A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.
This study considers the maritime economy of ancient Cyprus from 1450 BC to 295 BC, combining, for the first time, three distinct disciplines, that is History, Archaeology and Economic theory. The principles of New Institutional Economics are used to trace the island’s institutions and their continuity and to reconstruct its maritime history.
No Hamlets is the first critical account of the role of Shakespeare in the intellectual tradition of the political right in Germany from the founding of the Empire in 1871 to the 'Bonn Republic' of the Cold War era. In this sustained study, Andreas Höfele begins with Friedrich Nietzsche and follows the rightist engagement with Shakespeare to the poet Stefan George and his circle, including Ernst Kantorowicz, and the literary efforts of the young Joseph Goebbels during the Weimar Republic, continuing with the Shakespeare debate in the Third Reich and its aftermath in the controversy over 'inner emigration' and concluding with Carl Schmitt's Shakespeare writings of the 1950s. Central to this enquiry is the identification of Germany and, more specifically, German intellectuals with Hamlet. The special relationship of Germany with Shakespeare found highly personal and at the same time highIy political expression in this recurring identification, and in its denial. But Hamlet is not the only Shakespearean character with strong appeal: Carl Schmitt's largely still unpublished diaries of the 1920s reveal an obsessive engagement with Othello which has never before been examined. Interest in German philosophy and political thought has increased in recent Shakespeare studies. No Hamlets brings historical depth to this international discussion. Illuminating the constellations that shaped and were shaped by specific appropriations of Shakespeare, Höfele shows how individual engagements with Shakespeare and a whole strand of Shakespeare reception were embedded in German history from the 1870s to the 1950s and eventually 1989, the year of German reunification.
Dynamical zeta functions are associated to dynamical systems with a countable set of periodic orbits. The dynamical zeta functions of the geodesic flow of lo cally symmetric spaces of rank one are known also as the generalized Selberg zeta functions. The present book is concerned with these zeta functions from a cohomological point of view. Originally, the Selberg zeta function appeared in the spectral theory of automorphic forms and were suggested by an analogy between Weil's explicit formula for the Riemann zeta function and Selberg's trace formula ([261]). The purpose of the cohomological theory is to understand the analytical properties of the zeta functions on the basis of suitable analogs of the Lefschetz fixed point formula in which periodic orbits of the geodesic flow take the place of fixed points. This approach is parallel to Weil's idea to analyze the zeta functions of pro jective algebraic varieties over finite fields on the basis of suitable versions of the Lefschetz fixed point formula. The Lefschetz formula formalism shows that the divisors of the rational Hassc-Wcil zeta functions are determined by the spectra of Frobenius operators on l-adic cohomology.
This book studies structural properties of Q-curvature from an extrinsic point of view by regarding it as a derived quantity of certain conformally covariant families of differential operators which are associated to hypersurfaces.
Does globalization erode the nation state's capacity to act? Are nation states forced to change their policies even if this goes against the democratic will of their electorates? How does government action change under conditions of globalization? Questions like these have not only featured highly in political debates in recent years, but also in academic discourse. This book seeks to contribute to that debate. The general question it addresses is whether globalization leads to policy convergence — a central, but contested topic in the debate, as theoretical arguments can be advanced both in favour of and against the likelihood of such a development. More specifically, the book contains detailed empirical case studies of four countries (the United States, the United Kingdom, Germany, and Switzerland) in a policy area where state action has been particularly challenged by the emergence of world-wide, around-the-clock financial markets in the last few decades, namely that of the regulation and supervision of the banking industry. Based on careful analysis of historical developments, specific challenges, the character of policy networks and institutions, and their interaction in the political process, this book argues that nation states still possess considerable room for manouevre in pursuing their policies. Even if they choose supranational coordination and cooperation, their national institutional configurations still function as filters in the globalization process. This book is of particular value to readers interested in the politics and policies of globalization, the interaction of business communities and the political system in different countries, and students of comparative politics interested in detailed case studies of policy-making.
