Covering every problem encountered in today’s intensive care unit, this leading critical care textbook presents the knowledge and expertise of more than 350 global experts in this fast-changing field. Beginning with the social aspects of medicine, it then discusses monitoring and organ system pathobiology followed by specific diseases states/syndromes. Each chapter begins with immediate concerns and proceeds to broader-based discussions of relevant pathophysiologic and clinical issues.
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
In this work we plan to revise the main techniques for enumeration algorithms and to show four examples of enumeration algorithms that can be applied to efficiently deal with some biological problems modelled by using biological networks: enumerating central and peripheral nodes of a network, enumerating stories, enumerating paths or cycles, and enumerating bubbles. Notice that the corresponding computational problems we define are of more general interest and our results hold in the case of arbitrary graphs. Enumerating all the most and less central vertices in a network according to their eccentricity is an example of an enumeration problem whose solutions are polynomial and can be listed in polynomial time, very often in linear or almost linear time in practice. Enumerating stories, i.e. all maximal directed acyclic subgraphs of a graph G whose sources and targets belong to a predefined subset of the vertices, is on the other hand an example of an enumeration problem with an exponential number of solutions, that can be solved by using a non trivial brute-force approach. Given a metabolic network, each individual story should explain how some interesting metabolites are derived from some others through a chain of reactions, by keeping all alternative pathways between sources and targets. Enumerating cycles or paths in an undirected graph, such as a protein-protein interaction undirected network, is an example of an enumeration problem in which all the solutions can be listed through an optimal algorithm, i.e. the time required to list all the solutions is dominated by the time to read the graph plus the time required to print all of them. By extending this result to directed graphs, it would be possible to deal more efficiently with feedback loops and signed paths analysis in signed or interaction directed graphs, such as gene regulatory networks. Finally, enumerating mouths or bubbles with a source s in a directed graph, that is enumerating all the two vertex-disjoint directed paths between the source s and all the possible targets, is an example of an enumeration problem in which all the solutions can be listed through a linear delay algorithm, meaning that the delay between any two consecutive solutions is linear, by turning the problem into a constrained cycle enumeration problem. Such patterns, in a de Bruijn graph representation of the reads obtained by sequencing, are related to polymorphisms in DNA- or RNA-seq data.
Learn how to gather detailed statistics and data with this one-stop, comprehensive course along with hands-on recipes to get your infrastructure up and running with Zabbix. About This Book Monitor your network and deploy impressive business solutions with Zabbix Get practical recipes to automate your Zabbix infrastructure and create impressive graphs Integrate, customize, and extend your monitoring solutions with external components and software. Who This Book Is For This course is for System Administrators who have been managing and monitoring infrastructure. You do not need any knowledge about Zabbix. What You Will Learn Efficiently collect data from a large variety of monitoring objects Organize your data in graphs, charts, maps, and slide shows Write your own custom probes and monitoring scripts to extend Zabbix Configure Zabbix and its database to be high available and fault-tolerant Automate repetitive procedures using Zabbix's API FInd out how to monitor SNMP devices Manage hosts, users, and permissions while acting upon monitored conditions Set up your Zabbix infrastructure efficiently Customize the Zabbix interface to suit your system needs Monitor your VMware infrastructure in a quick and easy way with Zabbix In Detail Nowadays, monitoring systems play a crucial role in any IT environment. They are extensively used to not only measure your system's performance, but also to forecast capacity issues. This is where Zabbix, one of the most popular monitoring solutions for networks and applications, comes into the picture. With an efficient monitoring system in place, you'll be able to foresee when your infrastructure runs under capacity and react accordingly. Due to the critical role a monitoring system plays, it is fundamental to implement it in the best way from its initial setup. This avoids misleading, confusing, or, even worse, false alarms that can disrupt an efficient and healthy IT department. This course is for administrators who are looking for an end-to-end monitoring solution. It will get you accustomed with the powerful monitoring solution, starting with installation and explaining the fundamentals of Zabbix. Moving on, we explore the complex functionalities of Zabbix in the form of enticing recipes. These recipes will help you to gain control of your infrastructure. You will be able to organize your data in the form of graphs and charts along with building intelligent triggers for monitoring your network proactively. Toward the end, you will gain expertise in monitoring your networks and applications using Zabbix. This Learning Path combines some of the best that Packt has to offer in one complete, curated package. It includes content from the following Packt products: Zabbix Network Monitoring-Second Edition Zabbix Cookbook Mastering Zabbix-Second Edition Style and approach This course is a compact practical guide that starts from the fundamentals of Zabbix and takes you all the way to building a monitoring solution that gathers data from a large variety of systems. Along the way, we will discuss the low-level operational details that should benefit you even if you have used Zabbix for a while. It also follows a step-by-step approach that is easy to follow, full of engaging examples, and will help you apply the theory to practice.
The economic liberalization in India over the last three decades has provided a wealth of opportunity for entrepreneurs looking to start and expand their businesses. Since the economy opened up in the 1990s, entrepreneurial activity in the private sector has been largely responsible for the strong economic growth experienced in the country. India is presently the world’s third largest source of start-ups, and was ranked the second most entrepreneurial country in the world in the recent Global Entrepreneurship Monitor (GEM) report, ahead of large economic powerhouses such as the United States, China and the UK. Entrepreneurship in India looks at the dynamic and changing nature of entrepreneurship in India. The book examines the history of entrepreneurship in India, different entrepreneurship models adopted, the entrepreneurial ecosystem and looks at the future of entrepreneurship in the country. This book will benefit businesspeople, policy makers and researchers looking to understand more about entrepreneurship in India, and offers guidance to foreign businesses looking to engage with entrepreneurs in India.
