Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement. Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
This book begins with an introduction of pragmatic cluster randomized trials (PCTs) and reviews various pragmatic issues that need to be addressed by statisticians at the design stage. It discusses the advantages and disadvantages of each type of PCT, and provides sample size formulas, sensitivity analyses, and examples for sample size calculation. The generalized estimating equation (GEE) method will be employed to derive sample size formulas for various types of outcomes from the exponential family, including continuous, binary, and count variables. Experimental designs that have been frequently employed in PCTs will be discussed, including cluster randomized designs, matched-pair cluster randomized design, stratified cluster randomized design, stepped-wedge cluster randomized design, longitudinal cluster randomized design, and crossover cluster randomized design. It demonstrates that the GEE approach is flexible to accommodate pragmatic issues such as hierarchical correlation structures, different missing data patterns, randomly varying cluster sizes, etc. It has been reported that the GEE approach leads to under-estimated variance with limited numbers of clusters. The remedy for this limitation is investigated for the design of PCTs. This book can assist practitioners in the design of PCTs by providing a description of the advantages and disadvantages of various PCTs and sample size formulas that address various pragmatic issues, facilitating the proper implementation of PCTs to improve health care. It can also serve as a textbook for biostatistics students at the graduate level to enhance their knowledge or skill in clinical trial design. Key Features: Discuss the advantages and disadvantages of each type of PCTs, and provide sample size formulas, sensitivity analyses, and examples. Address an unmet need for guidance books on sample size calculations for PCTs; A wide variety of experimental designs adopted by PCTs are covered; The sample size solutions can be readily implemented due to the accommodation of common pragmatic issues encountered in real-world practice; Useful to both academic and industrial biostatisticians involved in clinical trial design; Can be used as a textbook for graduate students majoring in statistics and biostatistics.
Since the turn of the millennium South Korea has continued to grapple with transgressions that shook the nation to its core. Following the serial killings of Korea’s raincoat killer, the events that led to the dissolution of the United Progressive Party, the criminal negligence of the owner and also the crew members of the sunken Sewol Ferry, as well as the political scandals of 2016, there has been much public debate about morality, transparency, and the law in South Korea. Yet, despite its prevalence in public discourse, transgression in Korea has not received proper scholarly attention. Transgression in Korea challenges the popular conceptions of transgression as resistance to authority, the collapse of morality, and an attempt at self- empowerment. Examples of transgression from premodern, modern, and contemporary Korea are examined side by side to underscore the possibility of reading transgression in more ways than one. These examples are taken from a devotional screen from medieval Korea, trickster tales from the late Chosŏn period, reports about flesheating humans, newspaper articles about same- sex relationships from colonial Korea, and films about extramarital affairs, wayward youths, and a vengeful vigilante. Bringing together specialists from various disciplines such as history, art history, anthropology, premodern literature, religion, and fi lm studies, the context- sensitive readings of transgression provided in this book suggest that transgression and authority can be seen as forming something other than an antagonistic relationship.
Hannah sympathizes with the pain and sadness of the 1.5th generation of immigrants, and she works for the Navy Seal.Han and his daughter Jennifer are completely inverted as they try to help with the heart of Jesus. With the development of information and transportation, the global village is already one. Life Line Network is a global stage with diverse cultures, races, religions and beliefs, philosophies, and below. However, against this backdrop, it will be a world of justice and justice only when it follows the basic values, namely the conscience and standards that one must follow as a human being. Behind the scenes of the Internet cyber age, which values speed only, are people like Geum-soo, who is abandoning human ethics. Of course, I reflect on and repent on Hannah's arrogance and the start of ignorance. However, Hannah wanted to help the heartbreaking immigrant sorrow. I hope there is no case in the IT era that causes great damage to people who live a true and true life. "Forgive me, Lord, help me." I reflect on my ignorance, arrogance and arrogance. Everyone has no choice but to. deeply repent for the appearance of arrogant life I sincerely wish for a world of justice and justice within the communication and sympathy of the global community. ―
This study critically examines the current state of Synoptic Gospel studies, particularly many scholars' reliance on the Literary Dependence Hypothesis, and endeavors to advance a more balanced approach. The author attempts to deduce the Synoptic Gospels' construction process by meticulously examining the Eucharist and its co-text within these Gospels, by employing a model of Mode Register Analysis based on Systemic Functional Linguistics. This study uncovers the probability that each designated text in the Synoptic Gospels was constructed based on oral Gospel tradition(s) under the influence of each constructor’s identity.