The book deals with the ancient exploitation and production of copper, exemplified by the mining district of Faynan, Jordan. It is an interdisciplinary study that comprises (mining-) archaeological and scientific aspects. The development of organizational patterns and technological improvements of mining and smelting through the ages (5th millennium BC to Roman Byzantine period), in a specific mining region, is discussed.
Distinctively tying history with theory, political economist Joseph A. Schumpeter reached far back in time to understand what drives economic development and determines its course. Historical and empirical research provided a laboratory for learning. At the same time, he reached for a long-term vision through theoretical inspection and utmost abstraction, seeking to distil a phenomenon's essential nature and function. He believed that good theory can indicate where the economy is headed in the future. Schumpeter's attention to history and theory also informed the plan for this book. Part I trails the historical stream of financial innovations and the scholarly struggle to assimilate them in monetary thought, while Part II focuses on Schumpeter's own monetary theory. Its deliberate reconstruction from scattered sources reveals a strikingly original and still modern conception. Drawing from the detailed study of documents at various archives in Austria, Part III then concentrates on the business history of Schumpeter's failed personal endeavours in banking and as a proto-venture capitalist. Finally, Part IV casts light on the legacy of Schumpeter's monetary ideas on contemporary thought. It depicts how monetary theory initially left them behind, yet has more recently set out to return to his ideas on money, financial innovation, and growth. Overall, a surprisingly coherent picture emerges from the study of Schumpeter's neglected monetary theory, his personal history, and his intellectual legacy on the present day.
Evolution of Water Supply Through the Millennia presents the major achievements in the scientific fields of water supply technologies and management throughout the millennia. It provides valuable insights into ancient water supply technologies with their apparent characteristics of durability, adaptability to the environment, and sustainability. A comparison of the water technological developments in several civilizations is undertaken. These technologies are the underpinning of modern achievements in water engineering and management practices. It is the best proof that “the past is the key for the future.” Rapid technological progress in the twentieth century created a disregard for past water technologies that were considered to be far behind the present ones. There are a great deal of unresolved problems related to the management principles, such as the decentralization of the processes, the durability of the water projects, the cost effectiveness, and sustainability issues such as protection from floods and droughts. In the developing world, such problems were intensified to an unprecedented degree. Moreover, new problems have arisen such as the contamination of surface and groundwater. Naturally, intensification of unresolved problems led societies to revisit the past and to reinvestigate the successful past achievements. To their surprise, those who attempted this retrospect, based on archaeological, historical, and technical evidence were impressed by two things: the similarity of principles with present ones and the advanced level of water engineering and management practices. Evolution of Water Supply Through the Millennia is intended for engineers in water resources companies, hydraulic design companies, and water Institutes. It can be used for all courses related to water resources. Authors: Andreas N. Angelakis, Institute of Iraklion, National Foundation for Agricultural Research (N.AG.RE.F.), Greece, Larry W. Mays, School of Sustainable Engineering and the Built Environment, Arizona State University, USA, Demetris Koutsoyiannis, School of Civil Engineering, National Technical University of Athens, Greece, Nikos Manassis, School of Civil Engineering, National Technical University of Athens, Greece.
This book provides an accessible and systematic restatement of the desert model for criminal sentencing by one of its leading academic exponents. The desert model emphasises the degree of seriousness of the offender's crime in deciding the severity of his punishment, and has become increasingly influential in recent penal practice and scholarly debate. It explains why sentences should be based principally on crime-seriousness, and addresses, among other topics, how a desert-based penalty scheme can be constructed; how to gauge punishments' seriousness and penalties' severity; what weight should be given to an offender's previous convictions; how non-custodial sentences should be scaled; and what leeway there might be for taking other factors into account, such as an offender's need for treatment. The volume will be of interest to all those working in penal theory and practice, criminal sentencing and the criminal law more generally.
This work provides coverage of experimental and theoretical procedures for vapour-liquid equilibria (VLE). A survey of the different models and approaches in recent literature enables the reader to choose the appropriate action.
