During the past three decades, the sugar moiety of complex carbohydrates has been found to be involved in important interactions of immunological specificity of antigens and to participate in a variety of cellular functions. The long polysaccharide side chains of the lipopolysaccharides on the outer membrane of Gram negative organisms provide surface antigens for differential serodiagnosis. Bacterial surface lectins are important in mediating the attachment of bacteria to host cells in the of infectious diseases. The carbohydrate pathogenesis moieties of cell surface glycoconjugates (glycoproteins and glycolipids) of mammals are the sites for intercellular recognition and for the regulatory molecular interactions such as interaction of complex carbohydrate with hormones or hepatic lectins. The carbohydrate side chains of many complex carbohydrates play essential roles as antigenic determinants b of human blood group ABH, Lea, Le , I, and i activities, as the Forssman specific determinant, and as tumor associated antigenic determinants. Prompted by these and other advances in the field, a Symposium on Molecular Immunology of Complex Carbohydrates was organized as a satellite meeting of the 8th International Glycoconjugate Conference held on September 8- 13, 1985, in Houston, Texas, U. S . A. Many eminent scientists contributed their knowledge at this meeting. The lecture and poster materials of the symposium are contained in this proceeding book, which is divided into four Sections and one Appendix. Section I is entitled Antibody Specificity, Epitope, and Lectinology. Dr. Elvin A.
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F. E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts. - Deepen your grasp of the physiological principles that underlie visual acuity, color vision, ocular circulation, the extraocular muscle, and much more. - Improve your understanding of physiology by referring to this totally updated volume--organized by function, rather than anatomy--and make a stronger connection between physiological principles and clinical practice. - Better visualize information with a new, revamped format that includes 1,000 illustrations presented in full-color to better clarify complex concepts and functions. - Access the most recent molecular, genetic, and biochemical discoveries affecting eye function, and gain fresh perspectives from a new, international editorial team. - Search the entire contents online and download all the illustrations at www.expertconsult.com.
This volume is volume entirely dedicated to microfabricated cell-based systems. It will provide readers with a quick introduction to the field as well as with a variety of specific examples of such Lab-on-Chip systems for cellomics applications. It will give investigators inspiration for innovative research topics, whereas end users will be surprised about the wide variety of new and exciting applications.
This comprehensive and insightful book discusses ESD protection circuit design problems from an IC designer's perspective. On-Chip ESD Protection for Integrated Circuits: An IC Design Perspective provides both fundamental and advanced materials needed by a circuit designer for designing ESD protection circuits, including: Testing models and standards adopted by U.S. Department of Defense, EIA/JEDEC, ESD Association, Automotive Electronics Council, International Electrotechnical Commission, etc. ESD failure analysis, protection devices, and protection of sub-circuits Whole-chip ESD protection and ESD-to-circuit interactions Advanced low-parasitic compact ESD protection structures for RF and mixed-signal IC's Mixed-mode ESD simulation-design methodologies for design prediction ESD-to-circuit interactions, and more! Many real world ESD protection circuit design examples are provided. The book can be used as a reference book for working IC designers and as a textbook for students in the IC design field.
Hangzhou, the capital of Zhejiang Province, and the surrounding environs have one of the richest Buddhist cultures in China. In A Tale of Two Stūpas, Albert Welter tells the story of Hangzhou Buddhism through the conceptions, erections, and resurrections of Yongming Stupa, dedicated to the memory of one of Hangzhou's leading Buddhist figures, and Leifeng Pagoda, built to house stupa relics of the historical Buddha. Welter delves into the intricacies of these two sites and pays particular attention to their origins and rebirths. These sites have suffered devastation and endured long periods of neglect, yet both have been resurrected and re-resurrected during their histories and have resumed meaningful places in the contemporary Hangzhou landscape, a mark of their power and endurance. A Tale of Two Stūpas adopts a site-specific, regional approach in order to show how the dynamics of initial conception, resurrection, and re-resurrection work, and what that might tell us about the nature of Hangzhou and Chinese Buddhism.