This book explores East Asia’s and the Asia Pacific’s energy security exploring key issues including major trans-border energy projects, major country’s energy mix policy, trans- border pipelines, LNG transfer between nations, balance of power relations between major powers, the North Korean energy situation, energy alliances, Belt and Road Initiative, Indo-Pacific Strategy, World Choke point and more. In particular, this book provides the detailed analysis of the current problems of energy security and diplomacy among various countries as well as policy implications. It will clearly serve as a manual to enhance energy security in the region and boost energy transaction as well as the pioneering step to conceptualize the notion of energy security among political circles, in the diplomatic community and energy industry as well as international relations academics.
The Legal and Economic Analysis of the WTO/FTA System presents a collation of interdisciplinary studies covering a wide range of issues from WTO dispute settlement issues to trade remedy systems and FTA negotiations. The author applies legal as well as economic rationales and methods to analyze core issues in the world trading system and in doing so, sheds an interesting light on various trade issues. The interdisciplinary analysis on WTO and FTA issues provides a unique opportunity to reconsider many conventional trade topics. For instance, the author shows that third country dumping rarely used in the GATT/WTO system may have a new role with economic incentives in the context of FTAs. Contents:Dispute Settlement in the WTO System:Understanding Non-litigated Disputes in the WTO Dispute Settlement SystemKorea in the GATT/WTO Dispute Settlement System: Legal Battle for Economic DevelopmentPractices and Theoretical Foundations of the Trade Remedy System:Alternative Approach to Causation Analysis in Trade Remedy Investigations: 'Cost of Production' TestThird Country Dumping: Origin, Evolution and ProspectRestructuring the WTO Safeguard Mechanism in The WTO Trade Remedy SystemFoe or Friend of GATT Article XXIV: Diversity in Trade Remedy RulesCountervailing Duty against China: Opening a Pandora's Box in the WTO System?United States — Anti-Dumping Measures on Certain Shrimp and Diamond Sawblades from China: Never Ending Zeroing in the WTO?International Decisions: United States — Definitive Anti-Dumping and Countervailing Duties on Certain Products from ChinaInterrelation between Trade and Finance:Linkages between International Trade and Financial Institutions: IMF, World Bank and WTOWTO Disciplines Under the IMF Program: Congruence or Conflict?Is the Chinese Exchange-rate Regime 'WTO-legal'?Book Review: International Law in Financial Regulation and Monetary AffairsLegal and Economic Analysis of Free Trade Agreements:Dispute Settlement Systems in Asian FTAs: Issues and ProblemsAnalysis of Anti-dumping Use in Free Trade AgreementsLegal Issues for Korea's "Internal Trade" in the WTO System Readership: Researchers, students, and members of the public who are interested in international trade or economic law, international economics and international political economy.
This book provides a political and cultural exploration of the Pusan International Film Festival in South Korea since its inception in 1996. By paying a particular attention to the organizers' use of an Asian regionalization strategy, SooJeong Ahn reveals how the festival staked out a unique and influential position within a rapidly changing global landscape. Very little primary empirical research has been conducted to date on non-Western film festivals, though PIFF and Tokyo and Hong Kong have swiftly grown more exciting and influential as testing grounds for global cinema innovations. The initiation, development and growth of PIFF should be understood as resulting from productive tensions in the festival's efforts to serve local, regional and national constituencies. The book also reflects the complexities of rapid transformation in the South Korean film industry as it has reached out to the global market since the late 1990s. SooJeong Ahn worked for the Pusan International Film Festival between 1998 and 2002 and has completed a Ph.D. on film festivals at the University of Nottingham. Her recent publications include "Re-imagining the Past: Programming South Korean Retrospectives at PIFF," in Film International (Vol. 6, 2008), "Placing South Korean Cinema into Pusan International Film Festival: Programming Strategy in the Global/Local Context," in What a Difference a Region Makes: Cultural Studies and Cultural Industries in North-East Asia (2009); "Re-mapping Asian Cinema: The Tenth Anniversary of PIFF in 2005" in Cinemas, Identities and Beyond (2010).
