accuracy while working with creativity and autonomy. Organized by function and subject, with over 400 prepositions and prepositional entries-including more than 100 illustrations-this book helps students identify and use context cues through a variety of examples of real-world situations. Whether you are in the English classroom or out in the professional world, Prepositions: The Ultimate Book is an indispensable and comprehensive reference tool for all international learners seeking to communicate more effectively and naturally in the English language. Andrew Bruckfield's English Language Reference Library: - Prepositions: The Ultimate Book - Mastering English Prepositions, The Key to Fluency in English Conversation - Prepositions by Example - The Quickest Way to Learn and Practice English Prepositions - Understanding the Concepts of English Prepositions - The Container Effect, Dimensional Prepositions, The Proximity Effect, The Concept of Magnitude, The Sound-Wave Effect, The Platform Effect, Complex Prepositions: including Spatial, Nonspatial & Temporal Uses - Essential & Practical English Grammar - A Compendium of Verbs, Phrasal Verbs, Idioms, Prepositions, Vocabulary, Punctuation & more.
Andrew Motion's dramatic narration of Keats's life is the first in a generation to take a fresh look at this great English Romantic poet. Unlike previous biographers, Motion pays close attention to the social and political worlds Keats inhabited. Making incisive use of the poet's inimitable letters, Motion presents a masterful account. "Motion has given us a new Keats, one who is skinned alive, a genius who wrote in a single month all the poems we cherish, a victim who was tormented by the best doctors of the age. . . . This portrait, stripped of its layers of varnish and restored to glowing colours, should last us for another generation."—Edmund White, The Observer Review "Keats's letters fairly leap off the page. . . . [Motion] listens for the 'freely associating inquiry and incomparable verve and dash,' the 'headlong charge,' of Keats's jazzlike improvisations, which give us, like no other writing in English, the actual rush of a man thinking, a mind hurtling forward unpredictably and sweeping us along."—Morris Dickstein, New York Times Book Review "Scrupulous and eloquent."—Gregory Feeley, Philadelphia Inquirer
“This international collaboration between air war historians is simply fantastic. . . . a deep-dive on the operations in a vast and very important theater of war.” —Air Classics During the final year of World War II, the defending Axis forces were steadily driven from southern skies by burgeoning Anglo-American power. This was despite the steady withdrawal of units to more demanding areas. This fifth volume of the series describes in detail the activities of the Allied tactical air forces in support of the armies on the ground as their opponents were steadily extracted from northern Italy and the Balkans for the final defense of the central European homeland. The book commences with coverage of the final fierce air-sea battles over the Aegean that preceded the advance northward to Rome and the ill-conceived British attempt to secure the Dodecanese islands following the armistice with Italy. The authors also deal fully and comprehensively with the advance northward following the occupation of Rome, and the departure of forces to support the invasion of France from the Riviera coast, coupled with the formation of a new Balkan Air Force in eastern Italy to pursue the German armies withdrawing from Yugoslavia and take possession of newly freed Greece. The effect of the creation within the same area of the US and RAF strategic forces to join the Allied Combined Bombing Offensive is also discussed. Includes photographs “Reflects the scope of a remarkable research effort and provides valuable detail that the reader is not going to find between two covers elsewhere.” —The NYMAS Review
This important book deepens our understanding of how academic libraries can better serve students' needs, and also serves as a model for other researchers interested in a user-centered approach to evaluating library services.
