This book presents comprehensive coverage of linear control systems along with an introduction to digital control systems. It is designed for undergraduate courses in control systems taught in departments of electrical engineering, electronics and instrumentation, electronics and communication, instrumentation and control, and computer science and engineering. The text discusses the important concepts of control systems, transfer functions and system components. It describes system stability, employing the Hurwitz–Routh stability criterion, root locus technique, Bode plot, and polar and Nyquist plots. In addition, this student-friendly book features in-depth coverage of controllers, compensators, state-space modelling and discrete time systems. KEY FEATURES •Includes a brief tutorial on MATLAB in an appendix to help students learn how to use it for the analysis and design of control systems. •Provides an abundance of worked-out examples and review questions culled from university examination papers. •Gives answers to selected chapter-end questions at the end of the book.
The third edition of this text focuses on the basic concepts of control systems as before. It presents them in a succinct style and with about 400 worked-out examples. The study of control systems basically entails a knowledge of different kinds of systems that are presented via their transfer functions in the time domain and frequency domain. A major part of this study involves a knowledge of stability of systems in those domains. But then, a knowledge of study of multiple input multiple output (MIMO) systems as well as digital systems is also necessary. All these have been dealt with in lucid, student-friendly manner and with the assumption that the student has only HS-level mathematics background. NEW TO THIS EDITION • Quick reading guide. • Introduction of relevant mathematics wherever needed. • Emphasis on MCQs, which demand knowledge of intricate concepts. • Graphs and diagrams to illustrate concepts. TARGET AUDIENCE • B.Tech Electrical Engineering • B.Tech Electronics and Communication Engineering • B.Tech Instrumentation and Control Engineering • B.Tech Applied Electronics and Instrumentation Engineering • B.Tech Computer Science and Engineering
Ideal for college students in intermediate finance courses, this book uniquely applies mathematical formulas to teach the underpinnings of financial and lending decisions, covering common applications in real estate, capital budgeting, and commercial loans. An updated and expanded version of the time-honored classic text on financial math, this book provides, in one place, a complete and practical treatment of the four primary venues for finance: commercial lending, financial formulas, mortgage lending, and resource allocation or capital budgeting techniques. With an emphasis on understanding the principles involved rather than blind reliance on formulas, the book provides rigorous and thorough explanations of the mathematical calculations used in determining the time value of money, valuation of loans by commercial banks, valuation of mortgages, and the cost of capital and capital budgeting techniques for single as well as mutually exclusive projects. This new edition devotes an entire chapter to a method of evaluating mutually exclusive projects without resorting to any imposed conditions. Two chapters not found in the previous edition address special topics in finance, including a novel and innovative way to approach amortization tables and the time value of money for cash flows when they increase geometrically or arithmetically. This new edition also features helpful how-to sections on Excel applications at the end of each appropriate chapter.
Primarily intended as a textbook for undergraduate courses in applied electronics and instrumentation engineering, instrumentation and control engineering, electrical and electronics engineering and electronics and telecommunication engineering, this student-friendly book provides an in-depth coverage of transducers. Organised in 12 chapters, the book • presents a comprehensive classification of transducers based on common properties such as mechanical, resistive, inductive, capacitive, piezoelectric, magnetic, fibre-optic, ultrasonic and electrochemical; • discusses the general principles of each group, presenting their applications in sensing physical quantities such as pressure, temperature and so on; • outlines the distinguishing features of transducers and elaborates on modern sensors based on optical fibres (intensity modulated, phase modulated and spectrally modulated sensors such as Bragg grating, Fabry–Pérot interferometer, Brillouin scattering sensor) and sensors based on surface acoustic wave; and • contains numerous solved examples and review questions that illustrate the application of theory to reinforce the concepts.
The fourth edition of this highly readable and well-received book presents the subject of measurement and instrumentation systems as an integrated and coherent text suitable for a one-semester course for undergraduate students of Instrumentation Engineering, as well as for instrumentation course/paper for Electrical/Electronics disciplines. Modern scientific world requires an increasing number of complex measurements and instruments. The subject matter of this well-planned text is designed to ensure that the students gain a thorough understanding of the concepts and principles of measurement of physical quantities and the related transducers and instruments. This edition retains all the features of its previous editions viz. plenty of worked-out examples, review questions culled from examination papers of various universities for practice and the solutions to numerical problems and other additional information in appendices. NEW TO THIS EDITION Besides the inclusion of a new chapter on Hazardous Areas and Instrumentation(Chapter 15), various new sections have been added and existing sections modified in the following chapters: Chapter 3 Linearisation and Spline interpolation Chapter 5 Classifications of transducers, Hall effect, Piezoresistivity, Surface acoustic waves, Optical effects (This chapter has been thoroughly modified) Chapter 6 Proximitys sensors Chapter 8 Hall effect and Saw transducers Chapter 9 Proving ring, Prony brake, Industrial weighing systems, Tachometers Chapter 10 ITS-90, SAW thermometer Chapter 12 Glass gauge, Level switches, Zero suppression and Zero elevation, Level switches Chapter 13 The section on ISFET has been modified substantially
Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design. This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design. This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.
The development of HIV protease inhibitors (PIs) and their inclusion in highly active antiretroviral therapies (HAARTs) marked the beginning of a treatment breakthrough in the management of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). The HAART treatment regimen can cut HIV viral load to undetectable levels. Nonetheless, the rapid emergence of HIV drug resistance has continued to seriously compromise long-term treatment options for HIV-infected patients. Our structure-based design strategy to develop PIs that specifically target the enzyme's backbone atoms has resulted in a number of very potent inhibitors with superior drug resistance profiles. Of particular note, our development of stereochemically defined bis(tetrahydrofuranyl) urethane as a high-affinity P2 ligand has led to the development of exceedingly potent inhibitors. One of these inhibitors, darunavir, has shown exceptional potency against the HIV-1 virus and superior activity against multi-PI-resistant viral strains. Our backbone binding strategy was corroborated with detailed crystal structure analyses of darunavir-bound protease complexes which revealed a series of conserved interactions between the inhibitor and key backbone atoms of HIV-1 protease. Darunavir first received accelerated US Food and Drug Administration approval in 2006 for highly treatment-experienced patients with little therapeutic options. It has now become a leading PI in the fight against HIV infection and drug resistance.
Primarily intended as a textbook for undergraduate courses in applied electronics and instrumentation engineering, instrumentation and control engineering, electrical and electronics engineering and electronics and telecommunication engineering, this student-friendly book provides an in-depth coverage of transducers. Organised in 12 chapters, the book • presents a comprehensive classification of transducers based on common properties such as mechanical, resistive, inductive, capacitive, piezoelectric, magnetic, fibre-optic, ultrasonic and electrochemical; • discusses the general principles of each group, presenting their applications in sensing physical quantities such as pressure, temperature and so on; • outlines the distinguishing features of transducers and elaborates on modern sensors based on optical fibres (intensity modulated, phase modulated and spectrally modulated sensors such as Bragg grating, Fabry–Pérot interferometer, Brillouin scattering sensor) and sensors based on surface acoustic wave; and • contains numerous solved examples and review questions that illustrate the application of theory to reinforce the concepts.
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