This book examines Korea’s foreign direct investment policy dynamics and points out the importance of mutual synergy between multinational corporations and their host countries in a win-win framework and the increasing importance of this in a post-pandemic world. A multitude of case studies shows many of the business difficulties foreign investors in Korea face, and how the Foreign Investment Ombudsman has intervened to resolve each one. The book addresses Korea’s challenges and efforts to become a truly preferred FDI destination through active FDI inducement and effective aftercare services. Investigating the ambivalent attitude toward foreign direct investors and foreign migrants in an increasingly globalizing world, the author also analyses the issue of xenophobia. The book demonstrates empirically that appropriate and timely aftercare services can serve as not only a robust facilitator for cross-border investment but also a preventer of undesirable friction between foreign investors and host economies, before disputes become serious legal matters. Finally, it draws policy implications towards a liberal investment order post COVID-19. The book will be of interest to policymakers, investors, and researchers on Korean and East Asian economic studies, FDI promotion, and deregulation for better business environment.
This book studies how the increase of visual representation of mixed-race Koreans formulates a particular racial project in contemporary South Korean media. It explores the moments of ruptures and disjuncture that biracial bodies bring to the formation of neoliberal multiculturalism, a South Korean national racial project that re-aligns racial lines under the nation’s neoliberal transformation. Specifically, Ji-Hyun Ahn examines four televised racial moments that demonstrate particular aspects of neoliberal multiculturalism by demanding distinct ways of re-imagining what it means to be Korean in the contemporary era of globalization. Taking a critical media/cultural studies approach, Ahn engages with materials from archives, the popular press, policy documents, television commercials, and television programs as an inter-textual network that actively negotiates and formulates a new racialized national identity. In doing so, the book provides a rich analysis of the ongoing struggle over racial reconfiguration in South Korean popular media, advancing an emerging scholarly discussion on race as a leading factor of social change in South Korea.
The one who possesses the teacher's Memoranda shall bring peace to the World of the Martial Arts academies ... but what exactly is the Teacher's Memoranda? Volcano High pushes the limits of imagination as super-powered martial arts students battle for supremacy and the possession of the ultimate prize, the teacher's Memoranda!
This monograph introduces recent developments in formation control of distributed-agent systems. Eschewing the traditional concern with the dynamic characteristics of individual agents, the book proposes a treatment that studies the formation control problem in terms of interactions among agents including factors such as sensing topology, communication and actuation topologies, and computations. Keeping pace with recent technological advancements in control, communications, sensing and computation that have begun to bring the applications of distributed-systems theory out of the industrial sphere and into that of day-to-day life, this monograph provides distributed control algorithms for a group of agents that may behave together. Unlike traditional control laws that usually require measurements with respect to a global coordinate frame and communications between a centralized operation center and agents, this book provides control laws that require only relative measurements and communications between agents without interaction with a centralized operator. Since the control algorithms presented in this book do not require any global sensing and any information exchanges with a centralized operation center, they can be realized in a fully distributed way, which significantly reduces the operation and implementation costs of a group of agents. Formation Control will give both students and researchers interested in pursuing this field a good grounding on which to base their work.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study. Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies. The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement. Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
A heartfelt, magical middle grade adventure—inspired by Korean folklore and set in modern-day Seoul—about sisterhood and belonging, perfect for fans of Kelly Yang and Janae Marks. What if an ancient ink brush, oceans away in Korea, could unlock long-buried family secrets? It’s finally summer break, and twelve-year-old Yumi is headed to Korea with her older sister, Minji, for the very first time. She can’t wait to explore the city of Seoul together—but Minji has other plans. The moment they land, Minji ditches Yumi to hang out with their cousins, who are more fashionable, better at soccer, and all-around cooler than Yumi. Lost and alone, Yumi is stuck at home painting with her grandfather. Everything changes when she finds an intriguing ink brush in a neighborhood art shop—and accidentally summons a creature straight out of her grandfather’s retellings of Korean fairy tales. With a new friend by her side and an ink brush that has the power to bring anything she paints to life, Yumi feels unstoppable. From bustling street markets and ancient palaces to riding the subway, Yumi and her friend explore everything Seoul has to offer. But when the magic takes a dark turn, Yumi must dig deep to hear her own voice and protect the family she loves—even if they don’t always understand each other.
In a mountain village in Korea, 1950, the memory of the Japanese occupation has just begun to fade when the farmers hear that the World Army, led by the great American General "Megado" has landed at Inchon.
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