The last century has seen radical social changes in Ireland, which have impacted all aspects of local life but none more so than traditional Irish music, an increasingly important identity marker both in Ireland and abroad. The author focuses on a small village in County Clare, which became a kind of pilgrimage site for those interested in experiencing traditional music. He begins by tracing its historical development from the days prior to the influx of visitors, through a period called "the Revival," in which traditional Irish music was revitalized and transformed, to the modern period, which is dominated by tourism. A large number of incomers, locally known as "blow-ins," have moved to the area, and the traditional Irish music is now largely performed and passed on by them. This fine-grained ethnographic study explores the commercialization of music and culture, the touristic consolidation and consumption of "place," and offers a critique of the trope of "authenticity," all in a setting of dramatic social change in which the movement of people is constant.
Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.
In the eighteenth century, audiences in Great Britain understood the term ’slavery’ to refer to a range of physical and metaphysical conditions beyond the transatlantic slave trade. Literary representations of slavery encompassed tales of Barbary captivity, the ’exotic’ slaving practices of the Ottoman Empire, the political enslavement practiced by government or church, and even the harsh life of servants under a cruel master. Arguing that literary and cultural studies have focused too narrowly on slavery as a term that refers almost exclusively to the race-based chattel enslavement of sub-Saharan Africans transported to the New World, the contributors suggest that these analyses foreclose deeper discussion of other associations of the term. They suggest that the term slavery became a powerful rhetorical device for helping British audiences gain a new perspective on their own position with respect to their government and the global sphere. Far from eliding the real and important differences between slave systems operating in the Atlantic world, this collection is a starting point for understanding how slavery as a concept came to encompass many forms of unfree labor and metaphorical bondage precisely because of the power of association.
This book explores how professional and organisational cultures influence global public-private partnerships, which form a key element of global governance. Using case studies, the partnerships of three international government organisations – the International Telecommunication Union, Interpol and the International Centre for the Study of the Preservation and Restoration of Cultural Property – illustrate how partnerships are formed and operate in accordance with the accepted cultural beliefs and values associated with both profession and organisation. In brief, engineers create partnerships they are comfortable with, which are different in form and operation to those of police, which also differ from those of the conservator. This book will appeal to scholars of international relations, global governance, organisational studies and public administration. It also conveys lessons for professionals at the international level in international government organisations, business and civil society who engage in, or want to engage in global public-private partnerships.
This book is an introduction to complex systems thinking at the global governance level. It offers concepts, tools, and ways of thinking about how systems change that can be applied to the most wicked problems facing the world today. More than an abstract argument for complexity theory, the book offers a targeted critique of today’s highest-profile proposals for improving the governance of our environment, security, finance, health, and digital space. It suggests that we should spend less effort and resources on upgrading existing institutions, and more on understanding how they (and we) relate to each other. The volume will be essential reading for public policymakers, NGOs and think tanks, foreign policy experts, government officials, and global decision-makers.
This compelling book examines the price-based revolution in investing, showing how research over recent decades has reinvented technical analysis. The authors discuss the major groups of price-based strategies, considering their theoretical motivation, individual and combined implementation, and back-tested results when applied to investment across country stock markets. Containing a comprehensive sample of performance data, taken from 24 major developed markets around the world and ranging over the last 25 years, the authors construct practical portfolios and display their performance—ensuring the book is not only academically rigorous, but practically applicable too. This is a highly useful volume that will be of relevance to researchers and students working in the field of price-based investing, as well as individual investors, fund pickers, market analysts, fund managers, pension fund consultants, hedge fund portfolio managers, endowment chief investment officers, futures traders, and family office investors.
