Over the past 30 years many significant advances have been made in the management of a number of disseminated malignant diseases. The prognosis for diseases such as childhood leukaemia, choriocarcinoma and Hodgkin's disease has gradually been transformed as better anti tumour agents have become available and their clinical use has been refined. During the past 10 years the advent of new agents, particularly cisplatin, bleomycin and the podophyllotoxins, has allowed the cure of disseminated testicular tumours. This degree of success has not, however, been achieved in the case of a number of other common cancers. Ovarian carcinoma is tantalisingly chemo-sensitive and although there are long term survivors from disseminated disease, these are only a small proportion of the total. Breast cancer, although "sensitive" to a multitude of drugs appears to have yielded neither survival benefit, nor cure to the efforts of therapists, while tumours such as those of the colon remain stubbornly unresponsive. Against this backcloth it is apparent that additional more selective treatments are needed if further impact is to be made on the problem of cancer. The development of such agents requires the integration of a multidisciplinary effort encompassing the fields of chemistry, biology and medicine. This symposium provided a forum for clinical and preclinical sCientists, where current aspects of cancer treatment were reviewed and approaches to the development of a new generation of more selective anticancer drugs discussed.
The aim of this book is to help create new feedstuffs for poultry and farm animals from the agro-industry and to mobilize the neglected waste as a feedstuff to lower the price of animal products such as eggs, white and red meat, milk, etc. Furthermore, this book aims to contribute to the campaign against hunger in the developing world and to reduce the competition between animals and human beings for cereals and pulses. Accordingly the global pollution problem will be reduced. This book will be of great interest to all those involved in the animal feed and poultry industries, in agricultural universities, and in research establishments where animal nutrition is studied and taught.
First published in 1900, this is the second of two volumes of the magnum opus from pioneer assyriologist and linguist Rev. Archibald Sayce and continues directly from the first, providing an introduction to linguistic roots, inflectional families of speech, agglutinative, incorporating, polysynthetic and isolating languages, comparative mythology, the science of religion, the origin of language and the relation of language to ethnology, logic and education. In it, Sayce was the first to emphasize the principle of partial assimilation and the linguistic principle of analogy. This 4th edition, ten years after the first, reflected on the limitations of science revealed since 1890, in an era when languages, like other humanities subjects, still idealised scientific approaches. Archibald Henry Sayce was one of the greatest comparative linguists of the time, being proficient in Accadian, Arabic, Cuneiform, Chinese, Egyptian, Greek, Hebrew, Hittite, Japanese, Latin, Persian, Phoenician, Sanscrit and Sumerian. He had a good knowledge of every Semitic and Indo-European language and could write good prose in at least twenty languages. Sayce's first major contribution to scholarship was a highly significant translation of an Accadian seal, a 'bilingual text' from which to translate cuneiform, similar to the Rosetta Stone. Here then, no doubt, the reader learns from a master of comparative linguistics.
Samuel Palmer (1805–1881) was one of the leading British landscape painters of the nineteenth century. Inspired by his mentor, the artist and poet William Blake, Palmer brought a new spiritual intensity to his romantic depictions of nature. A Memoir of Samuel Palmer contains the first biography of the artist, written by his son A. H. Palmer; a critical appreciation of Palmer by Pre-Raphaelite artist and critic F. G. Stephens, which provides a deeply personal look at the painter as well as insight into the reception of his art during the Victorian era; and an autobiographical letter by Palmer himself.
Over the past 30 years many significant advances have been made in the management of a number of disseminated malignant diseases. The prognosis for diseases such as childhood leukaemia, choriocarcinoma and Hodgkin's disease has gradually been transformed as better anti tumour agents have become available and their clinical use has been refined. During the past 10 years the advent of new agents, particularly cisplatin, bleomycin and the podophyllotoxins, has allowed the cure of disseminated testicular tumours. This degree of success has not, however, been achieved in the case of a number of other common cancers. Ovarian carcinoma is tantalisingly chemo-sensitive and although there are long term survivors from disseminated disease, these are only a small proportion of the total. Breast cancer, although "sensitive" to a multitude of drugs appears to have yielded neither survival benefit, nor cure to the efforts of therapists, while tumours such as those of the colon remain stubbornly unresponsive. Against this backcloth it is apparent that additional more selective treatments are needed if further impact is to be made on the problem of cancer. The development of such agents requires the integration of a multidisciplinary effort encompassing the fields of chemistry, biology and medicine. This symposium provided a forum for clinical and preclinical sCientists, where current aspects of cancer treatment were reviewed and approaches to the development of a new generation of more selective anticancer drugs discussed.
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