Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
This book focuses on corrosion and microbial corrosion, providing solutions for these problems based on nanotechnology and nanobiotechnology. It introduces the causes, consequences, cost and control of corrosion processes. It gives a particular emphasis on microbial corrosion of steel and other metals in oil, gas and shipping industries. The book presents the materials vulnerable to such kind of corrosion, and the use of nanomaterials to control it.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more.
Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and health. The final section focuses on CK2 and cancer, looking at the impacts of the kinase on neoplastic development and its rapidly developing role as a therapeutic agent. With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Editor Lorenzo A. Pinna is Professor in the Department of Biomedical Sciences at the University of Padua, Padua, Italy. Also Published in the Wiley-IUBMB Series on Biochemistry and Molecular Biology: Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology Edited by Cesar G. Fraga ISBN: 978-0-470-28721-7
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Cancer of the Thoracic Cavity: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of cancer of the lung and mediastinum. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on cancer of the thoracic cavity drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the molecular biology of lung cancer, non-small cell lung cancer, small cell and neuroendocrine tumors of the lung, and neoplasms of the mediastinum. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy applies to cancer of the thoracic cavity. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development. In one comprehensive volume, the editors, Dr. Rongshi Li and Dr. Jeffrey Stafford, present timely and important case studies of marketed kinase drugs and several of the most advanced kinase inhibitors in clinical trials. Kinase Inhibitor Drugs includes: Case studies from leading investigators and experts in the field that provide firsthand accounts of kinase inhibitor discovery Current thinking on kinase structure, biochemistry, and signal transduction pathways Information on state-of-the-art technologies and tools such as structure-based and fragment-based drug discovery A lineup of clinical-phase growth factor receptor inhibitors Inhibitors of cell cycle kinases The discovery of allosteric inhibitors of MEK kinase Information on pharmacogenomics and its application to kinase inhibitor clinical development
Accurately identify complex geometrical distortions of cardiac anatomy using 3-D echocardiography and make more informed decisions regarding diagnosis and treatment. A highly visual, consistent, and practical format with online videos and more presents the authoritative, case-based, expert guidance you need to enhance your utilization and interpretation of this cutting-edge, dimensional diagnostic tool. - Master the application of techniques to specific clinical situations with detailed case studies and discussions of challenging issues. - See imaging findings as they appear in practice and discern subtle nuances with the aid of high-quality still images plus online videos. - Reference the information you need quickly thanks to easy-to-follow, templated chapters, with an abundance of images and figures that facilitate visual learning. - Take it with you anywhere! Access the full text, downloadable image library, videos, and more at www.expertconsult.com.
Proceedings of the 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering, Patras, Greece, 9-11 October 2009
Proceedings of the 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering, Patras, Greece, 9-11 October 2009
This volume of proceedings consists of the papers presented during the 9th International Workshop on Mathematical Methods in Scattering Theory and Biomedical Engineering, held in Patras, Greece, on 9ndash;11 October 2009. The book contains papers on scattering theory and biomedical engineering - two rapidly evolving fields which have a considerable impact on today's research. All the papers are state-of-the-art, have been carefully reviewed before publication and the authors are well-known in the scientific community. in addition, some papers focus more on applied mathematics, which provides a solid ground for development and innovative research in scattering and biomedical engineering.
Comprising twenty-six chapters authored by fifty-seven esteemed academics, this book facilitates readers in comprehending the key findings, questions, and future research areas of individual differences research in organizational contexts.
