Albert Hofmann, who died in 2008 aged 102, synthesised LSD in 1938. Although his work produced other important drugs, it was LSD that shaped his career. Shortly before his death, Hoffman approved a new and updated translation of his autobiography (first published by McGraw Hill in 1979). It appears here for the first time in print.
The acclaimed discoverer of LSD’s personal experiences and thoughts on chemistry, the natural sciences, mind-altering drugs, the soul, and the search for happiness • Shares a different side of the father of LSD, one known only to his friends and close colleagues • Explains Hofmann’s different methods of pharmaceutical research based on traditional plant medicine • Includes the poetry of this mystical prophet of psychedelic science Best known as the first person to synthesize, ingest, and discover the psychedelic effects of LSD, Albert Hofmann was more than just a chemist. A pioneer in the field of visionary plant research, he was one of the first people to suggest the use of entheogens for psychological healing and spiritual growth. His insights into the consciousness-expanding effects of psychedelics as well as human nature, the psyche, and the nature of reality earned him a reputation as a mystical scientist and visionary philosopher. This book--Hofmann’s last work before his death in 2008 at the age of 102--offers the acclaimed scientist’s personal experiences and thoughts on chemistry, the natural sciences, mind-altering drugs, the soul, and the search for happiness and meaning in life. Hofmann explains different methods of pharmaceutical research based on traditional plant medicine and discusses psilocybin, the active compound in psychedelic mushrooms that he discovered. He examines the psychological role of psychoactives, their therapeutic potential, and their use in easing the life-to-death transition. Sharing a different side of the father of LSD, one known only to his friends and close colleagues, this book also includes the poetry of this mystical prophet of psychedelic science.
This is the story of LSD told by a concerned yet hopeful father, organic chemist Albert Hofmann, Ph.D. He traces LSD's path from a promising psychiatric research medicine to a recreational drug sparking hysteria and prohibition. In LSD: My Problem Child, we follow Dr. Hofmann's trek across Mexico to discover sacred plants related to LSD, and listen in as he corresponds with other notable figures about his remarkable discovery. Underlying it all is Dr. Hofmann's powerful conclusion that mystical experiences may be our planet's best hope for survival. Whether induced by LSD, meditation, or arising spontaneously, such experiences help us to comprehend "the wonder, the mystery of the divine, in the microcosm of the atom, in the macrocosm of the spiral nebula, in the seeds of plants, in the body and soul of people." More than sixty years after the birth of Albert Hofmann's problem child, his vision of its true potential is more relevant, and more needed, than ever.
The Magnificent Scientists and their Fabulous Accomplishments A Fantastic Dream and Journey into the Past, Present and Future In the World of Chemistry
This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity, along with methods to investigate their role on adverse drug reactions. Unites both the metabolism and transporter components of drug toxicity – two aspects not normally connected and the latter often neglected Familiarizes readers with the mechanism and species differences in drug metabolizing enzymes and transporters Discusses promising approaches to accurately predict human drug toxicity via the incorporation of human drug metabolism in toxicity evaluation
Written by internationally eminent experts in cardiovascular imaging, this volume provides state-of-the-art information on the use of MRI and CT in the assessment of cardiac and vascular diseases. This third edition, now in four-color, reflects recent significant advances in cardiovascular MRI technology and the continuing emergence of multi-detector CT as an important diagnostic modality, particularly for ischemic heart disease. Seven new chapters have been added including chapters on anatomy, cardiovascular MR in infants/children, assessing myocardial viability, risk assessment in ischemic heart disease and MR guidance.
Molecular and Cell Biology of the Liver features the latest research findings regarding liver structure and function. A unique feature of the book is the brief science reviews that are included in each chapter which provide essential background information to allow readers to better grasp the subject matter within a chapter. The book covers liver biology from the molecular level to groups of liver cells and explains how groups of hepatocytes interact in similar microenvironments. Other important cell types found in the liver are also examined. Illustrations ranging from electron micrographs to fully rendered drawings act as visual aids to help readers understand complex structural-functional interactions. Molecular and Cell Biology of the Liver will benefit hepatologists, gastroenterologists, cell biologists, anatomists, toxicologists, and other researchers interested in liver structure and function.
