Tumors cells no longer confined to an affected organ can be released through lymph and the blood stream, disseminate and form metastases. Metastases to the spine are frequent, may be painful and may occur in an isolated or multiple level manner, they may lead to structural failure of the spinal column and cause com pression of nerve structures resulting in progressive paralysis or in painful radi culopathies. The dinical evaluation as weIl as to tumor pathophysiology are weIl explai ned in two general chapters and then each specific primary tumor is analyzed in a specific chapter. The choice was made to offer a multidisciplinary approach. One may thus find similar aspects repeated in different chapters, yet this is ne ces sary since each part of this textbook can be used as a specific reference. I was impressed by the carefully detailed humane approach to the patient information with care for the patient's dignity. Truthful information is explained dearly enough to give all the elements the patient needs to understand and accept neces sary treatments with a responsible attitude. Previously, when confronted with a patient suffering from a debilitating spine metastasis of a malignant tumor it has been almost always too late to offer anything more than compassionate ineffica cy. Surgical treatment was balanced with life expectancy and then only rarely indicated in certain specific cases.
A beautiful volume that brings to light the forgotten Le Nain brothers, a trio of 17th-century French master painters who specialized in portraiture, religious subjects, and scenes of everyday peasant life In France in the 17th century, the brothers Antoine (c. 1598-1648), Louis (c. 1600/1605-1648), and Mathieu (1607-1677) Le Nain painted images of everyday life for which they became posthumously famous. They are celebrated for their depictions of middle-class leisure activities, and particularly for their representations of peasant families, who gaze out at the viewer. The uncompromising naturalism of these compositions, along with their oddly suspended action, imparts a sense of dignity to their subjects. Featuring more than sixty paintings highlighting the artists' full range of production, including altarpieces, private devotional paintings, portraits, and the poignant images of peasants for which the brothers are best known, this generously illustrated volume presents new research concerning the authorship, dating, and meaning of the works by well-known scholars in the field. Also groundbreaking are the results of a technical study of the paintings, which constitutes a major contribution to the scholarship on the Le Nain brothers.
Organ transplantation has been successfully performed over the last 35 years and the number of organ allograft recipients is steadily increasing. Long-term immunosuppression, necessary for good graft function, inevitably induces undesired effects (particularly infectious and neoplastic ones) among which cutaneous ones are very frequent and potentially life-threatening. This book deals with all aspects of cutaneous disorders that may be encountered in the setting of organ transplantation. It reflects the pioneering work performed since long by Dermatologists in Lyon, in collaboration with teams specialised in kidney, heart, lung, liver and pancreas transplantation.
Tumors cells no longer confined to an affected organ can be released through lymph and the blood stream, disseminate and form metastases. Metastases to the spine are frequent, may be painful and may occur in an isolated or multiple level manner, they may lead to structural failure of the spinal column and cause com pression of nerve structures resulting in progressive paralysis or in painful radi culopathies. The dinical evaluation as weIl as to tumor pathophysiology are weIl explai ned in two general chapters and then each specific primary tumor is analyzed in a specific chapter. The choice was made to offer a multidisciplinary approach. One may thus find similar aspects repeated in different chapters, yet this is ne ces sary since each part of this textbook can be used as a specific reference. I was impressed by the carefully detailed humane approach to the patient information with care for the patient's dignity. Truthful information is explained dearly enough to give all the elements the patient needs to understand and accept neces sary treatments with a responsible attitude. Previously, when confronted with a patient suffering from a debilitating spine metastasis of a malignant tumor it has been almost always too late to offer anything more than compassionate ineffica cy. Surgical treatment was balanced with life expectancy and then only rarely indicated in certain specific cases.
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