This research monograph discusses newly developed mathematical models and methods that provide biologically meaningful inferences from data on cancer latency produced by follow-up and discrete surveillance studies. Methods for designing optimal strategies of cancer surveillance are systematically presented for the first time in this book. It offers new approaches to the stochastic description of tumor latency, employs biologically-based models for making statistical inference from data on tumor recurrence and also discusses methods of statistical analysis of data resulting from discrete surveillance strategies. It also offers insight into the role of prognostic factors based on the interpretation of their effects in terms of parameters endowed with biological meaning, as well as methods for designing optimal schedules of cancer screening and surveillance. Last but not least, it discusses survival models allowing for cure rates and the choice of optimal treatment based on covariate information, and presents numerous examples of real data analysis.
Sorbent Deformation discusses the theoretical and experimental study of the deformation of solid bodies during their ad- or absorptive interaction with gases or vapours. The book is the first monograph which deals with the problem of ad- and absorbent non-inertness, compiled from a 15-year study by the author on swelling or deformed ad- and absorptive systems. The results from the study are of practical and scientific value to engineers and scientists in the areas of physical chemistry, chemical engineering and environmental control. They could also be of interest to those looking to solve problems in such areas as forecasting, technological processing and fuel drying stimulation. · Provides novel, practical information on the behaviour of the systems used in environment control · Presents the derivation of the equation describing single- and multicomponent adsorption and absorption in swelling / deformed systems· Identifies the results of direct measurements on ad-and absorbent deformations (charcoals, clay minerals, organic cation substituted clay minerals, etc.) with a new high sensitivity method
This book is designed to scrutinize the Russian business sector in transition with special attention to firm organization, business integration, corporate governance, and company management. Using a unique dataset of Russian joint-stock companies, the authors empirically analyze key issues for understanding the Russian corporate sector.
An internal account of the political activities taking place inside the Kremlin from the fall of the USSR under the administration of Gorbachev to the future of Russia under Putin"--Provided by publisher.
This is the first major re-assessment of Ivan the Terrible to be published in the West in the post-Soviet period. It breaks away from older stereotypes of the tsar – whether as ‘crazed tyrant’ and ‘evil genius’, on the one hand, or as a ‘great and wise statesman’, on the other – to provide a more balanced picture. It examines the ways in which Ivan’s policies contributed to the creation of Russia’s distinctive system of unlimited monarchical rule. Ivan is best remembered for his reign of terror, the book pays due attention to the horrors of his executions, tortures and repressions, especially in the period of the oprichnina (1565-72), when he mysteriously divided his realm into two parts, one of which was under the direct control of the tsar and his oprichniki (bodyguard). This work argues that the often gruesome forms assumed by the terror reflected not only Ivan’s personal cruelty and sadism, but also his religious views about the divinely ordained right of the tsar to punish his treasonous subjects, just as sinners were punished in Hell. Primarily chronological in its organisation, the book focuses on three main aspects of Ivan’s power: the territorial expansion of the state, the mythology, rituals and symbols of monarchy; and the development of the autocratic system of rule.
While focusing on contemporary developments of the Russian state, this book highlights those developments' roots in the historic concept of autocracy. The central scholarly question is not whether Russia will recreate a strong state, but, rather, what kind of a strong state it will be and under which circumstances it will function.
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