This book demonstrates how quantitative country-level investment strategies can be successfully employed to manage money in international markets. It offers a range of state-of-the-art quantitative strategies, describing their theoretical bases, implementation details, and performance in over 70 countries between 1995 and 2015. International diversification has long been a key to stable investing. However, the increased integration and openness of global financial markets has led to rising correlations between stock market returns in particular countries, driving down the benefits of diversification and increasing the importance of country selection strategies as part of an investment process. Zaremba and Shemer explain the efficiency of quantitative investing, which captures huge amounts of data of limited scope very quickly. In the traditional approach, this data compilation is an immense undertaking, limited in scope and vulnerable to behavioral errors, but this can be overcome with the help of a new paradigm of quantitative investment at the country level. Quantitative country asset allocation can be efficiently accomplished by using wealth insights that have been generated in the academic literature, discovering many anomalies and regular patterns in asset prices. Armed with this information, investors and managers can process large amounts of data more efficiently when deciding to invest in ETFs, index funds, or futures markets.
When close to a continuous phase transition, many physical systems can usefully be mapped to ensembles of fluctuating loops, which might represent for example polymer rings, or line defects in a lattice magnet, or worldlines of quantum particles. 'Loop models' provide a unifying geometric language for problems of this kind. This thesis aims to extend this language in two directions. The first part of the thesis tackles ensembles of loops in three dimensions, and relates them to the statistical properties of line defects in disordered media and to critical phenomena in two-dimensional quantum magnets. The second part concerns two-dimensional loop models that lie outside the standard paradigms: new types of critical point are found, and new results given for the universal properties of polymer collapse transitions in two dimensions. All of these problems are shown to be related to sigma models on complex or real projective space, CP^{n−1} or RP^{n−1} -- in some cases in a 'replica' limit -- and this thesis is also an in-depth investigation of critical behaviour in these field theories.
Used by generations of physicians who encounter patients with dermatological diseases, Lever’s Dermatopathology: Histopathology of the Skin comprehensively covers skin disease in which histopathology plays an important role in diagnosis. The updated 12th Edition, edited by Drs. David E. Elder, Rosalie Elenitsas, George F. Murphy, Misha Rosenbach, Adam I. Rubin, John T. Seykora, and Xiaowei Xu, maintains the proven, clinicopathologic classification of cutaneous disease while incorporating a “primer” on pattern-algorithm diagnosis. It features larger images throughout, as well as thoroughly revised content with new diseases and new information on pathophysiology and molecular pathogenesis—all in an easy-to-navigate, highly readable format.
How close are we to defeating cancer? A “calming and illuminating” blend of memoir and medical history (Janet Maslin, The New York Times). When his father was diagnosed with cancer, documentary filmmaker Adam Wishart couldn’t find a book that clearly answered his most basic questions: What was the disease and how did it take hold? What is it about cancer’s biology that makes it hard to eradicate? And most importantly, are we on the way to a cure? One in Three is both a son’s personal story and a journalistic take on cancer’s history, outlining the encouraging story of science’s progress in changing the outlook on cancer from a disease we die from to one we live with. Covering the discovery of the disease, its treatment, and its prevention, this is a story of both hardship and hope, and a helpful companion for anyone dealing with this all too common illness as a patient, a loved one, or a caregiver. “An engaging presentation of facts reported with the cool detachment of a professional journalist interspersed with the raw feelings of a son recording the progress of his father’s fatal illness, what’s right and wrong within the medical community, and the emotional toll on everyone involved with the father and son’s journey.” —Booklist “Fascinating.” —San Francisco Chronicle “Makes abstract science accessible and dignifies a human story with the insights of medicine.” —Andrew Solomon, New York Times–bestselling and National Book Award–winning author of Far from the Tree
This book describes the physical operation of the Tunnel Field-effect Transistor (TFET) and circuits built with this device. Whereas the majority of publications on TFETs describe in detail the device, its characteristics, variants and performance, this will be the first book addressing TFET integrated circuits (TFET ICs). The authors describe the peculiarities of TFET ICs and their differences with MOSFETs. They also develop and analyze a number of logic circuits and memories. The discussion also includes complex circuits combining CMOS and TFET, as well as a potential fabrication process in Silicon.
