This book is aimed at a large audience: from students, who have a high school background in physics, mathematics, chemistry, and biology, to scien tists working in the fields of biophysics and biochemistry. The main aim of this book is to attempt to describe, in terms of physical chemistry and chemi cal physics, the peculiar features of "machines" having molecular dimen sions which play a crucial role in the most important biological processes, viz., energy transduction and enzyme catalysis. One of the purposes of this book is to analyze the physical background of the high efficiency of molecu lar machines functioning in the living cell. This book begins with a brief review of the subject (Chapter 1). Macro molecular energy-transducing complexes operate with thermal, chemical, and mechanical energy, therefore the appropriate framework to discuss the functioning of biopolymers comes from thermodynamics and chemical kinet ics. That is why we start our analysis with a consideration of the conventional approaches of thermodynamics and classical chemical kinetics, and their application to the description of bioenergetic processes (Chapter 2). Critical analysis of these approaches has led us to the conclusion that the conven tional approaches of physical chemistry to the description of the functioning of individual macromolecular devices, in many cases, appear to be incom plete. This prompted us to consider the general principles ofliving machinery from another point of view.
In 1941, Russian-born British journalist Alexander Werth observed the unfolding of the Soviet-German conflict with his own eyes. What followed was the widely acclaimed book, Russia at War, first printed in 1964. At once a history of facts, a collection of interviews, and a document of the human condition, Russia at War is a stunning, modern classic that chronicles the savagery and struggles on Russian soil during the most incredible military conflict in modern history. As a behind-the-scenes eyewitness to the pivotal, shattering events as they occurred, Werth chronicles with vivid detail the hardships of everyday citizens, massive military operations, and the political movements toward diplomacy as the world tried to reckon with what they had created. Despite its sheer historical scope, Werth tells the story of a country at war in startlingly human terms, drawing from his daily interviews and conversations with generals, soldiers, peasants, and other working class civilians. The result is a unique and expansive work with immeasurable breadth and depth, built on lucid and engaging prose, that captures every aspect of a terrible moment in human history. Now newly updated with a foreword by Soviet historian Nicolas Werth, the son of Alexander Werth, this new edition of Russia at War continues to be indispensable World War II journalism and the definitive historical authority on the Soviet-German war.
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