In “And They Shall Be One Flesh”: On the Language of Mystical Union in Judaism, Adam Afterman offers an extensive study of mystical union and embodiment in Judaism. Afterman argues that Philo was the first to articulate the notion of unio mystica in Judaism and is the source of the henōsis mysticism in the later Neoplatonic tradition. The study provides a detailed analysis of the Jewish medieval trends that developed different forms of mystical union and mystical embodiment through the divine name and spirit. The book argues that the development of unitive mysticism in Judaism is the fruit of the creative synthesis of rabbinic Judaism and Hellenistic and Arab philosophy, and a natural outcome of the theological articulation of the idea of monotheism itself.
This best-selling emergency department reference is now in its thoroughly updated Fifth Edition. The foremost authorities provide practical information on over 600 clinical problems in a fast-access two-page outline format that's perfect for on-the-spot consultation during care in the emergency department. Coverage of each disorder includes clinical presentation, pre-hospital, diagnosis, treatment, disposition, and ICD-9 coding. Icons enable practitioners to quickly spot the information they need. This edition provides up-to-date information on topics such as emerging infections, new protocols, and new treatments.
A comprehensive examination that breathes new life into Wordsworth and the ethical concerns that were vital to his nineteenth-century readers. Why read Wordsworth’s poetry—indeed, why read poetry at all? Beyond any pleasure it might give, can it make one a better or more flourishing person? These questions were never far from William Wordsworth’s thoughts. He responded in rich and varied ways, in verse and in prose, in both well-known and more obscure writings. Wordsworth's Ethics is a comprehensive examination of the Romantic poet’s work, delving into his desire to understand the source and scope of our ethical obligations. Adam Potkay finds that Wordsworth consistently rejects the kind of impersonal utilitarianism that was espoused by his contemporaries James Mill and Jeremy Bentham in favor of a view of ethics founded in relationships with particular persons and things. The discussion proceeds chronologically through Wordsworth’s career as a writer—from his juvenilia through his poems of the 1830s and '40s—providing a valuable introduction to the poet’s work. The book will appeal to readers interested in the vital connection between literature and moral philosophy.
“With Supreme Inequality, Adam Cohen has built, brick by brick, an airtight case against the Supreme Court of the last half-century...Cohen’s book is a closing statement in the case against an institution tasked with protecting the vulnerable, which has emboldened the rich and powerful instead.” —Dahlia Lithwick, senior editor, Slate A revelatory examination of the conservative direction of the Supreme Court over the last fifty years. In Supreme Inequality, bestselling author Adam Cohen surveys the most significant Supreme Court rulings since the Nixon era and exposes how, contrary to what Americans like to believe, the Supreme Court does little to protect the rights of the poor and disadvantaged; in fact, it has not been on their side for fifty years. Cohen proves beyond doubt that the modern Court has been one of the leading forces behind the nation’s soaring level of economic inequality, and that an institution revered as a source of fairness has been systematically making America less fair. A triumph of American legal, political, and social history, Supreme Inequality holds to account the highest court in the land and shows how much damage it has done to America’s ideals of equality, democracy, and justice for all.
A History of Securities Law and the Supreme Court explores how the Supreme Court has made (and remade) securities law. It covers the history of the federal securities laws from their inception during the Great Depression, relying on the justices' conference notes, internal memoranda, and correspondence to shed light on how they came to their decisions and drafted their opinions. That history can be divided into five periods that parallel and illustrate key trends of the Court's jurisprudence more generally. The first saw the administration of Franklin Delano Roosevelt--aided by his filling eight seats on the Court-triumph in its efforts to enact the securities laws and establish their constitutional legitimacy. This brought an end to the Court's long-standing hostility to the regulation of business. The arrival of Roosevelt's justices, all committed to social control of finance, ushered in an era of deference to the SEC's expertise that lasted through the 1940s and 1950s. The 1960s brought an era of judicial activism-and further expansion--by the Warren Court, with purpose taking precedence over text in statutory interpretation. The arrival of Lewis F. Powell, Jr. in 1972 brought a sharp reversal. Powell's leadership of the Court in securities law produced a counter-revolution in the field and an end to the SEC's long winning streak at the Court. Powell's retirement in 1987 marked the beginning of the final period of this study. In the absence of ideological consensus or strong leadership, the Court's securities jurisprudence meandered, taking a random walk between expansive and restrictive decisions.