This thesis is a tour-de-force combination of analytic and computational results clarifying and resolving important questions about the nature of quantum phase transitions in one- and two-dimensional magnetic systems. The author presents a comprehensive study of a low-dimensional spin-half quantum antiferromagnet (the J-Q model) in the presence of a magnetic field in both one and two dimensions, demonstrating the causes of metamagnetism in such systems and providing direct evidence of fractionalized excitations near the deconfined quantum critical point. In addition to describing significant new research results, this thesis also provides the non-expert with a clear understanding of the nature and importance of computational physics and its role in condensed matter physics as well as the nature of phase transitions, both classical and quantum. It also contains an elegant and detailed but accessible summary of the methods used in the thesis—exact diagonalization, Monte Carlo, quantum Monte Carlo and the stochastic series expansion—that will serve as a valuable pedagogical introduction to students beginning in this field.
How poor migrants shape city politics during urbanization As the Global South rapidly urbanizes, millions of people have migrated from the countryside to urban slums, which now house one billion people worldwide. The transformative potential of urbanization hinges on whether and how poor migrants are integrated into city politics. Popular and scholarly accounts paint migrant slums as exhausted by dispossession, subdued by local dons, bought off by wily politicians, or polarized by ethnic appeals. Migrants and Machine Politics shows how slum residents in India routinely defy such portrayals, actively constructing and wielding political machine networks to demand important, albeit imperfect, representation and responsiveness within the country’s expanding cities. Drawing on years of pioneering fieldwork in India’s slums, including ethnographic observation, interviews, surveys, and experiments, Adam Michael Auerbach and Tariq Thachil reveal how migrants harness forces of political competition—as residents, voters, community leaders, and party workers—to sow unexpected seeds of accountability within city politics. This multifaceted agency provokes new questions about how political networks form during urbanization. In answering these questions, this book overturns longstanding assumptions about how political machines exploit the urban poor to stifle competition, foster ethnic favoritism, and entrench vote buying. By documenting how poor migrants actively shape urban politics in counterintuitive ways, Migrants and Machine Politics sheds new light on the political consequences of urbanization across India and the Global South.
In this provocative book, Adam Harmes reveals how only effective political globalization can balance and hold in check the extremes of global corporations. Free trade agreements and economic globalization have created a gap between global transnational corporations and governments mired within national boundaries. Large corporations are now operating “above the law.” Return of the State takes us into the corporate boardrooms, government departments and international organizations where a new global compromise is being forged. It argues that political globalization is both necessary and likely, revealing what it will involve, and what it will mean for corporations, civil society and private citizens around the world. Return of the State is well-researched, hard hitting, controversial and prescient.
Rural Development is a textbook that critically examines economic, social and cultural aspects of rural development efforts both in the global north and in the global south. By consistently using examples from the north and the south the book highlights similarities of processes as well as differences in contexts. The authors’ knowledge of Afghanistan and Sweden respectively creates a core for the discussions which are complemented with a wide range of other empirical examples. Rural Development is divided into nine chapters, each with a thematic focus, ranging from concepts and theories through rural livelihoods and natural resources to discussions on policy and processes of change. The book sees rural development as a multi-level, multi-actor and multi-faceted subject area that needs multidisciplinary perspectives both to support it and to analyse it. Throughout the book examples of rural development interventions are discussed using analytical concepts such as power, discourse, consequences and context to grasp rural development as practices that are more than what is presented in policy documents. The book is written in a way that makes it accessible for undergraduates while at the same time caters for the kind of deeper reading used by master students and Ph.D.’s. Every chapter is linked to discussion questions as well as suggested further readings and useful websites.
