Over the past two decades a number of attempts have been made, with varying degrees of success, to collect in a single treatise available information on the basic and applied pharmacology and biochemical mechanism of action of antineoplastic and immunosuppressive agents. The logarithmic growth of knowledge in this field has made it progressively more difficult to do justice to all aspects of this topic, and it is possible that the present handbook, more than four years in preparation, may be the last attempt to survey in a. single volume the entire field of drugs em ployed in cancer chemotherapy and immunosuppression. Even in the present instance, it has proved necessary for practical reasons to publish the material in two parts, although the plan of the work constitutes, at least in the editors' view, a single integrated treatment of this research area. A number of factors have contributed to the continuous expansion of research in the areas of cancer chemotherapy and immunosuppression. Active compounds have been emerging at ever-increasing rates from experimental tumor screening systems maintained by a variety of private and governmental laboratories through out the world. At the molecular level, knowledge of the modes of action of estab lished agents has continued to expand, and has permitted rational drug design to playa significantly greater role in a process which, in its early years, depended almost completely upon empirical and fortuitous observations.
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
All aspects of the relationship between the elaboration of exoenzymes and the virulence of bacteria are addressed in the following pages. The authors have provided the most current information available in their areas of expertise. In circumstances where definitive information is lacking, the speculations of the authors should prove interesting to the reader.
Science affects us all-in the words of Albert Einstein, "The whole of science is nothing more than a refinement of everyday thinking." It is therefore fascinating to discover the thoughts of scientists, philosophers, humanists, poets, theologians, politicians, and other miscellaneous mortals on this most important of subjects. A Dictionary of Scientific Quotations is a personal selection of scientific quotations by Professor Alan L Mackay that includes graffiti, lines of song, proverbs, and poetry. Whether you believe that "All problems are finally scientific problems" (George Bernard Shaw) or that "Imagination is more important than knowledge" (Einstein), it is without doubt that "It is a good thing for an uneducated man to read books of quotations" (Churchill). You will be charmed and delighted by this collection and remember, "'Why,'" said the Dodo, "'the best way to explain it is to do it'" (Alice in Wonderland, Lewis Carroll).
Cataract Surgery from Routine to Complex: A Practical Guide provides eye care professionals guidance on what to do and how to avoid potential complications in all aspects of cataract surgery, just as if the world’s experts were by your side. Drs. Randy Olson, George Jin, Ike Ahmed, Alan Crandall, Robert Cionni, and Jason Jones concisely provide a wealth of information, including a detailed list of key issues and considerations for virtually all the possible contingencies of the procedure. Some Topics and Sections Include: -Examination Pupil size, ocular dominance, biometry, and more -IOL Choice Monofocal: aspheric vs. traditional; presbyopia-correcting: mutifocal vs. accommodating; toric, and more -Routine Cataract Surgery Microincision cataract surgery, OVD selection, current phacoemulsification techniques, and more -Complex Cataract Surgery Hypermature cataract, small pupil, pseudoexfoliation, nanophthalmos, pediatric cataract, and more Intra-Operative Complications Wound burn, posterior capsular rupture, shallow anterior chamber, and more -Patient Assessment Visual acuity, refraction, visual quality, and more -Postoperative Complications Endophthalmitis, toxic anterior segment syndrome, IOL dislocation, and more Cataract Surgery from Routine to Complex also includes a companion website that provides more than 2 hours of learning with 38 edited and narrated video presentations, perfectly complementing the procedures discussed inside the text. Cataract Surgery from Routine to Complex is the combination of a practical guide with broad academic underpinnings along with current controversial subjects on cataract surgery, making it ideal for eye care professionals who wish to update their knowledge and translate it into improved surgical techniques and better cataract patient education.
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