Today, well over 100 commercial antibiotics are available to treat everything from minor nuisances to life-threatening infections, but their indiscriminate use for nonbacterial ailments and agriculture has led to a disturbing trend of antibiotic resistance. Researchers are hard at work searching for new approaches to treat bacterial illnesses in an effort to preserve modern life as we know it. Antibacterials covers the topics relevant to entering this field of study. We discuss basic bacterial biology and the roles that bacteria play in the world. We also cover the history of antibacterials, both ancient and modern, as well as how commercial antibiotics work on a biochemical level. We examine the interplay between resistance, tolerance, and virulence, the threat that they pose, and ways that scientists are thinking about addressing them. Finally, we provide an overview of the antibacterial development process from initial lead discovery to clinical trials and commercialization.
Today, well over 100 commercial antibiotics are available to treat everything from minor nuisances to life-threatening infections, but their indiscriminate use for nonbacterial ailments and agriculture has led to a disturbing trend of antibiotic resistance. Researchers are hard at work searching for new approaches to treat bacterial illnesses in an effort to preserve modern life as we know it. Antibacterials covers the topics relevant to entering this field of study. We discuss basic bacterial biology and the roles that bacteria play in the world. We also cover the history of antibacterials, both ancient and modern, as well as how commercial antibiotics work on a biochemical level. We examine the interplay between resistance, tolerance, and virulence, the threat that they pose, and ways that scientists are thinking about addressing them. Finally, we provide an overview of the antibacterial development process from initial lead discovery to clinical trials and commercialization.
In The Politics of Taste Ana María Reyes examines the works of Colombian artist Beatriz González and Argentine-born art critic, Marta Traba, who championed González's art during Colombia's National Front coalition government (1958–74). During this critical period in Latin American art, artistic practice, art criticism, and institutional objectives came into strenuous yet productive tension. While González’s triumphant debut excited critics who wanted to cast Colombian art as modern, sophisticated, and universal, her turn to urban lowbrow culture proved deeply unsettling. Traba praised González's cursi (tacky) recycling aesthetic as daringly subversive and her strategic localism as resistant to U.S. cultural imperialism. Reyes reads González's and Traba's complex visual and textual production and their intertwined careers against Cold War modernization programs that were deeply embedded in the elite's fear of the masses and designed to avert Cuban-inspired revolution. In so doing, Reyes provides fresh insights into Colombia's social anxieties and frustrations while highlighting how interrogations of taste became vital expressions of the growing discontent with the Colombian state.
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