This textbook provides practical tips on the conduct of aortic surgery, from the aortic valve to the iliac arteries. It is organized as a series of Plates, each with a key central illustration, followed by bullet items of accompanying explanatory text. The accompanying text concentrates on specific, critical “do’s and don’ts” that promote and enhance patient safety. Chapters include dozens of color illustrations by one of the nation’s premier medical illustrators, along with selected classic “pen and ink” line drawings. Each central illustration is accompanied by additional secondary figures interspersed at intervals within the accompanying text. Each “practical tip” has an accompanying short (15-30 second) video demonstrating vividly the specific didactic point being made in each Plate. Chapters provide Q&A sections, to promote an interactive feel and experience. The textbook shares practical, potentially life-saving tips—gleaned from over three decades of experience in thousands of aortic operations—regarding virtually every standard operation that arises in aortic surgery. Practical Tips in Aortic Surgery will be an essential resource for surgeons and trainees at all levels of experience: residents and fellows, surgical physician assistants, surgical nurses and technicians, and medical students. The book directly targets two surgical specialties: Cardiac Surgery and Vascular Surgery
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Lymphomas and Leukemias: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a complete and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of leukemias and lymphomas. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on leukemias and lymphomas drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of adult lymphomas and leukemias, including the molecular biology of lymphomas and acute and chronic leukemias; Hodgkin’s lymphoma; non-Hodgkin’s lymphoma; cutaneous lymphomas; management of acute and chronic leukemias, future directions and new treatments; myelodysplastic syndromes; plasma cell neoplasms; and more. Includes comprehensive information on leukemias and lymphomas of childhood, including supportive, long-term, palliative, and hospice care. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy apply to leukemias and lymphomas. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
Could Lincoln have lived? After John Wilkes Booth fired a low-velocity .44 caliber bullet into the back of the president's skull, Lincoln did not perish immediately. Attending doctors cleaned and probed the wound, and actually improved his breathing for a time. Today medical trauma teams help similar victims survive-including Gabby Giffords, whose injury was strikingly like Lincoln's. In Diagnosing Giants, Dr. Philip A. Mackowiak examines the historical record in detail, reconstructing Lincoln's last hours moment by moment to calculate the odds. That leads him to more questions: What if he had lived? What sort of neurological function would he have had? What kind of a Constitutional crisis would have ensued? Dr. Mackowiak, a professor at the University of Maryland School of Medicine, offers a gripping and authoritative account of thirteen patients who took center stage in world history. The result is a new understanding of how the past unfolded, as well as a sweeping survey of the history of medicine. What was the ailment that drove Caligula mad? Why did Stonewall Jackson die after having an arm amputated, when so many other Civil War soldiers survived such operations? As with Lincoln, the author explores the full contest of his subjects' lives and the impact of each case on the course of history, from Tutankhamen, Buddha, and John Paul Jones to Darwin, Lenin, and Eleanor Roosevelt. When an author illuminates the past with state-of-the-art scientific knowledge, readers pay attention. Candice Millard's Destiny of the Republic, about the medical malpractice that killed President James A. Garfield, was a New York Times bestseller. And Dr. Mackowiak's previous book, Post-Mortem: Solving History's Greatest Medical Mysteries, won the attention of periodicals as diverse as the Wall Street Journal and New England Journal of Medicine, which pleaded for a sequel. With Diagnosing Giants, he has written one with impeccable expertise and panache.
This report focuses on the risks of climate change to development in Sub-Saharan Africa, South East Asia and South Asia. Building on the 2012 report, Turn Down the Heat: Why a 4°C Warmer World Must be Avoided, this new scientific analysis examines the likely impacts of present day, 2°C and 4°C warming on agricultural production, water resources, and coastal vulnerability. It finds many significant climate and development impacts are already being felt in some regions, and that as warming increases from present day (0.8°C) to 2°C and 4°C, multiple threats of increasing extreme heat waves, sea-level rise, more severe storms, droughts and floods are expected to have further severe negative implications for the poorest and most vulnerable. The report finds that agricultural yields will be affected across the three regions, with repercussions for food security, economic growth, and poverty reduction. In addition, urban areas have been identified as new clusters of vulnerability with urban dwellers, particularly the urban poor, facing significant vulnerability to climate change. In Sub-Saharan Africa, under 3°C global warming, savannas are projected to decrease from their current levels to approximately one-seventh of total land area and threaten pastoral livelihoods. Under 4°C warming, total hyper-arid and arid areas are projected to expand by 10 percent. In South East Asia, under 2°C warming, heat extremes that are virtually absent today would cover nearly 60-70 percent of total land area in northern-hemisphere summer, adversely impacting ecosystems. Under 4°C warming, rural populations would face mounting pressures from sea-level rise, increased tropical cyclone intensity, storm surges, saltwater intrusions, and loss of marine ecosystem services. In South Asia, the potential sudden onset of disturbances to the monsoon system and rising peak temperatures would put water and food resources at severe risk. Well before 2°C warming occurs, substantial reductions in the frequency of low snow years is projected to cause substantial reductions in dry season flow, threatening agriculture. Many of the worst climate impacts could still be avoided by holding warming below 2°C, but the window for action is closing rapidly. Urgent action is also needed to build resilience to a rapidly warming world that will pose significant risks to agriculture, water resources, coastal infrastructure, and human health.
