This book explores the theoretical paradoxes and practical dilemmas that flow from the still radical idea that in a democracy it is the people who rule, and argues that accepting the open and uncertain character of democratic politics can lead to more sustainable and widespread forms of democratic engagement. The author engages theorists from a range of democratic thoughtRousseau, Arendt, Benhabib, Sandel, Laclau, and Mouffeto show how each either ignores or downplays the difficulties that democratic principles pose. Though there can be no entirely valid solution to the paradoxes that plague democracy, the author nonetheless argues that democratic politicsparticularly under contemporary conditions of social fragmentation and insecurityurgently requires new practical and rhetorical strategies. The book concludes by addressing the American context, elaborating the need for a language of democratic engagement less ensnared in the anti-political logic of moralism and resentment that now characterizes the American political spectrum.
Historians have long struggled with the questions of historical relativism, objectivity, and standards of proof and evidence. Intellectual historian Alan Spitzer focuses on the contradiction between theory and practice by presenting case studies of four politically charged debates about the past: the response to the report of the commission chaired by John Dewey that evaluated the accusations made against Leon Trotsky in the Moscow Purge Trials of 1937, the Dreyfus Affair in turn-of-the-century France, the allegations about the extent and meaning of literary critic Paul de Man's complicity with the German occupation forces in wartime Belgium, and Ronald Reagan's justification for his 1987 visit to a German cemetery where Nazi SS officers are buried. Spitzer's argument centers on the ways in which the authority of 'objective' criteria for historical judgment are introduced in politicized disputes about the past, regardless of the theoretical qualification or repudiation of such standards. The higher the political stakes, the more likely the antagonists are to appeal to generally warranted standards of relevant evidence and rational inference. Spitzer's commentary speaks to issues that transcend the specific content of the four cases he discusses.
This volume provides a thorough and well-balanced review of the topic of conduct disorders in childhood and adolescence. An opening chapter gives the reader a good sense of the nature, complexity, and magnitude of the problem for parents, caretakers, and mental health professionals; the remainder of the book explains what we currently know about children and adolescents with behavior problems. One chapter each is devoted to diagnosis and assessment, characteristics of the disorder, treatment, prevention, and directions for future research and social policy." --Matthjis Koopmans in Journal of Adolescence "This is another excellent little book, in the Sage Developmental Clinical Psychology and Psychiatry Series. Read and enjoy. --Ewen Rennie in BPS Division of Educational & Child Psychology
The interpretation of anaphora - how we interpret expressions such as definite pronouns (he, she, it) and verbal elliptical phrases (such as "did so, too") in the course of ordinary conversation or reading - is an important aspect of language comprehension. In this book the author examines the research and evidence on anaphor interpretation within the context of the mental models theory of comprehension, arguing that the notion of a mental model is essential to the detailed description of the processes of anaphor resolution. The general philosophy of the mental models approach and the nature of mental models themselves and their role in language processing is discussed, followed by a review of methodological issues that bear on the interpretation of psychological research findings. Against this background, the author's own research on areas such as deep and surface anaphora, reference into anaphoric islands, the role of implicit causality in anaphor resolution and the use of pronouns to refer to characters introduced by stereotyped role names is presented. At all times the author's research is set within the context of the general literature on anaphor resolution derived from the disciplines of linguistics, psycholinguistics, philosophy and computational linguistics, ensuring that the book will be of interest to advanced students and researchers in these fields.
Mexican American Baseball in the Central Coast pays tribute to the teams and players who brought joy and honor to their fans and communities in Ventura and Santa Barbara Counties. Baseball was played before enthusiastic crowds in Piru, Santa Paula, Fillmore, Ventura, Oxnard, Camarillo, Ojai, Carpinteria, Santa Barbara, Goleta, Santa Maria, Guadalupe, Lompoc, and other communities. Players and their families helped create the economic infrastructure and prosperity that are evident today in the Central Coast. For women, softball was a social counterbalance to the strict cultural roles defined by society. Many former players dedicated their lives to the unrelenting struggle for social justice, while others devoted themselves to youth sports. This book remedies the glaring omission of baseball images and stories of Mexican American neighborhoods in the Central Coast of California.