Laser-Beam Interactions with Materials treats, from a physicist's point of view, the wide variety of processes that lasers can induce in materials. Physical phenomena ranging from optics to shock waves are discussed, as are applications in such diverse fields as semiconductor annealing, hole drilling and fusion plasma production. The approach taken emphasizes the fundamental ideas and their interrelations. The newcomer is given the necessary important background material, while the active research worker finds a critical and comprehensive review of the field.
Organic Trace Analysis" presents the basics of trace analysis, from sample preparation to the measurement: Students are introduced to statistical evaluation, quality control technologies, sampling and preparation of organic traces, as well as to enrichment and separation of samples. Spectroscopic techniques as chromatography, capillary electrophoresis, mass spectrometry, and receptor-based bioanalysis are presented in detail.
Why have our drug wars failed and how might we turn things around? Ask the authors of this hardhitting exposè of U.S. efforts to fight drug trafficking and abuse. In a bold analysis of a century's worth of policy failure, Drug War Politics turns on its head many familiar bromides about drug politics. It demonstrates how, instead of learning from our failures, we duplicate and reinforce them in the same flawed policies. The authors examine the "politics of denial" that has led to this catastrophic predicament and propose a basis for a realistic and desperately needed solution. Domestic and foreign drug wars have consistently fallen short because they are based on a flawed model of force and punishment, the authors show. The failure of these misguided solutions has led to harsher get-tough policies, debilitating cycles of more force and punishment, and a drug problem that continues to escalate. On the foreign policy front, billions of dollars have been wasted, corruption has mushroomed, and human rights undermined in Latin America and across the globe. Yet cheap drugs still flow abundantly across our borders. At home, more money than ever is spent on law enforcement, and an unprecedented number of people—disproportionately minorities—are incarcerated. But drug abuse and addiction persist. The authors outline the political struggles that help create and sustain the current punitive approach. They probe the workings of Washington politics, demonstrating how presidential and congressional "out-toughing" tactics create a logic of escalation while the criticisms and alternatives of reformers are sidelined or silenced. Critical of both the punitive model and the legalization approach, Drug War Politics calls for a bold new public health approach, one that frames the drug problem as a public health—not a criminal—concern. The authors argue that only by situating drug issues in the context of our fundamental institutions—the family, neighborhoods, and schools—can we hope to provide viable treatment, prevention, and law enforcement. In its comprehensive investigation of our long, futile battle with drugs and its original argument for fundamental change, this book is essential for every concerned citizen.
This volume deals with the sermons of St. Maximus I, Bishop of Turin about AD 305-420. It presents an exemplary study which, besides clarifying problems of dating and authorship, points out the importance of context for an appropriate interpretation of sermon literature. The sermons are thus placed in the contexts of contemporary history, of society and of liturgy. The liturgical contextualisation forms the core of the book. The author reconstructs the liturgical year of late-Antique Turin and takes it as the basis of a detailed diachronic analysis of the bishop's preaching from advent to pentecost. Additionally, the Feasts of the Saints are seen in their kerygmatic function. In a concluding chapter the author tackles such problems as the exegetical nature of preaching and the importance of the Bible.
Micro process engineering is approaching both academia and industry. With the provision of micro devices, systems and whole plants by commercial suppliers, one main barrier for using these units has been eliminated. This book focuses on processes and their plants rather than on devices: what is 'before', 'behind' and 'around' micro device fabrication - and gives a comprehensive and detailed overview on the micro-reactor plants and three topic-class applications which are mixing, fuel processing, and catalyst screening. Thus, the book reflects the current level of development from 'micro-reactor design' to 'micro-reactor process design'.
Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies based on the targeted manipulation of trace metal homeostasis that will generate new awareness surrounding trace metal levels during pregnancy. - Reviews the role of trace metals in brain development - Summarizes research linking trace metals and autism - Explores heterogenous phenotypes as a factor of genetic and non-genetic factors - Includes animal and human stem research - Contains many useful diagrams, tables and flow charts - Proposes future therapies based on biometal homeostasis
The nervous system is particularly fascinating for many biologists because it controls animal characteristics such as movement, behavior, and coordinated thinking. Invertebrate neurobiology has traditionally been studied in specific model organisms, whilst knowledge of the broad diversity of nervous system architecture and its evolution among metazoan animals has received less attention. This is the first major reference work in the field for 50 years, bringing together many leading evolutionary neurobiologists to review the most recent research on the structure of invertebrate nervous systems and provide a comprehensive and authoritative overview for a new generation of researchers. Presented in full colour throughout, Structure and Evolution of Invertebrate Nervous Systems synthesizes and illustrates the numerous new findings that have been made possible with light and electron microscopy. These include the recent introduction of new molecular and optical techniques such as immunohistochemical staining of neuron-specific antigens and fluorescence in-situ-hybridization, combined with visualization by confocal laser scanning microscopy. New approaches to analysing the structure of the nervous system are also included such as micro-computational tomography, cryo-soft X-ray tomography, and various 3-D visualization techniques. The book follows a systematic and phylogenetic structure, covering a broad range of taxa, interspersed with chapters focusing on selected topics in nervous system functioning which are presented as research highlights and perspectives. This comprehensive reference work will be an essential companion for graduate students and researchers alike in the fields of metazoan neurobiology, morphology, zoology, phylogeny and evolution.
In this collection of essays John Fentress Gardner illuminates many challenging aspects of modern life that concern him-and concern most of us, as well. From poverty and environmental degradation to sexuality, parental discipline, and the pressures of modern life; from the further paths of knowledge to war and peace-he reveals how all these faces of life speak, and he points clearly to what they themselves ask for. In this sense, he looks directly to the future, not as a prophet, or even guide, but as one filled with wonder and hope. He looks often to Emerson; to Rudolf Steiner, the Austrian philosopher and seer; and to others. But the weight of his regard falls upon the future, particularly upon the bearers of the future: today's youth. Gardner has been a teacher of youth for many years in the Waldorf private school system. He has a deep feeling for young people-not only for their masks and attitudes of the moment, but also for their deep (generally unconscious) longings, and for what happens when these are thwarted, as they often are. In one of the most impressive essays of this book, Gardner makes it startlingly clear that peace is not a true goal or attainment if it is viewed in opposition to war and conflict. For in this opposition, conflict remains. It is the third - transcending and holding the tension between conflict and quiescent peace - in which the redeeming force is found. In climbing through the heart into the Heart of hearts, is found the spiritual, true secret of Peace. There, the longing to know finds answers.
This book successfully connects archaeology and archaeometallurgy with geoscience and metallurgy. It addresses topics concerning ore deposits, archaeological field evidence of early metal production, and basic chemical-physical principles, as well as experimental ethnographic works on a low handicraft base and artisanal metal production to help readers better understand what happened in antiquity. The book is chiefly intended for scholars and students engaged in interdisciplinary work.
Nautilus Award Gold Medal Winner, Ecology & Environment In Matter and Desire, internationally renowned biologist and philosopher Andreas Weber rewrites ecology as a tender practice of forging relationships, of yearning for connections, and of expressing these desires through our bodies. Being alive is an erotic process—constantly transforming the self through contact with others, desiring ever more life. In clever and surprising ways, Weber recognizes that love—the impulse to establish connections, to intermingle, to weave our existence poetically together with that of other beings—is a foundational principle of reality. The fact that we disregard this principle lies at the core of a global crisis of meaning that plays out in the avalanche of species loss and in our belief that the world is a dead mechanism controlled through economic efficiency. Although rooted in scientific observation, Matter and Desire becomes a tender philosophy for the Anthropocene, a “poetic materialism,” that closes the gap between mind and matter. Ultimately, Weber discovers, in order to save life on Earth—and our own meaningful existence as human beings—we must learn to love.