Be ready to prescribe and administer drugs safely and effectively, with the fully updated Pharmacotherapeutics for Advanced Practice, 5th Edition. Anchored in pharmacology and the principles of therapeutics, and written by experts in the field, this is your road map to effective drug therapies. Learn to correctly identify a disorder, review the drugs used to treat it, and select the optimal therapy. With expert direction on more than 50 common disorders, this is the ideal resource for advanced practice clinicians and students learning pharmacotherapeutics, and a go-to reference for experienced clinicians.
Now in a revised and expanded 7th Edition, Kaplan's Cardiac Anesthesia helps you optimize perioperative outcomes for patients undergoing both cardiac and noncardiac surgery. Dr. Joel L. Kaplan, along with associate editors, Drs. John G. T. Augoustides, David L. Reich, and Gerard R. Manecke, guide you through today's clinical challenges, including the newest approaches to perioperative assessment and management, state-of-the art diagnostic techniques, and cardiovascular and coronary physiology. - Complete coverage of echocardiography and current monitoring techniques. - Guidance from today's leaders in cardiac anesthesia, helping you avoid complications and ensure maximum patient safety. - More than 800 full-color illustrations. - A new section on anesthetic management of the cardiac patient undergoing noncardiac surgery. - New availability as an eBook download for use the in OR. - Online-only features, including quarterly updates, an ECG atlas...an increased number of videos, including 2-D and 3-D TEE techniques in real time...and an Annual Year End Highlight from the Journal of Cardiovascular Anesthesia that's posted each February. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
The world's leading reference in hematopathology returns with this completely updated second edition. Authored by international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant -- with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. Comprehensive in scope, it's a must-have resource for both residents and practicing pathologists alike. - Authored by the chief architects of the WHO classification in neoplasms of hematopoietic and lymphoid tissue. - Covers the newest diagnostic techniques, including molecular, immunohistochemical, and genetic studies. - Confirm or challenge your diagnostic interpretations by comparing specimens to over 1,000 high-quality color images. - Boasts detailed, practical advice from world leaders in hematopathology. - Places an emphasis on pathologic diagnoses, including molecular and genetic testing. - Updated with the most current WHO classifications of hematologic disease, including lymphoma and leukemia and peripheral T-cell lymphomas. - Covers hot topics in hematopathology, such as the latest genetic insights into lymphoma and leukemia; the new nomenclature for myelodysplastic syndromes; new developments on the subject of Grey zone lymphoma; and much more. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. There's also a downloadable image bank, and Virtual Microscope Slides are featured in several chapters.
Knowledge itself is soon obsolete; It is a blunt instrument. Only by understanding can problems be solved and progress achieved. Reliability in performance of electronic equipment, in the face of demands for continuing miniaturisation and the anticipated abolition of lead containing solders, represents a major engineering challenge. The involvement of numerous disciplines; such as electrical, electronic, mechanical, manufacturing, and materials engineering together with physicists and computer specialists, adds to the complexity of the situation. Nevertheless, with electronics being the World's largest industrial sector, the potential rewards to the winners are substantial. This book aims to provide the ingredients for understanding, together with knowledge of reliability in interconnection technology and of the implementation of lead free solders. It is strongly contended that such a combination forms the necessary basis for greater structural integrity and enhanced performance The text is essentially in three parts: The intentions of the Part I component {The Materials Perspective, Chapters 1 6) are to present a snapshot of the current, but rapidly changing, global scene and to establish a firm understanding of the fundamentals surrounding interconnection performance. With potential readers possessing a broad spectrum of knowledge and expertise, this is essential. It could be argued that the reason for the limited progress made in this field to date has been due to the difficulties encountered in communicating effectively across the discipline boundaries.
The Sounds of the Diseased Heart presents the comprehensive study on auscultation and phonocardiography. It discusses the description of the sounds of the normal heart. It addresses the dynamic interpretation of cardiovascular murmurs. Some of the topics covered in the book are the abnormal first heart sound; hypertrophy or dilatation of the left ventricular wall; dilatation of the pulmonary artery; moderate pulmonary stenosis; atrial septal defect; changes in the duration of ejection; ventricular type of triple rhythm; and differential diagnosis between the pulmonary component, the opening snap, and the third sound. The general interpretation of triple and quadruple rhythms is fully covered. The dynamic correlations of cardiovascular murmurs are discussed in detail. The text describes in depth the semilunar valve stenosis. The mitral valve and tricuspid valve defects are presented completely. A chapter is devoted to the esophageal phonocardiography. The book can provide useful information to cardiologists, doctors, students, and researchers.
