An integrated presentation of the basic science and clinical applications of anticancer agents Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications. After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year. Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers. Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers. Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.
When the topic of homeschooling comes up, there often seem to be various assumptions as to why we homeschool our children, which are simply wrong, or, at the most, inadequate. Yes, the government schools have bullies; yes, the government schools might be bigger targets for armed shootings; and yes, the government schools (even the ones in good school districts) have kids or teachers who will teach our children language or experiences that we would rather them not learn that early in life (or at all). And while all those things are true and good reasons to educate our children at home, even if those problems were corrected, we—and many other parents—would still be committed to homeschooling our children. Why? The purpose of this book is to answer that question—and to answer it from the Scriptures.
When the topic of homeschooling comes up, there often seem to be various assumptions as to why we homeschool our children, which are simply wrong, or, at the most, inadequate. Yes, the government schools have bullies; yes, the government schools might be bigger targets for armed shootings; and yes, the government schools (even the ones in good school districts) have kids or teachers who will teach our children language or experiences that we would rather them not learn that early in life (or at all). And while all those things are true and good reasons to educate our children at home, even if those problems were corrected, we--and many other parents--would still be committed to homeschooling our children. Why? The purpose of this book is to answer that question--and to answer it from the Scriptures.
SON OF MAN I'm known as: Michael - The Chosen One - Ancient of Days - Elect One - Adam As foretold by the scriptures who liveth amongst you now for these last days in this sacred Book of Adam 45 And so it is written, The first man Adam was made a living soul; the last cAdam was made a dquickening spirit 1 Corinthians 15:45
The best of international bestselling author David Adam's writings. Adam demonstrates a unique blend of modern concerns with a distinctively Celtic approach.
Not Without REASON, Not without CAUSE But that is the Destiny of God's hand at play Being your friend is MY CHOICE But falling in love with you, THAT IS BEYOND MY ABILITY Gazing at your face always makes me want to live for another 1000 YEARS The breath of your being is the LIFE of my existence Adam's Tetralogy: First Books: Adam I ( Encounter ) Second Books: Adam II ( Bangkok I'm in Love ) Third Books: Adam III ( Testament from UTAH ) Fourth Books: Last Chapter ( Adam vs Eve ) Description: I have completed four novels in the ADAM series, with each novel having a different theme but intertwined stories and narratives. I have been working on these manuscripts since 2009, with a total completion time until 2023 of 14 years. My tetralogy, titled ADAM, is a romance fiction genre where the romance novels are set in Indonesia, Australia, Thailand, and America. Here, you will enter a captivating world of romance, transcending continents and cultures without boundaries. Starting from the Encounter in Adam Part I, to the touching story in Bangkok in Adam Part II, the amazing adventure in Utah (Adam Part III), and finally, the inner turmoil between Adam and Eve in Adam Part IV, each page takes you on a profound emotional journey. Enjoy stories of complex and challenging relationships, but also full of courage and hope. Alongside the characters, you will experience the struggle for acceptance and the search for true love, against all cultural and social obstacles. The ADAM tetralogy is not just a romance tale, but also a voice for the diversity of life experiences, providing inspiration and an opportunity to reflect on the true meaning of love and acceptance. It depicts and describes the experiences and struggles of the main characters named Adam and Nicholas James Eliot (Nick), where they are involved in complex, unique, and often highly emotional relationships due to rejection and differences between Eastern and Western cultures that underpin the romance between the main characters, presenting its own set of challenges, especially for those from the East. I strongly believe that my story can open readers' minds to different experiences in life because this story is born from first love with a person named Nicholas James Eliot, who was born and raised in UTAH - the United States. As I write and publish this, the feelings of love still linger. I believe this story will appeal to readers from various backgrounds and captivate many hearts. I hope this novel can provide new experiences and inspiration for readers. Because I believe that every work should have a message to convey, and in this novel, I want to urge readers to continue fighting for our [their] love because we cannot choose to whom we should give our love because love comes from God. I am very pleased if this novel can have a positive impact on its readers and entertain and inspire them. First Synopsis Of Adam (Part I) - Encounter: Upon Adam's return from Australia, he decides to settle down and live with his father in Jakarta, Indonesia. Adam, the only child of a mixed marriage between an Indonesian father and an Australian mother, chooses to continue his studies in Western Indonesia, specifically in the city of Medan, with hopes of finding the right place to his education. Unexpectedly, on this journey, Adam encounters someone who never crossed his mind before, a person named Nicholas. Without plans or preparations, the seeds of love start to blossom between them. However, love doesn't always end in happiness. They fall deeply in love and share profound feelings for each other. Fear, worry, and even tears become part of the challenges they must confront. This compels them to separate for a period of 10 long years, resulting in profound disappointment and trauma as they search for the true meaning of love. LOVING you IS BEAUTY
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