Hope for us has a positive connotation. Yet it was criticized in classical antiquity as a distraction from the present moment, as the occasion for irrational and self-destructive thinking, and as a presumption against the gods. To what extent do arguments against hope today remain useful? If hope sounds to us like a good thing, that reaction stems from a progressive political tradition grounded in the French Revolution, aspects of Romantic literature and the influence of the Abrahamic faiths. Ranging both wide and deep, Adam Potkay examines the cases for and against hope found in literature from antiquity to the present. Drawing imaginatively on several fields and creatively juxtaposing poetry, drama, and novels alongside philosophy, theology and political theory, the author brings continually fresh insights to a subject of perennial interest. This is a bold and illuminating new treatment of a long-running literary debate as complex as it is compelling.
Journeyman's Road offers a bold new vision of where the blues have been in the course of the twentieth century and what they have become at the dawn of the new millennium: a world music rippling with postmodern contradictions. Author Adam Gussow brings a unique perspective to this exploration. Not just an award-winning scholar and memoirist, he is an accomplished blues harmonica player, a Handy award nominee, and veteran of the international club and festival circuit. With this unusual depth of experience, Gussow skillfully places blues literature in dialogue with the music that provokes it, vibrantly articulating a vital American tradition. At the heart of Gussow's story is his own unlikely yet remarkable streetside partnership with Harlem bluesman Sterling Mr. Satan Magee, a musical collaboration marked not just by a series of polarities--black and white, Mississippi and Princeton, hard-won mastery and youthful apprenticeship--but by creative energies that pushed beyond apparent differences to forge new dialogues and new sounds. Undercutting familiar myths about the down-home sources of blues authenticity, Gussow celebrates New York's mongrel blues scene: the artists, the jam sessions, the venues, the street performers, and the eccentrics. At once elegiac and forward-looking, Journeyman's Road offers a collective portrait of the New York subculture struggling with the legacy of 9/11 and healing itself with the blues.
In their third book together, Adam B. Seligman and Robert P. Weller address a seemingly simple question: What counts as the same? Given the myriad differences that divide one individual from another, why do we recognize anyone as somehow sharing a common fate with us? For that matter, how do we live in harmony with groups who may not share the sense of a common fate? Such relationships lie at the heart of the problems of pluralism that increasingly face so much of the world today. Note that "counting as" the same differs from "being" the same. Counting as the same is not an empirical question about how much or how little one person shares with another or one event shares with a previous event. Nothing is actually the same. That is why, as humans, we construct sameness all the time. In the process, of course, we also construct difference. Creating sameness and difference leaves us with the perennial problem of how to live with difference instead of seeing it as a threat. How Things Count as the Same suggests that there are multiple ways in which we can count things as the same, and that each of them fosters different kinds of group dynamics and different sets of benefits and risks for the creation of plural societies. While there might be many ways to understand how people construct sameness, three stand out as especially important and form the focus of the book's analysis: Memory, Mimesis, and Metaphor.
This work investigates the theoretical and cosmological implications of modifying Einstein's theory of general relativity. It explores two classes of modifications to gravity: those in which the graviton is given a small mass, and those in which Lorentz invariance is spontaneously broken. It elucidates the nature of cosmological perturbations in theories of massive bimetric gravity, including a potentially deadly instability. Theories of gravity beyond general relativity could explain why the expansion of the Universe is accelerating, obviating the need for a dark energy, and can also affect the evolution of the early Universe. Next, it investigates the nature of spacetime in massive gravity theories that contain two different spacetime metrics. Lastly, the strongest constraints to date are placed on the size of Lorentz-violating effects in the gravity sector during inflation.