This is the 3rd volume of a "Light Scattering Reviews" series devoted to current knowledge of light scattering problems and both experimental and theoretical research techniques related to their solution. This volume covers applications in remote sensing, inverse problems and geophysics, with a particular focus on terrestrial clouds. The influence of clouds on climate is poorly understood. The theoretical aspects of this problem constitute the main emphasis of this work.
Essentials of Chemical Biology Discover a detailed knowledge of concepts and techniques that shape this unique multi-discipline Chemical Biology is devoted to understanding the way that Biology works at the molecular level. This is a problem-driven multi-discipline, incorporating as it does Organic, Physical, Inorganic, and Analytical Chemistry alongside newer emerging molecular disciplines. In recent years, Chemical Biology has emerged as a vibrant and growing multi-discipline distinct from Biochemistry that is focused on the quantitative analyses of the structures and functions of biological macromolecules and macromolecular lipid assemblies, at first in isolation, then in vitro and in vivo. The second edition of the Essentials of Chemical Biology begins with a thorough introduction to the structure of biological macromolecules and macromolecular lipid assemblies, before moving on to the principles of chemical and biological synthesis, followed by descriptions of a comprehensive variety of research techniques and experimental methods. In addition, the second edition now includes new sections on the behaviour of biological macromolecules and macromolecular lipid assemblies in cells in vitro and in organisms in vivo. Given this, the second edition of the Essentials of Chemical Biology promises to cement itself as the leading introduction to Chemical Biology, incorporating descriptions of cutting-edge research wherever appropriate. Hence, readers of the second edition of the Essentials of Chemical Biology will find: a general expansion in understanding of basic molecular mechanisms in Biology moving towards cellular and organismal mechanisms entirely new chapters covering miniaturization and array technologies, Chemical Cell Biology, and the interface between Chemical Biology and Nanotechnology updates to chapters reflecting recent research developments an increased engagement with medical applications Essentials of Chemical Biology is ideal for advanced undergraduates or (post) graduate students in Chemical Biology and adjacent fields.
Interviewing has become the window on the world of experience for both researchers and professionals. But as familiar as interviewing is now, its seemingly straightforward methodology raises more questions than ever. What is the interviewer's image of those who are being interviewed? Who is the interviewer in the eyes of the respondent? From where do interviewers obtain questions and respondents get the answers that they communicate in interviews? How do the institutional auspices of interviewing shape interview data? Drawing upon leading experts from a wide range of disciplines to address these and related questions, The Handbook of Interviewing offers a comprehensive examination of the interview at the cutting edge of information technology in the context of a challenging postmodern environment. Encyclopedic in its breadth, the Handbook provides extensive discussions of the conceptual and methodological issues surrounding interview practice in relation to forms of interviewing, new technology, diverse data gathering and analytic strategies, and the various ways interviewing relates to distinctive respondents. The Handbook is also a story that spins a particular tale that moves from the commonly recognized individual interview as an instrument for gathering data to reflections on the interview as an integral part of the information we gather about individuals and society.
This 3rd edition presents cutting-edge standards of pacing and defibrillation to keep you at the forefront of this rapidly expanding field. You'll find coverage of all the new devices and management strategies you need to solve a full range of clinical problems using today's best approaches. Written by world authorities on pacing and devices for cardiac care, this new full-color 3rd edition is the more practical than ever! Addresses the management of patients with a broad range of conditions, including sinus node disease, carotid sinus hypersensitivity, tachyarrhythmias, heart failure, and more. Details cardiac pacing in pediatric patients. Illustrates vital concepts and techniques with over 745 x-rays and figures. Explains how to approach pacemaker generator changes. Reviews fundamental concepts such as how to pace the heart and how leads, power sources, programmers, and electronic circuitry work. Contains a new chapter on resynchronization trials. Offers technical information on both new and old devices to help you make the correct choice for every patient. Provides new material on implantation, with key updates to all aspects of this challenging clinical area.
Origami structures have the ability to be easily fabricated from planar forms, enable the deployment of large structures from small volumes, and are potentially reconfigurable. These characteristics have led to an increased interest in theoretical and computational origami among engineers from across the world. In this book, the principles of origami, active materials, and solid mechanics are combined to present a full theory for origami structures. The focus is on origami structures morphed via active material actuation and formed from sheets of finite thickness. The detailed theoretical derivations and examples make this an ideal book for engineers and advanced students who aim to use origami principles to develop new applications in their field.