In this unique history of the “Lost Battalion” of World War I, Alan D. Gaff tells for the first time the story of the 77th Division from the perspective of the soldiers in the ranks. On October 2, 1918, Maj. Charles W. Whittlesey led the 77th Division in a successful attack on German defenses in the Argonne Forest of northeastern France. His unit, comprised of men of a wide mix of ethnic backgrounds from New York City and the western states, was not a battalion nor was it ever “lost,” but once a newspaper editor applied the term “lost battalion” to the episode, it stuck. Gaff draws from new, unimpeachable sources—such as sworn testimony by soldiers who survived the ordeal—to correct the myths and legends and to reveal what really happened in the Argonne Forest during early October 1918.
Alan Cross is the preeminent chronicler of popular music. Here he provides a history of the mysterious and eccentric rock band Tool. This look at "a band that stays so deep in the shadows that they could walk past 99 percent of their fans on the street and never be recognized" is adapted from the audiobook.
Confessions of a Government Man is filled with astute, often hilarious memoirs of Alan Greenberg's thirty-nine year career with the U.S. General Services Administration. His real-life tales of deception and sleight-of-hand maneuvers in high government places include a cast of characters worthy of Hollywood. A few of his stories are a bit risque and some show that incisive philosophical advice sometimes comes from the most unlikely sources. Throughout we see plenty of salty New York culture. At various times Greenberg was threatened with arrest and contempt of court, detained at gunpoint by a judge, had an off-the-cuff wisecrack end up on national television, and even had a curse put on him by a spiritual leader. Through it all he maintained his sense of humor. Greenberg gives us a true insider's vantage point. With contracting authority for a stack of taxpayer money, which went into the billions and had the potential for providing a lot of lifetime meal tickets, it was little wonder that Greenberg was very popular with the construction industry and any politician with an eye for publicity. Many of his stories give the reader insight into realities that media coverage somehow missed. Reporters, in their zeal to dig up dirt, often followed minutia while the true stories went unreported. One example was the $10 million "savings" to a project, which was actually a $40 million addition. Amazingly, nobody was the wiser. Experience is the best teacher, and during his many years on the job, Alan Greenberg knew what it was like to be under siege by the media, the Congress, the White House and concerned citizens. He developed rules of survival that enabled him to be a success in the large, complex bureaucracy of our government. He shares these years with us, happily turning them into a delightful and entertaining romp. * * * "Professor Parkinson would be proud. This book should be required reading in every business school. Solid lessons in business and life told in a most unique manner. Read the chapters in any sequence and the result is still the same - sound business logic with unforgettable memory joggers." - Barry Becher, Ginsu Knife Creator + co-author of The Wisdom of Ginsu "Mr. Greenberg's keen insight and humor make this an indispensable guide for anyone trying to survive and flourish in a large organization." - Len Fried, Director of Manufacturing Excellence (Retired), IBM Microelectronics "As our 'big-ass suit' author states...'they woke up on third base and thought they hit a triple.' Mr. Greenberg hit a home run with this most entertaining book. Well done, kid from Brooklyn, and CONGRATULATIONS for allowing us plain folk to see what really goes on behind the scenes in our government with its Damon Runyonesque cast of characters." - Lew Duberman, CFO (Retired), Helene Curtis Industries, Inc.
The Act of Union, coming into effect on 1 January 1801, portended the integration of Ireland into a unified, if not necessarily uniform, community. This volume treats the complexities, perspectives, methodologies and debates on the themes of the years between 1801 and 1879. Its focus is the making of the Union, the Catholic question, the age of Daniel O'Connell, the famine and its consequences, emigration and settlement in new lands, post-famine politics, religious awakenings, Fenianism, the rise of home rule politics and emergent feminism.
Consistently lauded for its comprehensiveness and full-color color presentation, the latest edition of Rheumatology by Marc C. Hochberg, MD, MPH et al. continues the tradition of excellence of previous editions. Designed to meet the needs of the practicing clinician, it provides extensive, authoritative coverage of rheumatic disease from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format covering all major disorders of the musculoskeletal system in complete, self-contained chapters. Get trusted perspectives and insights from chapters co-authored by internationally renowned leaders in the field, 25% of whom are new to this edition. Track disease progression and treat patients more effectively with the most current information, including 22 new chapters on genetic findings, imaging outcomes, and cell and biologic therapies as well as rheumatoid arthritis and SLE. Incorporate the latest findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics.