WINNER OF THE LIONEL GELBER PRIZE A NEW YORK TIMES NOTABLE BOOK OF 2018 ONE OF THE ECONOMIST'S BOOKS OF THE YEAR A NEW YORK TIMES CRITICS' TOP BOOK "An intelligent explanation of the mechanisms that produced the crisis and the response to it...One of the great strengths of Tooze's book is to demonstrate the deeply intertwined nature of the European and American financial systems."--The New York Times Book Review From the prizewinning economic historian and author of Shutdown and The Deluge, an eye-opening reinterpretation of the 2008 economic crisis (and its ten-year aftermath) as a global event that directly led to the shockwaves being felt around the world today. We live in a world where dramatic shifts in the domestic and global economy command the headlines, from rollbacks in US banking regulations to tariffs that may ignite international trade wars. But current events have deep roots, and the key to navigating today’s roiling policies lies in the events that started it all—the 2008 economic crisis and its aftermath. Despite initial attempts to downplay the crisis as a local incident, what happened on Wall Street beginning in 2008 was, in fact, a dramatic caesura of global significance that spiraled around the world, from the financial markets of the UK and Europe to the factories and dockyards of Asia, the Middle East, and Latin America, forcing a rearrangement of global governance. With a historian’s eye for detail, connection, and consequence, Adam Tooze brings the story right up to today’s negotiations, actions, and threats—a much-needed perspective on a global catastrophe and its long-term consequences.
This book assesses the forces of social struggle shaping the past and present of the global political economy from the perspective of historical materialism. Based on the philosophy of internal relations, the character of capital is understood in such a way that the ties between the relations of production, state-civil society, and conditions of class struggle can be realised. By conceiving the internal relationship of global capitalism, global war, global crisis as a struggle-driven process, the book provides a novel intervention on debates within theories of 'the international'. Through a set of conceptual reflections, on agency, structure and the role of discourses embedded in the economy, class struggle is established as our point of departure. This involves analysing historical and contemporary themes on the expansion of capitalism through uneven and combined development, the role of the state and geopolitics, and conditions of exploitation and resistance. These conceptual reflections and thematic considerations are then extended in a series of empirical interventions, including a focus on the 'rising powers' of the BRICS, conditions of the 'new imperialism', and the ongoing financial crisis. The book delivers a radically open-ended dialectical consideration of ruptures of resistance within the global political economy.
The sixth edition of this comprehensive yet concise Rosen & Barkin’s 5 Minute Emergency Medicine Consult pulls together up-to-date and evidence-based practice guidelines for easy use in a busy emergency department. In just two brief, bullet-friendly, clutter-free pages, you can quickly decipher the information you need to confirm your diagnosis, order tests, manage treatment and more!
How can cradling, handling, or rubbing a text be said, ethically, to have made something happen? What, as readers or interpreters, may come off in our hands in as we maculate or mark the books we read? For Adam Zachary Newton, reading is anembodied practice wherein “ethics” becomes a matter of tact—in the doubled sense of touch and regard. With the image of the book lying in the hands of its readers as insistent refrain, To Make the Hands Impure cuts a provocative cross-disciplinary swath through classical Jewish texts, modern Jewish philosophy, film and performance, literature, translation, and the material text. Newton explores the ethics of reading through a range of texts, from the Talmud and Midrash to Conrad’s Nostromo and Pascal’s Le Mémorial, from works by Henry Darger and Martin Scorsese to the National September 11 Memorial and a synagogue in Havana, Cuba. In separate chapters, he conducts masterly treatments of Emmanuel Levinas, Mikhail Bakhtin, and Stanley Cavell by emphasizing their performances as readers—a trebled orientation to Talmud, novel, and theater/film. To Make the Hands Impure stages the encounter of literary experience and scriptural traditions—the difficult and the holy—through an ambitious, singular, and innovative approach marked in equal measure by erudition and imaginative daring.
