This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.
This book presents up-to-date information on the general principles of diagnostic and therapeutic nuclear medicine in the context of endocrinology. The content is divided into six parts. Section I examines general aspects of radiopharmaceuticals, scintigraphy, single-photon emission computed tomography (SPECT), positron emission tomography (PET), radionuclide therapies and radioguided surgery. Section II discusses diagnostic applications in benign thyroid diseases and evaluation of thyroid nodules. Section III gives an overview of the management of parathyroid diseases. Section IV presents diagnostic techniques in well-differentiated thyroid cancer. Section V addresses procedures and therapy in adrenal benign and malignant disorders (phaechromocytomas and paragangliomas). Lastly, the diagnosis and treatment of neuroendocrine tumors are featured in Section VI. Nuclear Medicine in Endocrine Disorders: Diagnosis and Therapy is intended for non-specialists in nuclear medicine working in the field of endocrinology, and is also a valuable resource for researchers and students.
Composer, pianist, editor, writer, and pedagogue Mario Lavista (1943-2021) was a central figure of the cultural and artistic scene in Mexico and one of the leading Ibero-American composers of his generation. His music is often described as evocative and poetic, noted for his meticulous attention to timbre and motivic permutation, and his creative trajectory was characterized by its intersections with the other arts, particularly poetry and painting. Understanding analysis as an affective practice, this study explores the intertextual connections between the multiple texts-musical or otherwise-that are present in Lavista's music. It argues that, through adopting an interdisciplinary and transhistorical approach to music composition, Lavista forged a cosmopolitan imaginary to challenge imposed stereotypes of what Mexican music should sound like. This imaginary becomes a strategy of resistance against imperialist agendas placed upon postcolonial peripheries. Departing from traditional biographical and chronological frameworks that exalt masters and masterworks, this book offers a nuanced, personal narrative informed by conversations with composers, performers, artists, choreographers, poets, writers, and filmmakers. Implementing an innovative mosaic of methodologies, from archival work, to musical and intertextual analysis, oral history, and (auto)ethnography, this book is the first to offer a contextual framing of Lavista's career within a panoramic view of contemporary music practices in Mexico during the past fifty years"--
Quantifying exergy losses in the energy supply system of buildings reveals the potential for energy improvement, which cannot be discovered using conventional energy analysis. Thermoeconomics combines economic and thermodynamic analysis by applying the concept of cost (an economic concept) to exergy, as exergy is a thermodynamic property fit for this purpose, in that it combines the quantity of energy with its quality factor. Exergy Analysis and Thermoeconomics of Buildings applies exergy analysis methods and thermoeconomics to the built environment. The mechanisms of heat transfer throughout the envelope of buildings are analyzed from an exergy perspective and then to the building thermal installations, analyzing the different components, such as condensing boilers, absorption refrigerators, microcogeneration plants, etc., including solar installations and finally the thermal facilities as a whole. A detailed analysis of the cost formation process is presented, which has its physical roots firmly planted in the second law of thermodynamics. The basic principles and the rules of cost allocation, in energy units (exergy cost), in monetary units (exergoeconomic cost), and in CO2 emissions (exergoenvironmental cost), based on the so-called Exergy Cost Theory are presented and applied to thermal installations of buildings. Clear and rigorous in its exposition, Exergy Analysis and Thermoeconomics of Buildings discusses exergy analysis and thermoeconomics and the role they could play in the analysis and design of building components, either the envelope or the thermal facilities, as well as the diagnosis of thermal installations. This book moves progressively from introducing the basic concepts to applying them. Exergy Analysis and Thermoeconomics of Buildings provides examples of specific cases throughout this book. These cases include real data, so that the results obtained are useful to interpret the inefficiencies and losses that truly occur in actual installations; hence, the assessment of their effects encourages the manner to improve efficiency. - Applies exergy analysis methods for the installation of building thermal facilities equipment components, including pipes, valves, heat exchangers, boilers and heat pumps - Helps readers determine the operational costs of heating and cooling building systems - Includes exergy analysis methods that are devoted to absorption refrigerators, adsorption cooling systems, basic air conditioning processes, ventilation systems and solar systems, either thermal and PV - Discusses the direct application of exergy analysis concepts, including examples of buildings with typical heating, DHW and air conditioning installations
This issue of Sleep Medicine Clinics is edited by Dr. Ana Krieger and focuses on the Social and Economic Dimensions of Sleep Disorders. Article topics include: Sleep in the Aging Population; OSA screening in Atrial Fibrillation and Other Arrhythmias; Early Identification and Management of Narcolepsy; Hypersomnia; Legal and Regulatory Aspects of Sleep Disorders; Peri-Operative Screening Sleep Apnea; Management of Sleep Apnea Syndromes in Heart Failure; Sleep and Society; Pediatric Sleep Disturbances; Behavioral Strategies for Managing Insomnia and Stress; The Socio-Economic Impact of Managing Hypoventilation during Sleep; and The Impact of Portable Sleep Testing.
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