This book offers a provocative rereading of the early history of Chan Buddhism (Zen). Working from a history-of-religions point of view that asks how and why certain literary tropes were chosen to depict the essence of the Buddhist tradition to Chinese readers, this analysis focuses on the narrative logics of the early Chan genealogies—the seventh-and eighth-century lineage texts that claimed that certain high-profile Chinese men were descendents of Bodhidharma and the Buddha. This book argues that early Chan's image of the perfect-master-who-owns-tradition was constructed for reasons that have little to do with Buddhist practice, new styles of enlightened wisdom, or "orthodoxy," and much more to do with politics, property, geography, and, of course, new forms of writing.
The Funeral Casino is a heretical ethnography of the global age. Setting his book within Thailand's pro-democracy movement and the street massacres that accompanied it, Alan Klima offers a strikingly original interpretation of mass-mediated violence through a study of funeral gambling and Buddhist meditation on death. The fieldwork for the book began in 1992, when a freewheeling market of illegal "massacre-imagery" videos blossomed in Bangkok on the very site where, days earlier, for the third time in two decades, a military-controlled government had killed scores of unarmed pro-democracy protesters. Such killings and their subsequent representation have lent force to Thailand's transition from military control to a "media-financial complex." Probing the ways in which death is marketed, visualized, and remembered through practices both local and global, Klima inverts conventional relationships between ethnography and theory through a compelling narrative that reveals a surprising new direction available to anthropology and critical theory. Ethnography here engages with the philosophy of activism and the politics of memory, media representation of violence, and globalization. In focusing on the particular array of tactics in Thai Buddhism and protest politics for connecting death and life, past and present, this book unveils a vivid and haunting picture of community, responsibility, and accountability in the new world order.
Christian theology of religions remains a central component of the Christian response to global religious diversity. In the face of theological refusals to engage with issues of religious absolutism and new impressions from interreligious encounters, this book seeks to inject fresh energy into a debate that has stalled in recent years. The encounter between Christians and people of different religious persuasions raises questions of how to interpret Christian absolutism for a new and developing consciousness that values the experience of the religious other. This book argues that interreligious dialogue, interreligious ethical collaboration, and comparative studies all point to a pluralist future, where we are obliged to recognize the spiritual authenticity of the experience animating many religions. Building friendly relations between faith communities is to be applauded but it is insufficient in the face of the many challenges confronting the global human community. Whether we are speaking of cooperation in civil society, peace in the world, or the overarching ecological crisis encompassing the planet as a whole, the acceptance of the diversity of religions as a positive religious value will strengthen the sense of global responsibility that is needed.
A superb learning and teaching resource, this structured introduction to fluid mechanics covers everything the engineer needs to know: the nature of fluids, hydrostatics, differential and integral relations, dimensional analysis, viscous flows, and another topics. Solutions to selected problems. 760 illustrations. 1985 edition.
This revised textbook is designed for undergraduate courses in cognitive psychology. It approaches cognitive psychology by asking what it says about how people carry out everyday activities: how people organize and use their knowledge in order to behave appropriately in the world in which they live.; Each chapter of the book starts with an example and then uses this to introduce some aspect of the overall cognitive system. Through such examples of cognition in action, important components of the cognitive system are identified, and their interrelationships highlighted. Thus the text demonstrates that each part of the cognitive system can only be understood properly in its place in the functioning of the whole.; This edition features increased coverage of neuropsychological and connectionist approaches to cognition.
Discusses the 1st Amendment right to free speech, with particular emphasis on defining and limiting dangerous speech, obscene expression, and the freedom of the press.
More than 1 in 7 American children get diagnosed with ADHD - three times what experts have said is appropriate - meaning that millions of kids are misdiagnosed and taking medications such as Adderall or Concerta for a psychiatric condition they probably do not have. The numbers rise every year. And still, many experts and drug companies deny any cause for concern. In fact, they say that adults and the rest of the world should embrace ADHD and that its medications will transform their lives. -- Provided by publisher.
Can today’s society, increasingly captivated by a constant flow of information, share a sense of history? How did our media-making forebears balance the tension between the present and the absent, the individual and the collective, the static and the dynamic—and how do our current digital networks disrupt these same balances? Can our social media, with its fleeting nature, even be considered social at all? In Friending the Past, Alan Liu proposes fresh answers to these innovative questions of connection. He explores how we can learn from the relationship between past societies whose media forms fostered a communal and self-aware sense of history—such as prehistorical oral societies with robust storytelling cultures, or the great print works of nineteenth-century historicism—and our own instantaneous present. He concludes with a surprising look at how the sense of history exemplified in today’s JavaScript timelines compares to the temporality found in Romantic poetry. Interlaced among these inquiries, Liu shows how extensive “network archaeologies” can be constructed as novel ways of thinking about our affiliations with time and with each other. These conceptual architectures of period and age are also always media structures, scaffolded with the outlines of what we mean by history. Thinking about our own time, Liu wonders if the digital, networked future can sustain a similar sense of history.
