Dementia is a massive and increasing global problem, with the current prevalence anticipated to double every 20 years as people live longer. Neuroimaging in dementia is recommended by most clinical guidelines and its role has traditionally been to exclude a mass lesion, rather than to support a specific diagnosis. All radiologists will be aware of a steady rise in the number of requests for brain imaging in old people, but what can imaging reliably tell us and what kind of imaging should we use? In affluent societies we now have a range of structural and molecular brain imaging techniques at our disposal, with specific ligands and sophisticated image analysis techniques now available for clinical use. However, we have difficulty justifying which patients to scan, using which modality and when. We know that Alzheimer's disease is the most common neuropathology contributing to a diagnosis of Alzheimer's disease but we also know from large post-mortem studies that most brain pathology in those who have died with a diagnosis of dementia is mixed. Thus understanding different diseases that can cause dementia, how these co-exist or interact and appreciating that not all dementia is Alzheimer's disease is important. Equally important is awareness of individual differences in response to a neuropathological burden and what factors provide resilience against dementia that might be maximized to reduce or postpone its impact. This issue draws together contributions from experts in their fields to provide clarity to the topic in a comprehensive collection of articles.
Hometown Pasadena is a new breed of city guide, an in-depth, personality-rich, four-color book written by locals for locals. The five co-authors Colleen Dunn Bates, Jill Ganon, Sandy Gillis, Mel Malmberg and Mary Jane Horton are all longtime San Gabriel Valley residents, and the foreword authors are Larry Mantle (from NPR's KPCC) and Larry Wilson (editor of the Pasadena Star-News). The book is rich in history, arts, culture, restaurants, gardens, architecture, children's activities, sports and much more, and it is filled with interviews with people who make a difference in the community. It is written and designed with wit, style and intelligence. Hometown Pasadena became an immediate success, going into its fourth printing in less than one year. 256 pages, four-color throughout, flexibound binding with flaps, extensive photography and color maps
This book asks why that is. What is it about communication, as a human social and cognitive practice, that makes it so difficult to manage the disruptions caused by dementia? Why is it so common to feel awkward, confused or irritated when talking with a person living with a dementia? Why is the experience of living with a dementia so personally and socially devastating? What approaches to communication would work best, and why?"--
In the summer of 1999, Donna Dees-Thomases was busy juggling the demands of two young children and a TV job promoting comedy gags. But one day she learned about a shooting, and in the space of just a few hours, everything in Donna's life changed. . . . She decided to round up mothers--a group even more formidable than the gun lobby--to show Congress that mothers care about the gun-violence epidemic in America. She called her as-yet-unborn movement the MILLION MOM MARCH, even though she was, at the time, launching a revolution of one. In an astonishingly short 9 months, on Mother's Day 2000, Donna fulfilled her mission--and made history--when she was joined by nearly a million other mothers, fathers, grandparents, aunts, uncles, and friends who were determined to let our government know that the time for enacting sensible gun laws is now. Not even the great marches of the Civil Rights movement drew as many people as the MILLION MOM MARCH. How did one mother get the attention of our government-and the world? Looking for a Few Good Moms shows how we all can make a difference if we are willing to take a stand.
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