Money is a legal institution with principal economic and sociological consequences. Money is a debt, because that is how it is conceptualised and comes into existence: as circulating credit – if viewed from the creditor’s perspective – or, from the debtor’s viewpoint, as debt. This book presents a legal theory of money, based on the concept of dematerialised property. It describes the money creation or money supply process for cash and for bank money, and looks at modern forms of money, such as cryptocurrencies. It also shows why mainstream economics presupposes, but avoids an analysis of, money by effectively eliminating money from the microeconomic market model and declaring it as merely a neutral medium of exchange and unit of account. The book explains that money rather brings about and influences substantially the exchange or transaction it is supposed to facilitate only as a neutral medium. As the most liquid of all assets, money enables financialisation, monetisation and commodification in the economy. The central role of the banks in the money creation process and in the economy, and their strengthened position after the bank rescue measures in the wake of the financial crisis 2008-9 are also discussed. Providing a rigorous analysis of the most salient legal issues regarding money, this book will appeal to legal theorists, economists and anyone working in commercial or banking law.
The whole range of biocatalysis, from a firm grounding in theoretical concepts to in-depth coverage of practical applications and future perspectives. The book not only covers reactions, products and processes with and from biological catalysts, but also the process of designing and improving such biocatalysts. One unique feature is that the fields of chemistry, biology and bioengineering receive equal attention, thus addressing practitioners and students from all three areas.
In 1986 the first research study investigating Acceptance and Commitment Therapy (ACT) was published. It aimed to determine if an early conceptualization of the ACT model could be used to treat depression. Since this seminal study, further investigations have been conducted across every imaginable psychological issue and the rate at which this research has emerged is impressive. This book describes the research journey that ACT has taken in the past 30 years. It also suggests, in light of the progress that has already been made, how ACT research should move forward in the coming decades.
This volume entails a collection of new ideas, themes and questions towards a phenomenon which we are used to refer to with the key term “diversity”. The aim of the book is to offer a cultural sciences perspective on “diversity”, to advance knowledge about it and enrich the dialogue between academics and practitioners in related domains of action. Today, changes in the demographic structures of the population, the migration flux, multiculturalism, the rising awareness concerning minorities’ rights, gender studies and so on lead to a complex picture of what “diversity” means. The narrative of a society and of most organizations is constituted by multiple layers of social categorization, segregation and identity. Therefore, “diversity” defies simple definition. The contributions in this volume approach the phenomenon from different angles and reveal new theoretical, methodological and practical perspectives on it.
Die Meister der Betonschalen Mitte des 20. Jahrhunderts begann die Hochphase des Betonschalenbaus. Weltweit entstanden technisch avancierte Konstruktionen von aufsehenerregender Expressivität. Mit Félix Candela, Heinz Isler und Ulrich Müther nimmt dieses Buch exemplarisch drei Protagonisten dieser Bauweise in den Blick. Ihr Wirken – vorwiegend in Mexiko, der Schweiz und der DDR – fand unter sehr verschiedenen politischen, ökonomisch-sozialen und kulturellen Bedingungen statt. Die Autoren analysieren die Bauten und Projekte vor dem Hintergrund der Entwicklungen der Architektur und des Ingenieurwesens jener Zeit. Sie thematisieren wechselseitige Einflüsse, Gemeinsamkeiten wie Unterschiede in den Entwurfsprozessen, der Konstruktion und der Ausführung. Darüber hinaus werden Fragen der Rezeption und der heutigen Nutzung behandelt. Lernen von Félix Candela (1910–1997), Heinz Isler (1926–2009) und Ulrich Müther (1934–2007) und ihren historischen Schalenbauten Unbekanntes aus den Planarchiven Englisch mit Zusammenfassungen auf Deutsch und Spanisch