This book explains the increasing incidences and normalisation of Islamophobia, by analysing the role of signifiers of free speech, censorship, and fatwa during the Satanic Verses affair in problematising the figure of the Muslim. Ismail Patel develops the notion of Islamophobia not as a continuation of the antagonistic relation from the British Empire but as a postcolonial reformulation of the figure of the Muslim. The book views Islamophobia studies as a paradigm, engages in the debate of Islamophobia as a global phenomenon, investigates the contestation over its definition and challenges the view of Islamophobia as a reserve of the far-right. It assesses the debate around the concept of identity and shows how the colonised figure of the Muslim provided significance in constructing British imperial identity. Providing a decolonial, counter-Islamophobia approach that challenges Britishness’ exclusionary white symbolic content, the book calls for a liberating idea of Britishness that promotes a post-racist rather than a post-race society. Theoretically rich in analysis, this book will contribute to discussions of identity formation, Britishness, Islamophobia and counter-Islamophobia. It will be of use to students and researchers across history, politics, sociology, cultural studies, literary studies, and anthropology.
This book’s great service is that it challenges us to consider the ways in which our institutions and systems, and the assumptions, positions and divisions that undergird them, leave us ill prepared for the next crisis."—Robert Rubin, The New York Times Book Review "Full of valuable insight and telling details, this may well be the best thing to read if you want to know what happened in 2020." --Paul Krugman, New York Review of Books Deftly weaving finance, politics, business, and the global human experience into one tight narrative, a tour-de-force account of 2020, the year that changed everything--from the acclaimed author of Crashed. The shocks of 2020 have been great and small, disrupting the world economy, international relations and the daily lives of virtually everyone on the planet. Never before has the entire world economy contracted by 20 percent in a matter of weeks nor in the historic record of modern capitalism has there been a moment in which 95 percent of the world's economies were suffering all at the same time. Across the world hundreds of millions have lost their jobs. And over it all looms the specter of pandemic, and death. Adam Tooze, whose last book was universally lauded for guiding us coherently through the chaos of the 2008 crash, now brings his bravura analytical and narrative skills to a panoramic and synthetic overview of our current crisis. By focusing on finance and business, he sets the pandemic story in a frame that casts a sobering new light on how unprepared the world was to fight the crisis, and how deep the ruptures in our way of living and doing business are. The virus has attacked the economy with as much ferocity as it has our health, and there is no vaccine arriving to address that. Tooze's special gift is to show how social organization, political interests, and economic policy interact with devastating human consequences, from your local hospital to the World Bank. He moves fluidly from the impact of currency fluctuations to the decimation of institutions--such as health-care systems, schools, and social services--in the name of efficiency. He starkly analyzes what happened when the pandemic collided with domestic politics (China's party conferences; the American elections), what the unintended consequences of the vaccine race might be, and the role climate change played in the pandemic. Finally, he proves how no unilateral declaration of 'independence" or isolation can extricate any modern country from the global web of travel, goods, services, and finance.
As our understanding of mobile genetic elements continues to grow we are gaining a deeper appreciation of their importance in shaping the bacterial genome and in the properties they confer to their bacterial hosts. These include, but are by no means limited to, resistance to antibiotics, and heavy metals, toxin production and increased virulence, production of antibiotics and the ability to utilize a diverse range of metabolic substrates. We are also gaining an understanding of diversity of these elements and their interactions with each other; a property which continually complicates any attempt to classify them. We are learning more about the molecular mechanisms by which they translocate to new genomic sites both within genomes and between different bacteria. This book provides a timely, state of the art update on the properties of an important selection of different bacterial integrative mobile genetic elements and the myriad of different ways in which they move and influence the biology of the host bacterium. The chapters are all written by authors who have undertaken pioneering work in their respective fields, making this book vital reading for all who are interested in the biology of bacteria and the mobile elements they carry.
This manual gives information on the causative organisms, epidemiology and clinical features of all important childhood infections. It includes guidance on the clinical management of the infections and on steps to be taken to prevent future cases.
