Modern biology is increasingly focused on the role of repetitive anatomical structures in the embryological construction of organisms. The discovery of the homeobox (Hox) genes by Edward Lewis in 1978 ushered in a series of stunning revelations such as the fundamental commonality of insect segments and mammalian vertebrae - a wild and ridiculed idea first proposed by Etienne Geoffroy Saint-Hilaire in 1822 that has now been proven correct. Axial Character Seriation in Mammals is an unabridged edition of the 1986 Harvard University PhD Thesis of Aaron G. Filler, MD, PhD that pioneered our modern reassessment of mammalian vertebrae in the light of the new homeotic biology. As Dr. Filler points out in fascinating detail, the leading explanations of similarity among animals before Darwin were arrayed around the vertebrae of the spine in works by Sir Richard Owen, Johann Wolfgang Goethe and Geoffroy Saint-Hilaire. This was the theoretical structure that was overturned and demolished by Darwin's ideas about similarity due to common descent. In a stunning reversal, modern homeotic genetics has shown that repeating structures are indeed critical to understanding animal similarity. This work is the first study of the modern era that views vertebrae as a key to unlocking the way in which Nature has organized repeating biological structures. For the 150 years since the Great Academy Debate of 1830 appeared to demolish Geoffroy Saint-Hilaire's ideas, vertebrae have been seen as no more than some bones in Vertebrate animals that are involved in support and locomotion. Axial Character Seriation in Mammals, however, explores the fascinating traces of how the morphogenetic genes sculpt and organize serially repeating structures, thus re-establishing the vertebrae as a legitimate and compelling subject of modern science.
“A neurosurgeon and evolutionary scholar presents a bold new theory on the early origins of the hominiform (human-like) primates . . . Thought-provoking.” —Kirkus Reviews Drawing on such diverse antecedents as history, myth, and religion, as well as modern developments in biology and genetics, the author bravely questions and rejects the reigning scientific orthodoxy and shows how humans and apes may have had a common upright ancestor—an upright ape that walked on two legs much as we do now. “Fuller’s book is very interesting and well worth reading. His evaluation of this mid lumbar vertebrae fossil may well become the watershed opinion guiding future understanding of evolution. I highly recommend The Upright Ape.” —Compulsive Reader
An internationally recognized expert in nerve and spinal surgery covers everything a back patient needs to know in deciding whether or not to have surgery, discussing the various types of surgery available, the risks of surgery, and the options one may have.
This new edition of Do You Really Need Back Surgery? provides a wide range of information for back and neck pain sufferers - ranging from "Pilates to Pedicle Screws." It is written by a world famous neurosurgical spine expert, who is also a widely published author, and contains answers to questions that your doctors often don't have time to discuss. It is an essential manual for every neck or back pain sufferer.
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