To the layman, all printing types look the same. But for typographers, graphic artists and others of that lunatic fringe who believe that the letters we look at daily (and take entirely for granted) are of profound importance, the question of how letters are formed, what shape they assume, and how they have evolved remains one of passionate and continuing concern. Lawson explores the vast territory of types, their development and uses, their antecedents and offspring, with precision, insight, and clarity. Written for the layman but containing exhaustive research, drawings and synopses of typefaces, this book is an essential addition to the library of anyone s typographic library. It is, as Lawson states, not written for the printer convinced that there are already too many typefaces, but rather for that curious part of the population that believes the opposite; that the subtleties of refinement as applies to roman and cursive letters have yet to be fully investigated and that the production of the perfect typeface remains a goal to be as much desired by present as by future type designers. Anyone aspiring to typographic wisdom should own and treasure this classic."--Amazon description.
14th IFIP/IEEE International Workshop on Distributed Systems: Operations and Management, DSOM 2003, Heidelberg, Germany, October 20-22, 2003, Proceedings
14th IFIP/IEEE International Workshop on Distributed Systems: Operations and Management, DSOM 2003, Heidelberg, Germany, October 20-22, 2003, Proceedings
This book constitutes the refereed proceedings of the 14th IFIP/IEEE International Workshop on Distributed Systems: Operations and Management, DSOM 2003, held in Heidelberg, Germany in October 2002. The 20 revised full papers and 6 revised short papers presented together with a keynote paper were carefully reviewed and selected from a total of 105 submissions. The papers are organized in topical sections on self-configuration, peer-to-peer management, self-optimization and performance management, utility management, self-protection and access control, manageability and instrumentation, and context-awareness.
Storage Systems: Organization, Performance, Coding, Reliability and Their Data Processing was motivated by the 1988 Redundant Array of Inexpensive/Independent Disks proposal to replace large form factor mainframe disks with an array of commodity disks. Disk loads are balanced by striping data into strips—with one strip per disk— and storage reliability is enhanced via replication or erasure coding, which at best dedicates k strips per stripe to tolerate k disk failures. Flash memories have resulted in a paradigm shift with Solid State Drives (SSDs) replacing Hard Disk Drives (HDDs) for high performance applications. RAID and Flash have resulted in the emergence of new storage companies, namely EMC, NetApp, SanDisk, and Purestorage, and a multibillion-dollar storage market. Key new conferences and publications are reviewed in this book.The goal of the book is to expose students, researchers, and IT professionals to the more important developments in storage systems, while covering the evolution of storage technologies, traditional and novel databases, and novel sources of data. We describe several prototypes: FAWN at CMU, RAMCloud at Stanford, and Lightstore at MIT; Oracle's Exadata, AWS' Aurora, Alibaba's PolarDB, Fungible Data Center; and author's paper designs for cloud storage, namely heterogeneous disk arrays and hierarchical RAID. - Surveys storage technologies and lists sources of data: measurements, text, audio, images, and video - Familiarizes with paradigms to improve performance: caching, prefetching, log-structured file systems, and merge-trees (LSMs) - Describes RAID organizations and analyzes their performance and reliability - Conserves storage via data compression, deduplication, compaction, and secures data via encryption - Specifies implications of storage technologies on performance and power consumption - Exemplifies database parallelism for big data, analytics, deep learning via multicore CPUs, GPUs, FPGAs, and ASICs, e.g., Google's Tensor Processing Units
Integrated analysis of tissue histology with the genome-wide array and clinical data has the potential to generate hypotheses as well as be prognostic. However, due to the inherent technical and biological variations, automated analysis of whole mount tissue sections is impeded in very large datasets, such as The Cancer Genome Atlas (TCGA), where tissue sections are collected from different laboratories. We aim to characterize tumor architecture from hematoxylin and eosin (H&E) stained tissue sections, through the delineation of nuclear regions on a cell-by-cell basis. Such a representation can then be utilized to derive intrinsic morphometric subtypes across a large cohort for prediction and molecular association. Our approach has been validated on manually annotated samples, and then applied to a Glioblastoma Multiforme (GBM) cohort of 377 whole slide images from 146 patients. Further bioinformatics analysis, based on the multidimensional representation of the nuclear features and their organization, has identified (i) statistically significant morphometric sub types; (ii) whether each subtype can be predictive or not; and (iii) that the molecular correlates of predictive subtypes are consistent with the literature. The net result is the realization of the concept of pathway pathology through analysis of a large cohort of whole slide images.
This important publication provides, for the first time, a comprehensive review of knowledge of reproductive seasonality in teleosts. It addresses why a particular species should show such seasonality, and how environmental cues act as regulators to ensure that reproductive maturation and breeding occur at the optimum time. The book considers the ultimate factors responsible for the evolution of reproductive seasonality in fish. It reviews salient concepts of reproductive seasonality in mammals. This volume also includes a review of accumulated knowledge of the control mechanisms of salmonids, gasterosteids, temperate cyprinids, cyprinodonts and other brackish-water forms, and marine and tropical freshwater teleosts. This is a work of value to research scientists in the field of environmental physiology, reproductive biology, and comparative neuroendocrinology and endocrinology. In addition, it is relevant for institutions involved with aquaculture and fisheries management. It is useful for post-graduate as well as undergraduate courses in fish biology and various related subjects.