This book assesses and evaluates the decision-making behavior of United States presidents and their chief advisers from Roosevelt to Kennedy pertaining to China. Seeking to dispel with the notion that each administration sought policy outcomes on the basis of a rational decision-making model, Bartley highlights the contradictions of adopted presidential decision-making processes and the nature of domestic politics as playing prejudicial and debilitating roles. The book demonstrates that elite decision-making processes interacted with assumptions made about Chinese behavior, interests, and attitudes only superficially and in some cases not at all. Misinformation and misperception were the natural outcomes. Reinforced by the politics of McCarthyism at home, intellectual debate on China policy was squashed, parochialism and nuance were shunned, and information was closed off. Ultimately, a divorce between the norm of behavior and the search for rational policy was registered in each administration. The net result was a lasting and destructive cognitive dissonance: to fit expectations of a China reality constructed, information was ignored, overlooked, and distorted. Offering new insights into the China policies of consecutive administrations from 1941 to 1963, this volume will be of great interest to scholars and students of American foreign policy, security studies, and international relations.
This first-of-its-kind book describes the roles of conventional medicine, complementary therapies, and natural alternative therapies in the treatment of gynecological disorders. The book gives practitioners much-needed information on how complementary and alternative therapies work and how they interact with conventional medicines. The chapters are organized by disease and each includes information on etiology, diagnosis, differential diagnosis, the conventional therapy (drug, procedure, etc.), complementary therapy (acupuncture, chiropractic and manipulative therapy, biofeedback, etc.), and alternative therapy (nutrition, herbal, homeopathy). The sections on complementary and alternative therapies explain what the therapies are and describe the postulated mechanisms of action.
This study investigates the philosophical and political significance of Judaism in the intellectual life of seventeenth and eighteenth century Europe. Adam Sutcliffe shows how the widespread and enthusiastic fascination with Judaism prevalent around 1650 was largely eclipsed a century later by attitudes of dismissal and disdain. He argues that Judaism was uniquely difficult for Enlightenment thinkers to account for, and that their intense responses, both negative and positive, to Jewish topics are central to an understanding of the underlying ambiguities of the Enlightenment itself. Judaism and the Jews were a limit case, a destabilising challenge, and a constant test for Enlightenment rationalism. Erudite and highly broad-ranging in its sources, and yet extremely accessible in its argument, Judaism and Enlightenment is a major contribution to the history of European ideas, of interest to scholars of Jewish history and to those working on the Enlightenment, toleration and the emergence of modernity itself.
An overview of the pollination in Australian rainforests, especially subtropical rainforests. It also examines the plant-pollinator relationships found in rainforests worldwide.
Like earlier editions, the Third Edition of Tourists and Tourism is organized for use in the classroom. While several classic and popular articles from the second edition have been retained, three-quarters are new and cover important areas in tourism studies such as dark tourism, medical tourism, nonvisual sensory experiences of tourism, and tourism as performance. Several address issues that directly relate to the student experience, including study abroad, service learning, social media, and the ethics of travel. Articles vary in length and style; some provide deeper context, while others are designed to spark debate in the classroom. Finally, an introduction to the use of film in teaching about tourism and a link to an important film resource are provided.
This task-based, visual guide uses step-by-step instructions and hundreds of full-color screenshots to teach beginning and intermediate users how to make the most out of their digital photos with the new iPhoto 08.
The last century has seen radical social changes in Ireland, which have impacted all aspects of local life but none more so than traditional Irish music, an increasingly important identity marker both in Ireland and abroad. The author focuses on a small village in County Clare, which became a kind of pilgrimage site for those interested in experiencing traditional music. He begins by tracing its historical development from the days prior to the influx of visitors, through a period called "the Revival," in which traditional Irish music was revitalized and transformed, to the modern period, which is dominated by tourism. A large number of incomers, locally known as "blow-ins," have moved to the area, and the traditional Irish music is now largely performed and passed on by them. This fine-grained ethnographic study explores the commercialization of music and culture, the touristic consolidation and consumption of “place,” and offers a critique of the trope of "authenticity," all in a setting of dramatic social change in which the movement of people is constant.
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