In recent times, there has been a tremendous increase in our knowledge and understanding of the molecular mechanisms, genetic and epigenetic interactions, and epidemiological and aetiopathogenic factors involved in the development, progression and metastatic spread of head and neck cancers (HNCs). Improvements in diagnostics and imaging techniques, advancements in various treatment modalities, and incorporation of quality-of-life and functional outcomes in HNCs have also significantly influenced the management and outcomes of the disease. This book brings together a broad, comprehensive and balanced view of current approaches to the multidisciplinary management and underlying biology of HNCs. It covers a wide range of exciting new findings in both the clinical and the basic sciences relevant to HNC. International experts in surgical, medical and radiation oncology and the basic sciences have contributed authoritative overviews of the current status and new frontiers in the management of HNCs. The multidisciplinary scope of this book provides the necessary grounding for residents, otolaryngologists and head and neck surgeons, medical and radiation oncologists and allied specialists involved in the management of HNCs.
Self-Organised Schools: Educational Leadership and Innovative Learning Environments describes the results of the research we carried out at fourteen Italian schools that highlight how there is a positive correlation between the capabilities of school self-organization and the innovativeness of learning environments: in other words, the more self-organized schools are, the more innovative learning environments are. The results of this work are part of the strand of research of bottom-up emergency and self-organization, an extremely fruitful trend as shown by Sugata Mitra, the founder of the Self-Organized Learning Environments, according to whom, education is a self-organized system where learning is an emerging phenomenon. This book gives new insights on self-organization studies, and most of all, to the idea that change - organizational and educational innovation - sparks from the bottom. This book is aimed specifically at school principals of all levels, scholastic reformers, educational scholars, organisation and management consultants who want to innovate learning and management of learning. These actors will benefit drawing useful examples from more than thirty different learning environments worldwide, fourteen examples of schools that self-organize, two frameworks - and two ready-to-use questionnaires - measuring the innovativeness of a learning environment, and the capability of a school to self-organize. Self-organization is the most fascinating future of innovative principals
The new, therapeutically-focused Botulinum Toxin presents comprehensive, cross-disciplinary guidance on current practices, covering more than 100 non-cosmetic conditions that occur in neurology, physical medicine and rehabilitation, pain medicine, ophthalmology, gastroenterology, urology, orthopedics, and surgery. International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. With discussions of the latest in approved treatment practices as well as new and emerging uses, you’ll get in-depth management guidance on the application of the toxin. Provides clinical applications of botulinum toxin for over 100 disorders for immediate access and easy reference during practice and treatment. Covers a broad array of hot topics, including botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing. Focuses on approved uses with expert advice on thoroughly tested applications but also discusses new and emerging applications to expose you to additional treatment options. Presents the most comprehensive and up-to-date material available so you get all the information you need from this one resource. Offers the cross-disciplinary guidance of the best world-class expertise through an authoritative, international group of authors who demonstrate the applications of botulinum toxin across various specialties.
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