This book illustrates the clinical interface between neurology and psychiatry by focusing on neuropsychiatric conditions characterised by alterations at the level of both motor function and behaviour. The neuropsychiatric approach to movement disorders and epilepsy is of key importance in clinically assessing and treating these common and often disabling conditions. While addressing the clinical challenges posed by the behavioural aspects of movement disorders and epilepsy, it invites readers on a journey through the evolving discipline of neuropsychiatry / behavioural neurology – both in the past and today. This discipline has an illustrious history, and continues its ascending trajectory in the new millennium through the activity of long-established national organisations (British Neuropsychiatry Association, BNPA, and American Neuropsychiatric Association, ANPA) as well as newly developed strategic research initiatives (Michael Trimble Neuropsychiatry Research Group, MTNRG).
The first practical, user-friendly guide to the theory and practice of a routinely used technique, this new manual provides the specialist in training with a thorough grounding in the equipment, procedures, and clinical findings with which clinicians need to be familiar. Conceived as an alternative to the large and expensive texts aimed at specialists, the handbook is divided into two sections, which present: a review of the main kinds of arrhythmia, with illustrations of typical ECG findings supported where appropriate by correlative imaging the principal diagnostic and therapeutic procedures, including implantation of pacemakers, resynchronization therapy, use and placement of catheters and ablation techniques Providing practical guidance on clinical applications, and illustrated with numerous graphics, checklists and flowcharts to enable readers to locate information quickly and easily, Handbook of Cardiac Electrophysiology is an accessible resource covering a widespread, but complex technology.
The definitive guide to genetic bone disorders, now revised and expanded with glossy photographs and radiographs "Brilliantly written and produced and deserves to be on the shelves of all pediatric radiologists. It should also be available to geneticists, counselors, and pediatricians." --Radiology This updated and expanded fourth edition of Bone Dysplasias presents age-related radiographs, photographs and clinical guidelines for more than 250 rare constitutional skeletal diseases. Focusing on diagnostically essential imaging and clinical features, each chapter is supplemented with prognostic and therapeutic information, a guide to differential diagnoses, and a short list of the most relevant publications. Organized in accordance with the most recent International Nosology and Classification of Genetic Skeletal Disorders, this new Bone Dysplasias distills the insights of a small, world-class author team on diagnosis and clinical approaches to this most difficult class of disorders.
Based on the 4th edition of the renowned textbook of the same name, this softcover manual focuses on the information necessary to make clinical decisions in the ICU. It begins with a crucial section on responding to emergency situations in the ICU. It proceeds to cover the most relevant clinical infomation in all areas of critical care including critical care monitoring, techniques and procedures, essential physiologic concers, shock states, pharmacology, surgical critical care, and infectious diseases. The manual also contains thorough reviews of diseaes by organ system: cardiovascular diseases, repiratory disorders, neurologic and gastrointestinal disorders, renal, endocrine, skin and muscle diseases, and hematologic/ oncologic diseases. This essential new resource is written in an easy-to-read style that makes heavy use of bulleted lists and tables and features an all-new full color format with a color art program. All critical care providers will find this a useful clinical resource.
This is an illustrated version (replete with black and white pictures and graphs) of Dr. Andrea Diem-Lane's book, Darwin's DNA, which has been republished in a smaller paperback version entitled The DNA of Consciousness. Explores evolutionary theory and how Darwinian natural selection can help explain why consciousness developed as a virtual simulator over time. Fully illustrated.
An introduction to game theory that offers not only theoretical tools but also the intuition and behavioral insights to apply these tools to real-world situations. This introductory text on game theory provides students with both the theoretical tools to analyze situations through the logic of game theory and the intuition and behavioral insights to apply these tools to real-world situations. It is unique among game theory texts in offering a clear, formal introduction to standard game theory while incorporating evidence from experimental data and introducing recent behavioral models. Students will not only learn about incentives, how to represent situations as games, and what agents “should” do in these situations, but they will also be presented with evidence that either confirms the theoretical assumptions or suggests a way in which the theory might be updated. Features: Each chapter begins with a motivating example that can be run as an experiment and ends with a discussion of the behavior in the example. Parts I–IV cover the fundamental “nuts and bolts” of any introductory game theory course, including the theory of games, simple games with simultaneous decision making by players, sequential move games, and incomplete information in simultaneous and sequential move games. Parts V–VII apply the tools developed in previous sections to bargaining, cooperative game theory, market design, social dilemmas, and social choice and voting. Part VIII offers a more in-depth discussion of behavioral game theory models including evolutionary and psychological game theory. Supplemental material on the book’s website include solutions to end-of-chapter exercises, a manual for running each chapter’s experimental games using pencil and paper, and the oTree codes for running the games online.
Magic and antimagic labelings are among the oldest labeling schemes in graph theory. This book takes readers on a journey through these labelings, from early beginnings with magic squares up to the latest results and beyond. Starting from the very basics, the book offers a detailed account of all magic and antimagic type labelings of undirected graphs. Long-standing problems are surveyed and presented along with recent results in classical labelings. In addition, the book covers an assortment of variations on the labeling theme, all in one self-contained monograph. Assuming only basic familiarity with graphs, this book, complete with carefully written proofs of most results, is an ideal introduction to graph labeling for students learning the subject. More than 150 open problems and conjectures make it an invaluable guide for postgraduate and early career researchers, as well as an excellent reference for established graph theorists.
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