This book uses models of 'world literature' to present this 'quintessentially English' writer as a pioneering figure in an Anglophone Welsh literary tradition, a controversial reading that contributes to the present-day reconfiguration of cultural relations between Wales, England, Scotland
Be ready to prescribe and administer drugs safely and effectively—and grasp all the vitals of pharmacology—with the fully updated Pharmacotherapeutics for Advanced Practice, 4th edition. Written by pharmacology nursing experts, this easy-to-read text offers proven frameworks for treating more than 50 common diseases and disorders. Learn how to identify disorders, review possible therapies, then prescribe and monitor drug treatment, accurately. Based on current evidence and real-life patient scenarios, this is the perfect pharmacology learning guide and on-the-spot clinical resource. Absorb the key principles and practical methods for accurate prescribing and monitoring, with . . . NEW chapter on Parkinson’s disease, osteoarthritis, and rheumatoid arthritis NEW and updated therapies, and updated and additional case studies, with sample questions NEW content on the impacts of the Affordable Care Act Updated chapters on complementary and alternative medicine (CAM) and pharmacogenomics Updated evidence-based algorithms and drug tables – Listing uses, mechanisms, adverse effects, drug interactions, contraindications, and monitoring parameters, organized by drug class; quick access to generic and trade names and dosages Quick-scan format organizes information by body system Chapter features include: Brief overview – Pathophysiology of each disorder, and relevant classes of drugs Monitoring Patient Response section – What to monitor, and when Patient Education section – Includes information on CAM for each disorder Drug Overview tables – Usual dose, contraindications and side effects, and special considerations Algorithms – Visual cues on how to approach treatment Updated Recommended Order of Treatment tables – First-, second- and third-line drug therapies for each disorder Answers to Case Study Questions for each disorder – Strengthens critical thinking skills Selecting the Most Appropriate Agent section – The thought process for choosing an initial drug therapy Principles of Therapeutics unit – Avoiding medication errors; pharmacokinetics and pharmacodynamics; impact of drug interactions and adverse events; principles of pharmacotherapy for pediatrics, pregnancy/lactation, and geriatrics Disorders units – Pharmacotherapy for disorders in various body systems Pharmacotherapy in Health Promotion unit – Smoking cessation, immunizations, weight management Women’s Health unit – Including contraception, menopause, and osteoporosis Integrative Approach to Patient Care unit – Issues to consider when presented with more than one diagnosis Standard pharmacotherapeutics text for nurse practitioners, students, and physician assistants Ancillaries – Case Study answers, multiple choice questions and answers for every chapter, PowerPoints, Acronyms List
First published in 1999, this volume explores the issue of rural planning, which has become a complex activity in which policies in one area have important ramifications in other policy areas. It is thus very important for all those involved in rural planning affairs to remain not only up to date, but to place recent developments in a longer perspective. This new series aims to answer all these needs by providing an accurate and informed account of recent developments in North American, British and European rural policy, and critiques of policy implementation and its impacts from new material and from analyses of published research findings. This second volume in the series covers the last few years of the John Major administration until the election of the Tony Blair government in May 1997. It is divided into six chapters: overview of changes affecting all rural planning activities; the environment; town and country planning; extensive land uses; nature conservation and recreation; and social land economic issues. The next British volume will cover the entire period of the current government, with successive volumes covering each new government as it unfolds.
Countryside Planning is an in-depth and authoritative introduction to rural issues and addresses key issues such as planning for agriculture and natural environment, countryside management, forestry and the built environment.
New Clinical Genetics continues to offer the most innovative case-based approach to investigation, diagnosis, and management in genomic medicine. New Clinical Genetics is used worldwide as a textbook for medical students, but also as an essential guide to the field for genetic counselors, physician assistants, clinical and nurse geneticists, and students studying healthcare courses allied to medicine. Readers love the integrated case-based approach which ties the science to real-life clinical scenarios to really aid understanding. Clinical genetics is a fast-moving field and there have been many advances in the few years since the previous edition was published. This 4th edition has been completely updated and revised to reflect new science, new techniques and new ways of thinking. Nowhere is this more clear than in the chapter discussing genetics services which is now significantly expanded to reflect the increasing role of genomic medicine and the use of multidisciplinary teams in the management of patients with genetic disorders. The unique case-based structure and format remains the same, but substantial new material has been added to cover: polygenic risk scores – now starting to become useful clinical service tools preimplantation diagnosis noninvasive prenatal diagnosis companion diagnostics for prescribed drugs liquid biopsies in cancer epigenetics and gene regulation the widespread use of next-generation sequencing as a routine diagnostic tool the checking of a patient’s whole exome for the cause of their problem
Being able to make a correct diagnosis is one of the key aspects of every medical student's and junior doctor's clinical training. Problem-based learning is increasingly being used to focus on the causes behind the presentation of a clinical feature. The Third Edition of this best-selling book is packed full of information to help the reader move from a presenting problem to an accurate diagnosis. Covers 126 common presenting problems in both medicine and surgery in a consistent format Each topic includes a list of all common causes of the condition Key features of the various permutations are clearly discussed Includes a targeted guide to the relevant general and specific follow-up investigations which should be carried out as appropriate Now printed in colour throughout, with the relative frequency of the various conditions illustrated by colour coding, indicating common, occasional or rare causes. Important geographical variations are also highlighted Seven new chapters including rashes, thirst, and tiredness Two new sections on the differential diagnosis of biochemical and haematological disorders provide a ready check when reviewing abnormal results Each chapter ends with a key points section to highlight major aspects of the diagnosis An enlarged author team represents both medicine and surgery
Written from an archaeological perspective, Painted Caves is a beautifully illustrated introduction to the oldest art of Western Europe: the very ancient paintings found in caves. Lawson offers an up to date overview of the geographical distribution of the sites and their significance within the varied network of Palaeolithic art.
