Recent advances have carried hepatology to new frontiers. The increasing frequency with which steatotic and cirrhotic livers undergo surgery obliges liver surgeons and hepatologists to understand the molecular mechanisms at play in these situations. Comprehension of the signaling pathways participating in liver regeneration, hepatocellular apoptosis and ischemia/reperfusion injury is essential. This book serves as a source of information to facilitate the reading of the literature and the planning of trials. Translational medicine implies knowledge of the molecular targets of novel therapeutic strategies. It is our goal to stimulate more research that can lead to more exchanges between the laboratory, the clinical ward and the operating room.
This volume contains the third part of the lecture notes of the Asian-French Summer School on Algebraic Geometry and Number Theory, which was held at the Institut des Hautes Etudes Scientifiques (Bures-sur-Yvette) and the Universite Paris-Sud XI (Orsay) in July 2006. This summer school was devoted to the theory of motives and its recent developments and to related topics, notably Shimura varieties and automorphic representations.
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