This comprehensive, but practical, reference is an informative guide to the management of acute respiratory problems in the hospital setting. Evaluation of the patient with breathing difficulties is often challenging, since the differential diagnosis is broad and the use of the wrong treatment can exacerbate the problem. This book helps the practis
In No Limits, Michael Phelps - perhaps the greatest Olympic competitor the world has ever seen - will show us the secrets to his remarkable success, from training to execution. Behind his tally of Olympic gold medals - more than any athlete throughout history - lies a consistent approach to competition, a determination to win, mental preparation, and a straightforward passion for his sport. One of his mottos is 'Performance is Reality', and it typifies his attitude about swimming. No Limits goes behind the scenes to explore the hard work, sacrifice, and dedication that catapulted Phelps into the international spotlight. Phelps will share remarkable anecdotes about family, his coach, his passion for the sport, and the wisdom that he has gained from unexpected challenges and obstacles. Highlighting memorable races and valuable lessons from throughout his career, Phelps offers candid insight into the mind and experiences of a world champion. No Limits will inspire anyone to follow their passion straight to the finish line.
(Spring 2010) This historical novel finds President Reagan at odds with his daughter, Vice President, White House Staff and Cabinet as Ronnie and Nancy try to do the best acting of their lives to leave the White House, alive. (unabridged edition) Our most loved and hated President after Kennedy and before Obama, Ronnie struggles to defeat the ‘Evil Empire’ and not lose his mind to Alzheimer’s dementia. Can he still trust Bill Casey and George Bush, George Shultz, Selwa Roosevelt and Mike Deaver? Can Ronnie find out who's pulling his strings? A fervent anti-Communist and Nazi hater praised by his wife Nancy and ultra-conservatives, groomed by Bechtel Corporation since 1950 and sold StarWars by Dick Cheney and Paul Nitze during the most scandal-ridden presidency in American history, daughter Patti, college students and flower children despised Reagan for supporting the Vietnam War and Contra death squads and felt the Reagan-Bush Administration was run by Nazis. As it turns out, it was. This historical novel documents the foreign policy, national security and monetary policies of the Reagan-Bush Administration were run by Nazis thru the life of character Reinhard Gehlen, Hitler’s chief of Foreign Armies East intelligence, whom Dulles hired to run and train CIA as Freikorps Nazi deathsquad torturers, terrorists and assassins who then trained the Contras ...that Gehlen was later handled by Bill Casey (Ronnie's campaign manager) then George Bush (Ronnie's vice president) to fight, exaggerate and invent the Cold War in order to capture the Russian Baku oil fields. Based on autobiographies of the Reagan family, Cabinet, and White House Staff, the 650-page book includes a 250-page epilog of documentation and a 50-pg researchers' index, footnotes, and an extensive appendix including charts from: Staff Report, Committee on Banking, Currency & Housing, House of Representatives, 94th Congress, 2d session, Aug. 1976 -- Federal Reserve Directors, a Study of Corporate & Banking Influence. The charts trace from 1913 to present the family dynasties of the private owners and interlocking directorate of the Federal Reserve Bank and other G-8 central banks (the World Order and New World Order) whom Bill Casey, George Shultz, the Bushes, bin Ladens, Thyssens, Rockefellers, Rothschilds, Browns, Harrimans and Reinhard Gehlen worked for and against whose family ancestors the American Revolution was fought and whose family decendents today continue to dominate the financial, political, economic, and bailout and foreclosure landscape with financial terrorism. Additionally, the historical novel follows the family dynasties of the private owners of the interlocking directorate of the Fed/G8 including Bank of England and Bundesbank and other central banks involved in the American Revolution of 1776, the American Civil War, the depressions in the late 1800s and early 1900s, the founding of the privately owned Federal Reserve Bank in 1913, WWI, the financing of the Bolshevik party from New York and thru Ruskombank which supplied U.S. technology and weapons and military vehicles to communist Russia who supplied them to the Viet Cong to kill Americans. Appendices also document the previously hypothesized money-issuing class that prints and owns our money that rules the upper class, middle class, working class, and unemployed classes. The appendix also includes documentation of the Clinton-era involvement with HUD corruption when Bill was Governor and Hillary was a HUD attorney. HUD sold billions of dollars of foreclosed properties in East L.A. at ten cents on the dollar to the Fed-founded Dillion-Read bank. Ronnie was advised about the marriage of the oil and illegal drug industries, and the case by the European Union and Central and South American countries against Reynolds Tobacco for laundering heroin and cocaine profits with Camel Cigarettes.
Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. - Comprehensively explains the use of population genetics and genomics in medical applications and research - Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals - Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now
The potato famines of the nineteenth century were long attributed to Irish indolence. The Stalinist system was blamed on a Russian proclivity for autocracy. Muslim men have been accused of an inclination to terrorism. Is political behavior really the result of cultural upbringing, or does the vast range of human political action stem more from institutional and structural constraints? This important new book carefully examines the role of institutions and civic culture in the establishment of political norms. Jackman and Miller methodically refute the Weberian cultural theory of politics and build in its place a persuasive case for the ways in which institutions shape the political behavior of ordinary citizens. Their rigorous examination of grassroots electoral participation reveals no evidence for even a residual effect of cultural values on political behavior, but instead provides consistent support for the institutional view. Before Norms speaks to urgent debates among political scientists and sociologists over the origins of individual political behavior. Robert W. Jackman is Professor of Political Science at the University of California, Davis. Ross A. Miller is Associate Professor of Political Science at Santa Clara University.
In its 9th edition, AHRI-endorsed Human Resource Management continues to provide a strong conceptual and practical framework for students of human resource management. The successful integrative strategic HRM model is retained and the most recent developments in human resource management theories and practices are explored. A multitude of contemporary regional and international examples are integrated throughout, alongside an expanded coverage on ethics and a focus on critical analysis. Thoroughly revised and updated with the latest research findings, this edition incorporates a wealth of new material including: corporate social responsibility, ethics, sustainable management practice, leadership, talent management, industrial relations, and retains its focus on core human resource elements. Accompanied by online study tools which help to reinforce concepts, apply critical thinking and enhance skills, this 9th edition of Human Resource Management offers the complete learning experience required to succeed in human resource management.
Philadelphia has been a hockey town since 1897. Before and even during the Philadelphia Flyers' tenure, other teams--the Ramblers, the Quakers and the Firebirds, among others--called the city home, for better or for worse. The first of its kind, this comprehensive history covers the teams and players that graced the ice from the turn of the 20th century through the 2009 demise of the Philadelphia Phantoms. Offering something for every Philly hockey fan, the author tells the stories of the 10 pro teams that played the world's fastest game in the City of Brotherly Love.
The Historical Dictionary of British Spy Fiction is a detailed overview of the rich history and achievements of the British espionage story in literature, cinema and television. It provides detailed yet accessible information on numerous individual authors, novels, films, filmmakers, television dramas and significant themes within the broader field of the British spy story. It contains a wealth of facts, insights and perspectives, and represents the best single source for the study and appreciation of British spy fiction. British spy fiction is widely regarded as the most significant and accomplished in the world and this book is the first attempt to bring together an informed survey of the achievements in the British spy story in literature, cinema and television. The Historical Dictionary of British Spy Fiction contains a chronology, an introduction, appendixes, and an extensive bibliography. The dictionary section has over 200 cross-referenced entries on individual authors, stories, films, filmmakers, television shows and the various sub-genres of the British spy story. This book is an excellent access point for students, researchers, and anyone wanting to know more about British spy fiction.
This Encyclopedia provides description and analysis of the terms, concepts and issues of social and cultural anthropology. International in authorship and coverage, this accessible work is fully indexed and cross-referenced.