An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines and other drugs. Each of the human metabolic processes will be covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, An Integrated Guide to Human Drug Metabolism is useful for students and researchers needing a reference for interdisciplinary research in drug interactions. Metabolism is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects. - Covers each of the human metabolic processes, employing examples drawn from known metabolic transformations of drugs used clinically - Provides an integrated approach, linking together the science and practice strands of human drug metabolism - Contains questions and answers to assess learning of material and real-life case studies
What is scripture and how does it function? Is there a "scientific" way to understand its meaning? In answer, Adam Wells proposes a phenomenological approach to scripture that radicalizes both phenomenology and its relation to Christianity. By reading the "kenōsis hymn" (Philippians 2:5–11) alongside the work of Edmund Husserl, Wells develops a kenotic reduction that rehabilitates the Husserlian idea of "absolute science" while also disclosing the radical philosophical implications of Paul's "new creation." More broadly, The Manifest and the Revealed pushes the fields of phenomenology and biblical studies forward. The turn to scripture, as a source for theological and philosophical reflection, marks an important advance for the recent "theological turn" in phenomenology. At the same time, by bringing to light the incredible complexity of scripture, phenomenology provides a ay for contemporary biblical studies to exceed its own limits. Wells demonstrates how phenomenology and scripture ultimately illuminate one another in profound and surprising ways.
Nationally representative studies confirm that LGBTQ individuals are at an elevated risk of experiencing intimate partner violence. While many similarities exist between LGBTQ and heterosexual-cisgender intimate partner violence, research has illuminated a variety of unique aspects of LGBTQ intimate partner violence regarding the predictors of perpetration, the specific forms of abuse experienced, barriers to help-seeking for victims, and policy and intervention needs. This is the first book that systematically reviews the literature regarding LGBTQ intimate partner violence, draws key lessons for current practice and policy, and recommends research areas and enhanced methodologies.
The sports industry is more complex than ever before, and succeeding within it now requires an equally dynamic approach. Teams and leagues across many sports face unprecedented competition in worldwide markets as the cost of doing business increases and traditional revenue streams face pressure. In light of these changes, the idea that winning championships is the key to organizational success is misguided. The Sports Strategist: Developing Leaders for a High-Performance Industry reveals which areas in the industry, unlike winning, can be controlled and maximized for consistent success. Aspiring leaders in the sports business will learn how to design identities, manage narratives, and maximize new technologies in order to implement business analytics and build public support. These techniques are vital to creating a successful sports organization that is ready to reap the benefits of winning when it does happen, without having to rely on it when it doesn't. In such a high-performance field, the demand for well-equipped leaders is great, and The Sports Strategist provides the necessary tools and techniques for their success.
Better than Best Practice offers a new way of thinking about classroom practice, professional development, and improving teaching and learning. This companion book and website together offer a selection of rich and realistic video-based case studies, context and narrative, step-by-step guidance through key issues, and commentary and debate from a range of expert contributors. Carefully chosen video clips from primary school literacy lessons show real teachers in a variety of often knotty situations: classroom conversations that take unexpected turns; grappling with assessment; managing disagreements, to name a few. The book explores the educational potential of classroom talk and, in particular, the promise and problems of dialogic pedagogy. With an emphasis on the complexity and ‘messiness’ of teaching, Better than Best Practice considers how to learn from observing and discussing practice in order to develop professional judgment. It offers practical advice on how to organise and facilitate video-based professional development in which teachers share their practice with colleagues in order to learn from one another’s challenges, problems, dilemmas and breakthroughs. This exciting new resource argues that critical discussions of practice, which highlight dilemmas instead of prescribing solutions, help to develop and support thoughtful, flexible, and insightful practitioners: an approach that is better than best practice.
The Annual International Conference on Shi‘i Studies is organised by the Research and Publications Department of The Islamic College, London. The conference aims to provide a broad platform for scholars working in the field of Shi‘i Studies to present their latest research and explore diverse opinions on Shi‘i thought, practice, and heritage. This book comprises a selection of papers from the seventh conference held on 14 May 2022.
