Published in 1995, this set of 13 essays on the causes and implications of financial problems in three different economic organizations - corporate, semi-co-operative and non-co-operative farming communities and sovereign states. Areas covered include insolvency and bankruptcy, and risk-sharing/spreading behaviour.
Why property law needs globalization strategies -- Local to global : an institutional analysis -- Land -- Tangible goods, monetary claims, investment securities -- Intellectual property, data, and digital assets -- Security interests and proprietary priorities in insolvency
Discussing more than 120 full-length plays, this volume provides an overview of the most important and memorable theatrical works of crime and detection produced between 1950 and 1975.
A story is a living thing. And you don't work on a living thing, you work with it. This is the way of the screenwriter, and it is something that writer and director Amnon Buchbinder believes all masterful screenwriters understand intuitively: learning how to work with story through a painstaking process of trial, error, and self exploration. Amnon Buchbinder draws on his knowledge as a teacher and his experience as a script doctor and a story editor to explore this creative process. Along the way he illustrates principles often inspired by the philosophy of Laozi (Lao Tze) with examples drawn from major motion pictures such as Memento and The Piano. For the beginning or seasoned screenwriter who aspires to more than mere competence, Buchbinder illuminates a path towards mastery of the craft. For the lover of the cinematic experience, he opens a curtain to reveal a rarely seen world behind the big screen.
Professor Yoseph (Joe) Imry, an early initiator of mesoscopic physics, has been among the leaders in this field for several decades. This book contains articles by leading (theoretical and experimental) scientists working in nanoscience and in related fields. Most of the contributions, consisting both reviews of the state of the art and new results, summarize invited talks given at two conferences held in honor of Imry's 70th birthday: the 101st Statistical Mechanics Conference (Rutgers University, May 10?12, 2009), and Perspectives of Mesoscopic Physics (Weizmann Institute of Science, May 31?June 1, 2009). This book covers a broad range of active research in nanoscience, including topics like quantum interference, decoherence, electron correlations, nano superconductors and nano magnets, nonequilibrium and glassy behavior.
Discussing more than 80 full-length plays, this volume provides an overview of the most important and memorable theatrical works of crime and detection produced between 1975 and 2000. Each entry includes a plot synopsis, production data, and the opinions of well-known and respected critics and scholars.
In this volume, Amnon Kabatchnik provides an overview of more than 150 important and memorable theatrical works of crime and detection between 1925 and 1950. Each entry includes a plot synopsis, production data, and the opinions of well known and respected critics and scholars.
There have been remarkably few systematic expositions of the theory of derived categories since its inception in the work of Grothendieck and Verdier in the 1960s. This book is the first in-depth treatment of this important component of homological algebra. It carefully explains the foundations in detail before moving on to key applications in commutative and noncommutative algebra, many otherwise unavailable outside of research articles. These include commutative and noncommutative dualizing complexes, perfect DG modules, and tilting DG bimodules. Written with graduate students in mind, the emphasis here is on explicit constructions (with many examples and exercises) as opposed to axiomatics, with the goal of demystifying this difficult subject. Beyond serving as a thorough introduction for students, it will serve as an important reference for researchers in algebra, geometry and mathematical physics.
Members of the protein kinase C (PKC) family of Ser/Thr kinases are encoded by nine distinct but closely related genes, which give rise to more than 12 different protein isoforms via a mechanism of alternative RNA splicing. Most PKC proteins are ubiquitously expressed and participate in a plethora of functions in most cell types. A majority of PKC isoforms is also expressed in cells of the immune system in which they are involved in signal transduction downstream of a range of surface receptors, including the antigen receptors on T and B lymphocytes. PKC proteins are central to signal initiation and propagation, and to the regulation of processes leading to immune cell proliferation, differentiation, homing and survival. As a result, PKC proteins directly impact on the quality and quantity of immune responses and indirectly on the host resistance to pathogens and tendency to develop immune deficiencies and autoimmune diseases. A significant progress was made in recent years in understanding the regulation of PKC enzymes, their mechanism of action and their role in determining immunocyte behavior This volume reviews the most significant contributions made in the field of immune cell regulation by PKC enzymes. Several manuscripts are devoted to the role of distinct PKC isoforms in the regulation of selected immunocyte responses. Additional manuscripts review more general mechanisms of regulation of PKC enzymes, either by post-translational modifications, such as phosphorylation or controlled proteolysis, or by interaction with different binding proteins that may alter the conformation, activity and subcellular location of PKC. Both types of mechanisms can introduce conformational changes in the molecule, which may affect its ability to interact with cofactors, ATP, or substrates. This topic will be followed by a discussion on the positive and negative impact of individual PKC isoforms on cell cycle regulation. A second section of this volume concentrates on selected topics relevant to role of the novel PKC isoform, PKC-theta, in T lymphocyte function. PKC-theta plays important and some non-redundant roles in T cell activation and is a key isoform that recruits to the immunological synapse - the surface membrane area in T cells that comes in direct contact with antigen presenting cells. The immunological synapse is formed in T cells within seconds following the engagement of the TCR by a peptide-bound MHC molecule on the surface of antigen-presenting cells. It serves as a platform for receptors, adaptor proteins, and effector molecules, which assemble into multimolecular activation complexes required for signal transduction. The unique ability of PKC-theta to activate the NF-kB, AP-1 and NF-AT transcription factors is well established, and recent studies contributed essential information on the mechanisms involved in the recruitment of PKC-theta to the center of the immunological synapse and the nature of its substrates and the role of their phosphorylated forms in signal transduction. Additional review manuscripts will describe the unique behavior of PKC-theta in regulatory T cells and its role in the regulation of other cell populations, including those of the innate immune response. This volume brings together leading experts from different disciplines that review the most recent discoveries and offer new perspectives on the contributions of PKC isoforms to biochemical processes and signaling events in different immune cell populations and their impact on the overall host immune response.
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