- Content adapted for the current South Asian nursing setup - Current data and statistics pertaining to the South Asian region assimilated - Newest concepts and literature added to reflect the regional perspective - Regional pictures added to provide regional look and feel
Offering a thorough, accessible overview of the basic science and clinical data regarding the virus that causes COVID-19, Molecular Biology of SARS-CoV-2 is an excellent resource for researchers, clinical scientists, physicians, and students. This volume offers in-depth, extended content that originated with Drs. Roberto Patarca’s and William A. Haseltine’s chapter in The COVID-19 Textbook, edited by Dr. Haseltine and Dr. Patarca. The greatly expanded material in this text provides a much-needed primer in this complex area.
To address the exponential growth in the fields of pediatric hematology and oncology, this classic reference has been separated into two distinct volumes. With this volume, devoted strictly to pediatric hematology, and another to pediatric oncology, you’ll keep you on the cutting-edge of these two specialties. The completely revised 7th edition of Nathan and Oski’s Hematology of Infancy and Childhood is now in full color, and provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with hematologic disorders. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of blood diseases that you encounter in everyday practice. Written by the leading names in pediatric hematology, this resource is an essential tool for anyone involved in caring for children with hematologic disorders. Balances summaries of relevant pathophysiology with clear, practical clinical guidance to help you thoroughly understand the underlying science of diseases. Offers comprehensive coverage of all hematologic disorders, including newly recognized ones, along with the latest breakthroughs in diagnosis and management. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines at a glance. Presents an all-new full-color design that includes clear illustrative examples of relevant science and clinical problems for quick access to the answers you need.
The 2nd edition of Catheter Ablation of Cardiac Arrhythmias, written by Shoei K. Stephen Huang, MD and Mark A. Wood, MD, provides you with the most comprehensive and detailed coverage of the latest ablation techniques, from direct-current to radiofrequency to cryoenergy. It offers the latest information on anatomy, diagnostic criteria, differential diagnosis, mapping, and the use of echocardiography to assist in accurate diagnosis and management of cardiac arrhythmias. Authored by two of the world’s leading experts in catheter ablation, this text includes a unique section on troubleshooting difficult cases, and its use of tables, full-color illustrations, and high-quality figures is unmatched among publications in the field. Get the most comprehensive and detailed coverage of arrhythmias and ablation technologies, highlighted by a systematic approach to troubleshooting specific problems encountered in the laboratory – complete with solutions. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly chapter format. Master each approach with exceptional visual guidance from tables, illustrations, high-quality figures. Review basic concepts and build clinical knowledge using extensive tables that present specific ''hard-to-remember'' numerical information used in diagnosis, and mapping to summarize key information in each chapter. Improve accuracy with assistance from advanced catheter mapping and navigation systems and use of intracardiac echocardiography to assist accurate diagnosis and ablation. Keep pace with an updated and expanded section on atrial fibrillation. Stay current on timely topics like contemporary cardiac mapping and imaging techniques, atrial tachycardia and flutter, atrial fibrillation, atrioventricular nodal reentrant tachycardia, tachycardias related to accessory atrioventricular connections, and ventricular tachycardia, transseptal catheterization, ablation for pediatric patients, and patient safety and complications.
In this book, readers embark on a journey through the intricate web of climate change, its causes, and the far-reaching consequences it has on our world. From the greenhouse gas effect to shifting weather patterns, this book meticulously dissects the science behind climate change. It explores its impact on vital sectors like agriculture, food production, horticulture, and even the intricate relationships between microorganisms and our changing climate. Offering practical insights, the book unveils adaptation and mitigation strategies essential for safeguarding our planet. This is a comprehensive book that equips readers with the knowledge needed to understand and address one of the most pressing global challenges of our time.