The successful FRCS Trauma and Orthopaedics Viva returns for a second edition, now including over 95 viva topics. Completely updated to include current clinical management guidelines, and exam hot topics, the book is brought to you again from the team behind the highly successful Oxford revision course. Based on the principle that viva candidates improve their technique by observing and learning from others, the editor team have created a best-practice formula for dealing with the individual scenarios. The book is set out in a simple format and every viva topic is introduced by an initial clinical photograph, radiograph, or diagram. Sets of questions follow underneath with the suggested answers on the next page. This allows the reader to work in pairs, groups, or on their own. Based on the Oxford revision course, this book is already a tried and tested revision tool, making it ideal preparation for the FRCS Trauma and Orthopaedics Viva exam.
Academic condemnation has long been recognized as an important issue in the history of universities and the history of medieval thought. Yet few studies have examined the phenomenon in serious detail. This work is the first book-length study of academic condemnations at Oxford. It explores every known case in detail, including several never examined before, and then considers the practice of condemnation as a whole. As such, it provides a context to see John Wyclif and the Oxford Lollards not as unique figures, but as targets of a practice a century old by 1377. It argues that condemnation did not happen purely for reasons of theological purity, but reflected social and institutional pressures within the university.
This classic text, now in its sixth edition, combines a thorough coverage of the basic principles of civil engineering hydraulics with a wide-ranging treatment of practical, real-world applications. It now includes a powerful online resource with worked solutions for chapter problems and solution spreadsheets for more complex problems that may be used as templates for similar issues. Hydraulics in Civil and Environmental Engineering is structured into two parts to deal with principles and more advanced topics. The first part focuses on fundamentals, such as hydrostatics, hydrodynamics, pipe and open channel flow, wave theory, physical modelling, hydrology and sediment transport. The second part illustrates engineering applications of these principles to pipeline system design, hydraulic structures, river and coastal engineering, including up-to-date environmental implications, as well as a chapter on computational modelling, illustrating the application of computational simulation techniques to modern design, in a variety of contexts. New material and additional problems for solution have been added to the chapters on hydrostatics, pipe flow and dimensional analysis. The hydrology chapter has been revised to reflect updated UK flood estimation methods, data and software. The recommendations regarding the assessment of uncertainty, climate change predictions, impacts and adaptation measures have been updated, as has the guidance on the application of computational simulation techniques to river flood modelling. Andrew Chadwick is an honorary professor of coastal engineering and the former associate director of the Marine Institute at the University of Plymouth, UK. John Morfett was the head of hydraulics research and taught at the University of Brighton, UK. Martin Borthwick is a consultant hydrologist, formerly a flood hydrology advisor at the UK’s Environment Agency, and previously an associate professor at the University of Plymouth, UK.
Technologies that electronically mediate conversation, such as text-based chat or desktop video conferencing, draw on theories of human−human interaction to make predictions about the effects of design decisions. This lecture reviews the theory that has been most influential in this area: Clark's theory of language use. The key concept in Clark's theory is that of common ground. Language is viewed as a collaborative activity that uses existing common ground to develop further common ground and, hence, to communicate efficiently. The theory (a) defines different kinds of common ground, (b) formalizes the notion of collaborative activity as a “joint action,” and (c) describes the processes by which common ground is developed through joint action. Chapter 1 explains why a purely cognitive model of communication is not enough and what is meant by the phrase “collaborative activity.” Chapter 2 introduces the idea of common ground and how it is used in language through an example of two people conversing over a video link. Chapter 3 indicates where the interested reader can find out about the antecedents to Clark's theory. Chapter 4 sets out the fundamental concepts in Clark's theory. Chapter 5 uses five published case studies of electronically mediated communication to illustrate the value of the theory. These include studies of a computer-supported meeting room (Cognoter), a video tunnel that supports gaze awareness, video conferencing in medical consultation, and text chat. Table of Contents: Motivation - Conversation as a Collaborative Activity / Overview - Developing Common Ground, An Example / Scientific Foundations / The Theory in More Detail / Case Studies - Applying the Theory to Electronically Mediated Communication / Current Status
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.