Eine junge Filmemacherin kann einen Künstler, der so gut zu ihr passen würde, nicht lieben, da sie ihr Geschick ausschließlich von den Sternen lenken lässt. Beim Zahnarzt gerät ein Patient wegen eines Tierfilms in Rage. Ein bosnischer Nachwuchsrapper ergeht sich in krassen Liebesschwüren. Auf einer Matratze liegt eine junge Frau und ein Mann kommt sie jeden Abend besuchen – doch etwas in dieser Geschichte mutet unheimlich an. Ein Patient versucht, seinen Analytiker in der Wahnsinn zu treiben. Und der Tagesablauf eines Einsamen wird nur am Sonntag unterbrochen, wenn er sich unter die Wartenden in der Ankunftshalle des Münchner Flughafens mischt. In seinen elf Kurzgeschichten gestattet uns Andreas Keck zynische, bissige, verstörende aber mitunter auch vergnügliche Blicke auf die Neurosen hinter den asphaltierten und gepflegten Fassaden urbanisierter Zweibeiner. Edition Periplaneta: Belletristik, Romane, Erzählungen Die Romane, Kurzgeschichten oder klassischen Novellen dieser Edition erscheinen unter der Maxime, dass die Erzählungen einem literarischen Anspruch folgen, aber trotzdem unterhaltsam sind. Und so sind die hier veröffentlichten Werke witzig, philosophisch, gesellschaftskritisch, erhellend, melancholisch und/oder skurril - und dies manchmal in den seltsamsten Kombinationen. Die Edition Periplaneta ist eine der Editionen des Periplaneta Verlag Berlin.
Am 16. September 2000 hat Ernst Hagemann sein 70. Lebensjahr vollendet. Aus Anlaß dieses Tages und in Dankbarkeit für sein Engagement der Gründung und Erhaltung des Iserlohn-Kreises sowie der Anerkennung seines Lebenswerkes im Bereich der China-Forschung widmen ihm Freunde und Kollegen im Iserlohn-Kreis sowie Kollegen des DIW die vorliegende Festschrift. Ernst Hagemann war seit 1963 Mitarbeiter im DIW. Insbesondere rekonstruierte er dort die Außenhandelsstatistik der VR China, welche bis dahin nicht verfügbar war und ein Novum in der deutschen Chinaforschung darstellte. In den 1980er und 1990er Jahren trat zunehmend die Transformationsforschung in den Vordergrund seiner wissenschaftlichen Tätigkeit. Seit seinem Ausscheiden aus dem DIW im Jahr 1996 ist Ernst Hagemann weiterhin als Berater für internationale Organisationen und Unternehmen aktiv.Will man über China empirisch arbeiten, ist eine gründliche Analyse des zu Grunde liegenden statistischen Materials erforderlich. Die Beiträge von Margot Schüller "Getting the numbers right - Deficiencies in China's statistical system", von Doris Fischer "What's in a number? The role of statistics in China's contemporary economic research and economic policies", von Björn Alpermann "Die chinesische Umweltstatistik: Eine materialkritische Einführung" sowie von Bettina Gransow "Counting China's Floating Population: A Gendered Perspective" gehen den wichtigen Fragen des Umgangs mit chinesischen Originaldaten nach. Globalisierung und Entwicklung zeigen sich in China an einer Fülle von Beispielen. Christian von Hirschhausen und Michael Andres untersuchen diese Frage in ihrem Beitrag "Long-term electricity demand in China - From quantitative to qualitative growth?" in bezug auf die Elektrizitätswirtschaft, Andreas Oberheitmann in seinem Artikel "WTO and the Kyoto process - possible effects on China's energy policy and trade" hinsichtlich der internationalen Klimaverhandlungen, der Energiepolitik und des Handels Chinas. InhaltsverzeichnisInhalt: M. Schüller, Getting the numbers right: deficiencies in China's statistical system - D. Fischer, What's in a number? The role of statistics in China's contemporary economic research and economic policies - B. Alpermann, Die chinesische Umweltstatistik: Eine materialkritische Einführung - B. Gransow, Counting China's floating population: A gendered perspective - C. von Hirschhausen / M. Andres, Long-term electricity demand in China: from quantitative to qualitative growth? - A. Oberheitmann, WTO and the Kyoto process: possible effects on China's energy policy and trade
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