Albert Fuller's close friendship with Alice Tully over a period of more than thirty years allows him unique insight into her eventful life and colorful personality. The daughter of a Corning heiress and a state senator, Miss Tully trained as a singer in Europe before turning her love of music toward enlightened philanthropy. Chair of the board of directors for the Chamber Music Society of Lincoln Center for nearly twenty-five years, she also served on the boards of the Metropolitan Opera, the New York Philharmonic, and The Juilliard School, and as a trustee of the Metropolitan Museum of Art, the Pierpont Morgan Library, and the Museum of Modern Art. For her cultural contributions, New York City awarded her the Handel Medallion, and France conferred on her the three steps of the National Order of Merit as well as the prestigious Legion of Honor."--BOOK JACKET.
Public procurement and competition law are both important fields of EU law and policy, intimately intertwined in the creation of the internal market. Hitherto their close connection has been noted, but not closely examined. This work is the most comprehensive attempt to date to explain the many ways in which these fields, often considered independent of one another, interact and overlap in the creation of the internal market. This process of convergence between competition and public procurement law is particularly apparent in the 2014 Directives on public procurement, which consolidate the principle of competition in terms very close to those advanced by the author in the first edition. This second edition builds upon this approach and continues to ask how competition law principles inform and condition public procurement rules, and whether the latter (in their revised form) are adequate to ensure that competition is not distorted. The second edition also deepens the analysis of the market behaviour of the public buyer from a competition perspective. Proceeding through a careful assessment of the general rules of competition and public procurement, the book constantly tests the efficacy of these rules against a standard of the proper functioning of undistorted competition in the market for public procurement. It also traces the increasing relevance of competition considerations in the case law of the Court of Justice of the European Union and sets out criteria and recommendations to continue influencing the development of EU Economic Law.
In this highly interesting book, three pioneering investigators provide an account of the discovery and investigation of the nuclear and chemical properties of the twenty presently known transuranium elements. The neutron irradiation of uranium led to the discovery of nuclear fission in 1938 and then to the first transuranium element, neptunium (atomic number 93), in 1940. Plutonium (94) quickly followed and the next nine elements completed the actinide series by 1961. Investigation of the chemical properties of the actinides was followed more recently by chemical studies of the first three transactinides — rutherfordium (104), hahnium (105), and seaborgium (106). Recent discoveries have extended the known elements to 112./a
This groundbreaking work, which established the reputation of Albert Schweitzer as a theologian, traces the search for the historical figure of Jesus (apart from the Christ of faith) and establishes the author's own views.
While there is no easy way to define terrorism, it may generally be viewed as a method of violence in which civilians are targeted with the objective of forcing a perceived enemy into submission by creating fear, demoralization, and political friction in the population under attack. At one time a marginal field of study in the social sciences, terrorism is now very much in center stage. The 1970s terrorist attacks by the PLO, the Provisional Irish Republican Army, the Popular Front for the Liberation of Palestine, the Japanese Red Army, the Unabomber, Aum Shinrikyo, Timothy McVeigh, the World Trade Center attacks, the assault on a school in Russia, and suicide bombers have all made the term "terrorism" an all-too-common part of our vocabulary. This edition of Political Terrorism was originally published in the 1980s, well before some of the horrific events noted above. This monumental collection of definitions, conceptual frameworks, paradigmatic formulations, and bibliographic sources is being reissued in paperback now as a resource for the expanding community of researchers on the subject of terrorism. This is a carefully constructed guide to one of the most urgent issues of the world today. When the first edition was originally published, Choice noted, "This extremely useful reference tool should be part of any serious social science collection." Chronicles of Culture called it "a tremendously comprehensive book about a subject that any who have anything to lose--from property to liberty, life to limbs--should be forewarned against." Alex P. Schmid received his Ph.D. from the University of Zrich, Switzerland, and is a professor in the Department of Political Science at Leiden University. He is the coauthor, with Albert J. Jongman, of Soviet Military Interventions since 1945, available from Transaction. Albert J. Jongman is principal researcher for PIOOM, the Interdisciplinary Research Programme on Causes of Human Rights Violations, and has been a research assistant at the SIPRI in Sweden. He is the author of Monitoring Human Rights Violations (State Violence, State Terrorism, and Human Rights).Irving Louis Horowitz is Hannah Arendt Distinguished University Professor Emeritus of Sociology and Political Science at Rutgers University, and the chairman and editorial director of Transaction Publishers.