Simian Virology is the first text to comprehensively cover all currently known simian viruses. Chapters provide an overview of nonhuman primate models of medically important viral diseases as well as natural infections of nonhuman primates with human and animal viruses. The text covers a variety of topics including primate models of medically important viral diseases such as AIDS, hypotheses on the origins of epidemic forms of HIV, and viral diseases caused by non-simian viruses in both wild and captive primates.
The Spine: Medical and Surgical Conditions is a complete, two volume, evidence based study edited by an internationally recognised team of spine surgeons based in the USA, China, Canada, Germany, Japan, Brazil, Egypt and India. The two volumes are divided into 137 chapters, across fourteen sections. The first section covers general topics in spinal medicine, including anatomy, biomechanics, physical and neurological examination, interventional diagnostics and therapeutics, and anaesthesia. This is followed by sections on the development of the spine, metabolic disorders, and bone grafting. Subsequent sections focus on surgery for particular parts of the spine, including cervical, lumbar and thoracic, as well as sections on spinal cord injuries and motor preservation. Later sections in the book provide information on the spine in paediatrics, adult deformity, tumours, vascular malformations and infections, complications of spinal surgery, and a final section on minimally invasive techniques. Enhanced by 1500 full colour images, The Spine: Medical and Surgical Conditions is also made available online, complete with text, images and video, with each physical copy. Key Points Comprehensive, two volume guide to spinal medicine Covers anatomy, biomechanics, examination, diagnostics, therapeutics, anaesthesia, surgery and complications Enhanced by 1500 full colour images Includes access to online version with complete text, images and video
While Karl Barth is one of the most significant theologians of the twentieth century, his contribution to ethics is less well known and subject to controversy among interpreters. Barth combined his commitment to the church and its particular task in faith and theology with a concern for ethics and politics in wider society. By examining the historical development of Barth’s ethics, this study traces the vital influences and considerable shifts in Barth’s understanding of the ethical task, situating him within his political context. Alexander Massmann provides a comprehensive explication and assessment of the full scope of Barth’s ethics, from the first edition of the Romans commentary to the final volume of the Church Dogmatics. General questions of Barth’s methodology in ethics and case studies in applied ethics are both analyzed in their intricate connection to his dogmatic thought. The study highlights how an ethical approach emerged in which the freedom of the gospel allows for considerable openness to empirical insights from other disciplines. The author reevaluates Barth’s ethics in a constructive vision of the role of the church in the quest for a just society.
Exploring the conditions under which children, as a function of their own abuse, become abusive themselves. That experiences from childhood affect our behavior in adulthood, especially in the ways we treat our children and intimate partners, is generally accepted. Indeed, theories of intergenerational transmission of violence indicate that if we ourselves have been abused and neglected as children, we will likely be abusive and neglectful to others close to us—thus extending the cycle across generations. However, many individuals who were maltreated as children do not replicate this cycle, and such models make little sense of the individual raised in a “good family” who is violent either as a child or as an adult. These discontinuities of cycles of violence and trauma have challenged professionals and nonprofessionals alike. However, broadening our vision and attending to new areas of research can help to illuminate this conundrum and open up new avenues of intervention. In this book, Pamela Alexander does just that. She proposes that an increased risk for abusive behavior or revictimization, as a function of one’s own experiences of abuse or trauma in childhood, can best be understood through the complementary lenses of attachment theory (focusing on the relationship between the child and the caregiver) and family systems theory (focusing on the larger context of this relationship). That is, what a child acquires from her relationship with a caregiver is not simply a reflection of what she has “learned” from experiencing or witnessing abuse. Rather, it emerges from the child’s felt experience of the relationship itself—on implicit emotional, physical, and neurobiological levels. Alexander founds the book on this multifaceted parent–child attachment relationship and its place in the wider family system, integrating clinical experience with close attention to the long-term neurobiological and epigenetic effects of trauma. She focuses on common outcomes of a history of maltreatment, and of child sexual abuse in particular, including peer victimization, partner violence, parenting problems, and sexual offending. A detailed review of the literature accompanies instructive case examples. Sources of trauma from outside the family, including combat exposure, political terrorism, foster care, and incarceration of parents are considered. Finally, Alexander analyzes the multiple sources of natural resilience—the neurobiological, the individual, the relational, and the social—to enable professionals of all backgrounds to tailor-make effective interventions for interrupting cycles of trauma and violence.
A comprehensive review of the arbitration law and practice in the Czech Republic including: discussion of arbitration practice and procedure; an examination of the jurisdiction of the arbitral tribunal; the appointment of arbitrators including the challenge and replacement of arbitrators; an analysis of the various types of awards including a discussion on deliberations, agreements, settlements, and the costs of arbitration; a discussion on the amendment and challenge of awards including the liability of arbitrators; and, a review of the enforcement of domestic and foreign arbitration awards.
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