Der Autor George Olah, der 1995 den Nobelpreis erhielt, stellt in seinem Buch die Anwendung von Onium-Ionen als elektrophile Reagenzien und Katalysatoren dar und erläutert diese für die chemische Synthese bedeutsamen Verbindungen. (8/98)
Now thoroughly updated to include new advances in the field,and with regular content updates to the eBook, Principles and Practice of Pediatric Oncology, 7th Edition remains the gold standard text for the care and research of children with cancer. This authoritative reference is the single most comprehensive resource on the biology and genetics of childhood cancer and the diagnosis, multimodal treatment, and long-term management of young patients with cancer. Also addressed are a broad array of topics on the supportive and psychosocial aspects of care of children and families. Covering virtually every aspect of the breadth and depth of childhood cancer, this 7th Edition provides expert guidance on state-of-the-art, multidisciplinary care for children and families. Stay up to date with the most recent advances in the field with the contributions by new and returning contributors, including the perspective from patients and parents in the chapter titled “The Other Side of the Bed.” Reference your eBook version for key updates in the field during the life of the edition! Chapters included on palliative care and education. Supportive care is covered broadly and specifically – in contexts such as emergencies, infectious disease, and nutrition. The most updated and authoritative information is provided by the leading experts in the field. Gain a thorough understanding of every aspect of pediatric oncology, with comprehensive information regarding basic science, diagnostic tools, principles of treatment, and clinical trials, as well as highly detailed, definitive coverage of each pediatric malignancy. Collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families. Understand the cooperative nature of pediatric oncology as a model for cancer research with information from cooperative clinical trial groups and consortia.
Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns
A comprehensive overview of clinically important infections of the urinary tract Urinary tract infections (UTIs) continue to rank among the most common infectious diseases of humans, despite remarkable progress in the ability to detect and treat them. Recurrent UTIs are a continuing problem and represent a clear threat as antibiotic-resistant organisms and infection-prone populations grow. Urinary Tract Infections: Molecular Pathogenesis and Clinical Management brings the scientific community up to date on the research related to these infections that has occurred in the nearly two decades since the first edition. The editors have assembled a team of leading experts to cover critical topics in these main areas: clinical aspects of urinary tract infections, including anatomy, diagnosis, and management, featuring chapters on the vaginal microbiome as well as asymptomatic bacteriuria, prostatitis, and urosepsis the origins and virulence mechanisms of the bacteria responsible for most UTIs, including uropathogenic Escherichia coli, Proteus mirabilis, and Klebsiella pneumoniae the host immune response to UTIs, the rise of antibiotic-resistant strains, and the future of therapeutics This essential reference serves as both a resource and a stimulus for future research endeavors for anyone with an interest in understanding these important infections, from the classroom to the laboratory and the clinic.
Featuring 900 full-color illustrations, this book is a concise and practical atlas of the surgical pathology and cytology of the head and neck. It covers the most common head and neck lesions and tumors the general pathologist sees in daily practice and will aid pathology residents and practitioners in quickly narrowing down a histologic differential diagnosis. Integral to the images provided are illustrated criteria for achieving a diagnosis—essentially what to look for when reviewing pathology slides. Differential diagnoses are shown, as are pitfalls in the diagnosis. A companion Website will offer the fully searchable text and an image bank.
Over 5,000 illustrations of the latest imaging and research findings essential for effective diagnosis of retinal disorders populate this atlas. A unique page layout consisting of optimally positioned panoramic images, magnified photos, and histopathological specimens illustrate key manifestations, giving you the best visual display of each disease. In addition, composite images using different retinal imaging modalities, including the latest in optical coherence tomography (OCT), fluorescein angiography, indocyanine green (ICG), and fundus autofluorescence display how a disease appears in each imaging modality, allowing you to compare imaging methods and gain a better understanding of each disorder.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Cancer of the Skin: From Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology/hematology practitioners, fellows, and others who need an in-depth understanding of skin cancers. The print reference gives you the solid, dependable guidance you have come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors. Delivers focused, comprehensive information on cancer of the skin drawn from the world’s leading cancer textbook, DeVita, Hellman, and Rosenberg’s Cancer: Principles & Practice of Oncology. Covers the full range of skin cancers, including nonmelanoma skin cancer, actinic keratosis, basal cell carcinoma, squamous cell carcinoma, angiosarcoma, microcystic adnexal carcinoma, and more; as well as cutaneous melanoma, including molecular biology; and genetic testing in skin cancer. Discusses in detail the growing importance of prevention and screening, giving you the understanding you need to improve your patients’ chances for a healthier, cancer-free life. Explains how the latest developments in biologic therapy applies to skin cancer. Provides exhaustive coverage of combined modality cancer treatment, helping you determine when and how to integrate modalities in patient treatment. Ensures that you are fully up to date thanks to easy, mobile access to quarterly updates.
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