The acclaimed discoverer of LSD’s personal experiences and thoughts on chemistry, the natural sciences, mind-altering drugs, the soul, and the search for happiness • Shares a different side of the father of LSD, one known only to his friends and close colleagues • Explains Hofmann’s different methods of pharmaceutical research based on traditional plant medicine • Includes the poetry of this mystical prophet of psychedelic science Best known as the first person to synthesize, ingest, and discover the psychedelic effects of LSD, Albert Hofmann was more than just a chemist. A pioneer in the field of visionary plant research, he was one of the first people to suggest the use of entheogens for psychological healing and spiritual growth. His insights into the consciousness-expanding effects of psychedelics as well as human nature, the psyche, and the nature of reality earned him a reputation as a mystical scientist and visionary philosopher. This book--Hofmann’s last work before his death in 2008 at the age of 102--offers the acclaimed scientist’s personal experiences and thoughts on chemistry, the natural sciences, mind-altering drugs, the soul, and the search for happiness and meaning in life. Hofmann explains different methods of pharmaceutical research based on traditional plant medicine and discusses psilocybin, the active compound in psychedelic mushrooms that he discovered. He examines the psychological role of psychoactives, their therapeutic potential, and their use in easing the life-to-death transition. Sharing a different side of the father of LSD, one known only to his friends and close colleagues, this book also includes the poetry of this mystical prophet of psychedelic science.
Faster, cheaper and environmentally friendly, these are the criteria for designing new reactions and this is the challenge faced by many chemical engineers today. Based on courses thaught by the authors, this advanced textbook discusses opportunities for carrying out reactions on an industrial level in a technically controllable, sustainable, costeffective and safe manner. Adopting a practical approach, it describes how miniaturized devices (mixers, reactors, heat exchangers, and separators) are used successfully for process intensification, focusing on the engineering aspects of microstrctured devices, such as their design and main chracteristics for homogeneous and multiphase reactions. It adresses the conditions under which microstructured devices are beneficial, how they should be designed, and how such devices can be integrated in an existing chemical process. Case studies show how the knowledge gained can be applied for particular processes. The textbook is essential for master and doctoral students, as well as for professional chemists and chemical engineers working in this area.
Television programme format transfer is the process whereby the basic idea or ingredient of a programme is used to produce a new version of the programme. With Polyglot TV, Albert Moran offers a detailed explanation of the process.
This book highlights the current and recent state-of-the-art developments in energy harvesting systems for health supervising applications. It explores the exciting potential of energy harvesting as a crosscutting field of research to intersect with other areas to envisage new products, solutions, and applications. Among all these new opportunities for synergy, there is a research area that fully matches the features offered by energy harvesting with its power supply's main needs- health supervising (HS), which consists of monitoring the health or operating conditions of anything, such as structures, buildings, public health, environment, etc. The book covers the hand in hand evolution towards a new paradigm: truly self-powered devices based on a single transducer acting as a sensor and as power source simultaneously and efficiently. This evolution is illustrated by the concept and implementation of novel state-of-the-art architecture for self-powered energy harvesting systems for applications that range from structural health monitoring to point-of-care medical devices.
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