If you've ever worked in a fast-paced editorial environment, you know just how frustrating it can be to wait as each member of the team-from writer, to editor, to artist-makes changes to his or her piece of the layout puzzle. With InCopy, you don't have to! The Adobe InCopy Book shows editorial teams how to take control of the copy-fitting process as editors, designers, and writers work simultaneously on the same InDesign CS document. The guide begins with the basics, explaining what InCopy is and how it integrates with InDesign before moving on to describe the interface. The second section provides a feature-by-feature breakdown of how the program works, using simple step-by-step instructions and plenty of screen shots to ease the way. The remainder of the book is devoted to real-world workflows: one in which design trumps copy (that is, the design is created first), one in which copy trumps design (copy is created first), and one in which copy and design are of equal importance.
This book provides a theoretical account of a variety of different communicative aspects of silence and explores new ways of studying socially-motivated language. A research overview shows the influence of related work in the fields of media studies, politics, gender studies, aesthetics and literature. The author argues that in theoretically pragmatic terms, silence can be accounted for by the same principles as those of speech. A later, more applied section of the book explores the power of silencing in politics. A concluding chapter shows the importance of silence beyond linguistics and politics in terms of artistic expression. The approach is intentionally eclectic in order to explore the concept of silence as a rich and
Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed.
This book explores the rise of the aesthetic category of addiction in the nineteenth century, a century that saw the development of an established medical sense of drug addiction. Drugs and the Addiction Aesthetic in Nineteenth-Century Literature focuses especially on formal invention—on the uses of literary patterns for intensified, exploratory engagement with unattained possibility—resulting from literary intersections with addiction discourse. Early chapters consider how Romantics such as Thomas De Quincey created, with regard to drug habit, an idea of habitual craving that related to self-experimenting science and literary exploration; later chapters look at Victorians who drew from similar understandings while devising narratives of repetitive investigation. The authors considered include De Quincey, Percy Shelley, Alfred Tennyson, Christina Rossetti, Charles Dickens, Robert Louis Stevenson, and Marie Corelli.
The Romantic age, though often associated with free erotic expression, was ambivalent about what if anything sex had to do with the public sphere. Late-eighteenth- and early-nineteenth-century British texts often repressed the very sexual energies they claimed to be bringing into the open. The delineation of what could and could not be said and done in the name of physical pleasure was of a piece with the capitalist consecration of the social trust to the individual profit-motive. Both these practices, moreover, presupposed a determinate self with sovereignty over its own interests. Writings from and about some nominally public institutions were thus characterized by privatism—a sexual, economic and ontological withdrawal from otherness. Sexual Privatism in British Romantic Writing: A Public of One explores how this threefold ideology was both propagated and resisted, wittingly and unwittingly, successfully and unsuccessfully, in such Romantic "publics" as rape-law, sodomy-law, adultery-law, high-profile scandals, the population debates, and club-culture. It includes readings of imaginative literature by William Beckford, William Blake, Erasmus Darwin, Mary Hays, Percy Shelley and Mary Wollstonecraft; works of political economy by Jeremy Bentham, William Cobbett, William Godwin, William Hazlitt and Thomas Robert Malthus; as well as contemporary legal treatises, popular journalism and satirical pamphlets.
This book tells the story of a Jewish Studies that hasn’t fully happened—at least not yet. Newton asks what we mean when we say “Jewish Studies”—and when we imagine it not as mere amalgam but as a project. Jewish Studies offers a unique perspective from which to view the horizon of the academic humanities because, although it arrived belatedly, it has spanned a range of disciplinary locations and configurations, from an “origin story” in nineteenth-century historicism and philology, to the emancipatory politics of the Enlightenment, to the ethnicity-driven pluralism of the postwar decades, to more recent configurations within an interdisciplinary cultural studies. The conflicted allegiances with respect to traditions, disciplines, divisions, stakes, and stakeholders represent the structural and historical situation of the field, as it comes into contact with the humanities more broadly. At once a literary and philosophical thinker, Newton deploys a tableau of texts in concert with an ensemble of vivid, elastic tropes not only to theorize Jewish Studies but also to reimagine it as an agent of that potency Jacques Derrida calls “leverage”—a force multiplier for the field’s multiple possibilities. In refiguring a Jewish Studies to come, the book intervenes in a broader discourse about the challenge of professing disciplinary knowledges while promoting transit across their boundaries. Jewish Studies as Counterlife further amplifies Newton’s career-long articulation of the dialogic as the staging ground of ethical encounter.