Osman, the founder of the Ottoman Empire, had a dream in which a tree sprouted from his navel. As the tree grew, its shade covered the earth; as Osman’s empire grew, it, too, covered the earth. This is the most widely accepted foundation myth of the longest-lasting empire in the history of Islam, and offers a telling clue to its unique legacy. Underlying every aspect of the Ottoman Empire’s epic history—from its founding around 1300 to its end in the twentieth century—is its successful management of natural resources. Under Osman’s Tree analyzes this rich environmental history to understand the most remarkable qualities of the Ottoman Empire—its longevity, politics, economy, and society. The early modern Middle East was the world’s most crucial zone of connection and interaction. Accordingly, the Ottoman Empire’s many varied environments affected and were affected by global trade, climate, and disease. From down in the mud of Egypt’s canals to up in the treetops of Anatolia, Alan Mikhail tackles major aspects of the Middle East’s environmental history: natural resource management, climate, human and animal labor, energy, water control, disease, and politics. He also points to some of the ways in which the region’s dominant religious tradition, Islam, has understood and related to the natural world. Marrying environmental and Ottoman history, Under Osman’s Tree offers a bold new interpretation of the past five hundred years of Middle Eastern history.
The comprehensive guide to the place that brought sport climbing to North America— a full-color, thoroughly updated new edition Smith Rock State Park. It was on the impressive crags of this Oregon hideaway that American sport climbing came into its own, and to this day, some of the hardest climbs in the United States are found on these walls. Alan Watts, who has played a leading role in the development of this popular rock-climbing destination, details more than 1,700 routes at Smith Rock and the surrounding area. This new edition updates hundreds of routes, includes hundreds of new ones, and has new photos of each crag, wall, and route. No other guide is as comprehensive or thorough, and no author more respected for his intimate knowledge of one of the world’s most popular climbing destinations.
Rufinus' vivid account of the battle between the Eastern Emperor Theodosius and the Western usurper Eugenius by the River Frigidus in 394 represents it as the final confrontation between paganism and Christianity. It is indeed widely believed that a largely pagan aristocracy remained a powerful and active force well into the fifth century, sponsoring pagan literary circles, patronage of the classics, and propaganda for the old cults in art and literature. The main focus of much modern scholarship on the end of paganism in the West has been on its supposed stubborn resistance to Christianity. The dismantling of this romantic myth is one of the main goals of Alan Cameron's book. Actually, the book argues, Western paganism petered out much earlier and more rapidly than hitherto assumed. The subject of this book is not the conversion of the last pagans but rather the duration, nature, and consequences of their survival. By re-examining the abundant textual evidence, both Christian (Ambrose, Augustine, Jerome, Paulinus, Prudentius) and "pagan" (Claudian, Macrobius, and Ammianus Marcellinus), as well as the visual evidence (ivory diptychs, illuminated manuscripts, silverware), Cameron shows that most of the activities and artifacts previously identified as hallmarks of a pagan revival were in fact just as important to the life of cultivated Christians. Far from being a subversive activity designed to rally pagans, the acceptance of classical literature, learning, and art by most elite Christians may actually have helped the last reluctant pagans to finally abandon the old cults and adopt Christianity. The culmination of decades of research, The Last Pagans of Rome overturns many long-held assumptions about pagan and Christian culture in the late antique West.
Explores both the benefits and limitations of new UHPLC technology High performance liquid chromatography (HPLC) has been widely used in analytical chemistry and biochemistry to separate, identify, and quantify compounds for decades. The science of liquid chromatography, however, was revolutionized a few years ago with the advent of ultra-high performance liquid chromatography (UHPLC), which made it possible for researchers to analyze sample compounds with greater speed, resolution, and sensitivity. Ultra-High Performance Liquid Chromatography and Its Applications enables readers to maximize the performance of UHPLC as well as develop UHPLC methods tailored to their particular research needs. Readers familiar with HPLC methods will learn how to transfer these methods to a UHPLC platform and vice versa. In addition, the book explores a variety of UHPLC applications designed to support research in such fields as pharmaceuticals, food safety, clinical medicine, and environmental science. The book begins with discussions of UHPLC method development and method transfer between HPLC and UHPLC platforms. It then examines practical aspects of UHPLC. Next, the book covers: Coupling UHPLC with mass spectrometry Potential of shell particles in fast liquid chromatography Determination of abused drugs in human biological matrices Analyses of isoflavones and flavonoids Therapeutic protein characterization Analysis of illicit drugs The final chapter of the book explores the use of UHPLC in drug metabolism and pharmacokinetics studies for traditional Chinese medicine. With its frank discussions of UHPLC's benefits and limitations, Ultra-High Performance Liquid Chromatography and Its Applications equips analytical scientists with the skills and knowledge needed to take full advantage of this new separation technology.
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