Written for educators seeking to engage students in collaboration and communication about authentic scenarios, The Power of Role-Based e-Learning offers helpful, accessible advice on the practice and research needed to design online role play. Drawing on the experiences of world-leading practitioners and citing an array of worldwide examples, it is a readable, non-technical, and comprehensive guide to the design, implementation, and evaluation of this exciting teaching approach. Issues discussed include: designing effective online role plays defining games, simulations and role plays moderating engaging and authentic role-based e-learning activities assessment and evaluation. The Power of Role-Based e-Learning offers a careful analysis of the strengths and learning opportunities of online role play, and is realistic about possible difficulties. Providing guidance for both newcomers and experienced professionals who are developing their online teaching repertoire, it is an invaluable resource for teachers, trainers, academics, and educational support staff involved in e-learning.
The high morbidity and mortality due to gynecologic cancer calls for much-needed efforts to provide an early diagnosis. Using novel approaches and concepts applied to the precursors of gynecological malignancies and their early carcinogenesis, the clinical-pathologic correlations of the disease are highlighted in this book.Presented in a concise manner, the book stands out from existing publications in its description of histopathological changes of the female genital tract that precede the development of cancer. It also describes the updated clinical and biological correlations of gynecologic cancer, as well as the early and often silent stages of the cancer. In addition, essential data from the literature on recent scientific progress in the field of gynecologic cancer is discussed, including original research work carried out by the authors.
The 500th anniversary of the Reformation in 2017 focuses the mind on the history and significance of Protestant forms of Christianity. It also prompts the question of how the Reformation has been commemorated on past anniversary occasions. In an effort to examine various meanings attributed to Protestantism, this book recounts and analyzes major commemorative occasions, including the famous posting of the 95 Theses in 1517 or the birth and death dates of Martin Luther, respectively 1483 and 1546. Beginning with the first centennial jubilee in 1617, Remembering the Reformation: An Inquiry into the Meanings of Protestantism makes its way to the 500th anniversary of Martin Luther's birth, internationally marked in 1983. While the book focuses on German-speaking lands, Thomas Albert Howard also looks at Reformation commemorations in other countries, notably in the United States. The central argument is that past commemorations have been heavily shaped by their historical moment, exhibiting confessional, liberal, nationalist, militaristic, Marxist, and ecumenical motifs, among others.
The entire scope of the BioMEMS field-at your fingertipsHelping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabr
This book introduces state-of-the-art experimental and numerical methods and examples for evaluating the drilling performance of engineering and biological materials, particularly in thermal aspects. The authors use a common pathway to present the technological and analytical methods for both industry (metal) drilling and orthopaedic surgery (bone) drilling research, making this book a resource for both industrial and clinical readers who wish to understand the evolution of technologies, techniques and challenges in drilling. The authors also focus on advanced engineering materials, such as titanium alloys and high-strength cast irons, which have broad applications in the automotive, aerospace, medical device and sports industries. This book is a must-read for a broad audience, including engineering students in upper-level undergraduate and graduate courses that involve machining processes; for surgery residents, fellows, and practicing surgeons; and for engineers in the medical device industry who develop new bone cutting tools. Bridges the knowledge on drilling from the manufacturing industry to healthcare; Covers the experimental and modeling aspects of drilling thermal analysis; Includes experimental studies that contain parameters and data that emulate practical production and clinical drilling.
This study starts with the basic theory of topological groups, harmonic analysis, and unitary representations. It then concentrates on geometric structure, harmonic analysis, and unitary representation theory in commutative spaces.
Initially the theory of convergence in law of stochastic processes was developed quite independently from the theory of martingales, semimartingales and stochastic integrals. Apart from a few exceptions essentially concerning diffusion processes, it is only recently that the relation between the two theories has been thoroughly studied. The authors of this Grundlehren volume, two of the international leaders in the field, propose a systematic exposition of convergence in law for stochastic processes, from the point of view of semimartingale theory, with emphasis on results that are useful for mathematical theory and mathematical statistics. This leads them to develop in detail some particularly useful parts of the general theory of stochastic processes, such as martingale problems, and absolute continuity or contiguity results. The book contains an elementary introduction to the main topics: theory of martingales and stochastic integrales, Skorokhod topology, etc., as well as a large number of results which have never appeared in book form, and some entirely new results. It should be useful to the professional probabilist or mathematical statistician, and of interest also to graduate students.
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