Christoph Rothmann wrote a treatise on the comet of 1585 shortly after it disappeared. Though it was not printed until 1619, Rothman sent a copy of his treatise in 1586 to Tycho Brahe, decisively influencing the latter's rejection of solid celestial spheres two years later. In his treatise, Rothmann joined the elimination of the solid celestial spheres to his concept of air as the substance filling the cosmos. He based his argument on the absence of refraction and the celestial location of the comet. The treatise also contained clear statements reflecting Rothmann’s adoption of Copernicanism. This first critical edition of the treatise is accompanied by an English translation and a thorough commentary. Some appendices with archival documents illustrate the genesis of Rothmann’s treatise.
Israel’s Lord: YHWH as “Two Powers” in Second Temple Literature addresses the nature of Jewish monotheism in Second Temple literature, advancing an argument that much of the literature reflects the existence of two powers in heaven that are both rightly understood as YHWH. To this end, Wilhite and Winn review various figures such God’s Word, God’s Wisdom, the Angel of the Lord, the Son of Man, and others that bear features closely associate with the God of Israel. Using criteria related to these features they argue that most, though not all, of these figures are rightly identified as the figure who appeared in Israel’s scriptures and was called YHWH. Such a “two powers” paradigm is relevant for understanding early Christian commitments regarding Jesus. The debate about Jesus’ divinity depends in large part on what options were available for the earliest Christians when considering his titles and status. The authors contend that with such a “two powers” paradigm available to the earliest Christians, it should inform any reading of New Testament texts and their varying depictions of Jesus as “Lord.”
Challenges the mainstream understanding of BRICS and US dominance to situate the new global rivalries engulfing capitalism BRICS is a grouping of the five major emerging economies of Brazil, Russia, India, China and South Africa. Volume five in the Democratic Marxism series, BRICS and the New American Imperialism challenges the mainstream understanding of BRICS and US dominance to situate the new global rivalries engulfing capitalism. It offers novel analyses of BRICS in the context of increasing US induced imperial chaos, deepening environmental crisis tendencies (such as climate change and water scarcity), contradictory dynamics inside BRICS countries and growing subaltern resistance. The authors revisit contemporary thinking on imperialism and anti-imperialism, drawing on the work of Rosa Luxemburg, one of the leading theorists after Marx, who attempted to understand the expansionary nature of capitalism from the heartlands to the peripheries. The richness of Luxemburg’s pioneering work inspires most of the volume’s contributors in their analyses of the dangerous contradictions of the contemporary world as well as forms of democratic agency advancing resistance. While various forms of resistance are highlighted, among them water protests, mass worker strikes, anti-corporate campaigning and forms of cultural critique, this volume grapples with the challenge of renewing anti-imperialism beyond the NGO-driven World Social Forum and considers the prospects of a new horizontal political vessel to build global convergence. It also explores the prospects of a Fifth International of Peoples and Workers.
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.
This book is about places - cities, suburbs and towns - and happiness of people living there. Taking an interdisciplinary approach, Okulicz-Kozaryn examines the relations between human happiness and the infrastructure of the places they live. This thought-provoking book argues for the overlooked idea that we are happiest in smaller areas.
If you only have 30 seconds, there is time using this book to make sense of the science behind the seeming vagaries of the weather, the controversies, predictions and forecasts for climate change that shape our day-to-day experiences of the great outdoors. Ever since Aristotle first tried to explain the forces that seem to fall from the heavens, meteorology has opened up the study of weather, and caused disputes over the reasons why seasons change, where precipitation falls, why winds blow and when the sun shines. From halcyon days to hurricanes, super cells to silver linings, global warming to giant hailstones, here is the ultimate guide to a near universal preoccupation: whats the weather like?
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