During sleep, the mammalian brain generates an orderly progression of low frequency oscillations as the brain moves from sleep onset into deep sleep. This book explores the underlying neural mechanisms involved in generating these oscillations through interacting neural assemblies in the thalamus and the cortex. Sleep spindles are involved in the consolidation of experiences in long-term memory during sleep. Written by two leading experts in the field, this book integrates the properties of ion channels, synaptic interactions, and intrinsic cellular mechanisms into biophysical models of neural oscillations in local circuits and distributed networks. In particular, the book focuses on sleep spindles and how they are highjacked by epileptic seizures Reissued in paperback after being unavailable for many years, this revised edition of Thalamocortical Assemblies includes updates to each chapter, highlighting developments since its first publication. The book will be valuable to neuroscientists, neurobiologists, physiologists and computational researchers interested in sleep and memory processes.
In this slim, passionately argued volume - first published to great acclaim in France and considerably updated during the translation process - a deeply involved witness of the massacres takes an unflinching look at recent events in Rwanda and what they can tell us about the nature of genocide. Drawing on his experiences in the killing fields, Destexhe illustrates how genocide is trivialized by superficial contemporary definitions and by modern media and its compulsion to describe any mass killing as genocide. Genocide, Destexhe argues, is the most evil of all crimes as it is directed at the very heart of what it is to be human. Reviewing the three most destructive genocidal campaigns of the twientieth century - the Turkish mass murder of Armenians; the Nazi Holocaust; and the Rwandan cataclysm - the book discusses such central issues as culpability and collective responsibility, the limits of humanitarian intervention, and the complexities of punishing genocidal agents after the fact.
With the end of Moore's law and the emergence of new application needs such as those of the Internet of Things (IoT) or artificial intelligence (AI), neuro-inspired, or neuromorphic, information processing is attracting more and more attention from the scientific community. Its principle is to emulate in a simplified way the formidable machine to process information which is the brain, with neurons and artificial synapses organized in network. These networks can be software and therefore implemented in the form of a computer program but also hardware and produced by nanoelectronic circuits. The material path allows very low energy consumption, and the possibility of faithfully reproducing the shape and dynamics of the action potentials of living neurons (biomimetic approach) or even being up to a thousand times faster (high frequency approach). This path is promising and welcomed by the major manufacturers of nanoelectronics, as circuits can now today integrate several million neurons and artificial synapses.
An unsettling reflection on the twentieth century in its twilight hours in which we are asked to rethink our assumptions about universalism and humanism. While many people look to humanist ideals as a deterrent to nationalist chauvinism, Finkielkraut challenges the abstract idea of universalism by describing the terrible crimes "civilized" Europe has committed in its name.
Neuronal Noise combines experimental, theoretical and computational results to show how noise is inherent to neuronal activity, and how noise can be important for neuronal computations. The book covers many aspects of noise in neurons, with an emphasis on the largest source of noise: synaptic noise. It provides students and young researchers with an overview of the important methods and concepts that have emerged from research in this area. It also provides the specialist with a summary of the large body of sometimes contrasting experimental data, and different theories proposed to explore the computational power that various forms of "noise" can confer to neurons.
In this slim, passionately argued volume - first published to great acclaim in France and considerably updated during the translation process - a deeply involved witness of the massacres takes an unflinching look at recent events in Rwanda and what they can tell us about the nature of genocide. Drawing on his experiences in the killing fields, Destexhe illustrates how genocide is trivialized by superficial contemporary definitions and by modern media and its compulsion to describe any mass killing as genocide. Genocide, Destexhe argues, is the most evil of all crimes as it is directed at the very heart of what it is to be human. Reviewing the three most destructive genocidal campaigns of the twientieth century - the Turkish mass murder of Armenians; the Nazi Holocaust; and the Rwandan cataclysm - the book discusses such central issues as culpability and collective responsibility, the limits of humanitarian intervention, and the complexities of punishing genocidal agents after the fact.
During sleep, the mammalian brain generates an orderly progression of low frequency oscillations as the brain moves from sleep onset into deep sleep. This book explores the underlying neural mechanisms involved in generating these oscillations through interacting neural assemblies in the thalamus and the cortex. Sleep spindles are involved in the consolidation of experiences in long-term memory during sleep. Written by two leading experts in the field, this book integrates the properties of ion channels, synaptic interactions, and intrinsic cellular mechanisms into biophysical models of neural oscillations in local circuits and distributed networks. In particular, the book focuses on sleep spindles and how they are highjacked by epileptic seizures Reissued in paperback after being unavailable for many years, this revised edition of Thalamocortical Assemblies includes updates to each chapter, highlighting developments since its first publication. The book will be valuable to neuroscientists, neurobiologists, physiologists and computational researchers interested in sleep and memory processes.
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