A masterful and thorough revision of the only single-source, authoritative reference on cutaneous lymphoproliferative disease. Classic reference for unsurpassed coverage of lymphocytic infiltrates of the human skin Covers a broad spectrum of topics ranging from the role of the immune system in the pathogenesis of cutaneous lymphocytic infiltrates to one describing the immunohistochemica nd molecular aspects of lymphoid neoplasia. Each chapter contains an extensive array of ‘clinical vignettes’ clearly showing the application of principles and treatment techniques discussed in the chapter Presents a succinct and logical approach to the diagnosis of most cutaneous lymphocytic infiltrates and discusses the interplay between the immune system in the propagation of lymphocytic infiltrates focusing on the role of iatrogenic and endogenous immune dysregulation. The molecular and cytogenetic basis of lymphoid neoplasia is considered in great detail. Contains hundreds of full-color, high-quality clinical and histologic photographs, with over 200 new images in the new edition
This book addresses the fields of biodegradation, environmental degradation, and photochemical degradation. The purpose of the book is to establish guidelines for terminology, nomenclature, characterization techniques and methodology, mechanisms of degradation, standard reference materials, and issues and needs. This is the first scientific book of this nature based on the findings of the world's leading scientists (academic, industrial, and federal) in this field. Hard data is presented and soft data is identified under issues and needs. New areas covered are such topics as: biodegradation with in vivo applications, environmental degradation, including anaerobic, aerobic, characterization techniques and methodology, photochemical degradation, and secondary issues associated with degradation. This publication contains information vital to environmental scientists and engineers, biomaterials scientists, pharmaceutical technologists, and chemists.
A comprehensive and interdisciplinary guide to systems engineering Systems Engineering: Principles and Practice, 3rd Edition is the leading interdisciplinary reference for systems engineers. The up-to-date third edition provides readers with discussions of model-based systems engineering, requirements analysis, engineering design, and software design. Freshly updated governmental and commercial standards, architectures, and processes are covered in-depth. The book includes newly updated topics on: Risk Prototyping Modeling and simulation Software/computer systems engineering Examples and exercises appear throughout the text, allowing the reader to gauge their level of retention and learning. Systems Engineering: Principles and Practice was and remains the standard textbook used worldwide for the study of traditional systems engineering. The material is organized in a manner that allows for quick absorption of industry best practices and methods. Systems Engineering Principles and Practice continues to be a national standard textbook for the study of traditional systems engineering for advanced undergraduate and graduate students. It addresses the need for an introductory overview, first-text for the development and acquisition of complex technical systems. The material is organized in a way that teaches the reader how to think like a systems engineer and carry out best practices in the field.
Alkoxo and Aryloxo Derivatives of Metals gives a comprehensive account of the chemistry of metal alkoxides and metal aryloxides, including their industrial applications such as microelectronics, ceramics, nonlinear optical materials, high-temperature superconductors, specialized glasses, and other advanced novel materials. It is an invaluable reference source book. The book is an updated edition of Metal Alkoxides, published by Academic Press in 1978, with additional coverage of metal aryloxides. It reflects the enormous growth in interest in this field in recent years. Alkoxo and aryloxo derivatives are organic compounds with metals for useful industrial purposes. Alkoxo and Aryloxo Derivatives of Metals will appeal to a wide-ranging audience, including university researchers and chemistry graduate students in industrial laboratories concerned with microelectronics, ceramics, glasses and other advanced novel materials; any laboratories doing research on nonlinear optical materials, high-temperature superconductors, ceramic materials, and specialized glasses. It can also serve as a supplementary text for final year courses in advanced inorganic chemistry, e.g., metallo-organic chemistry.
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
In a single, convenient volume, Pediatric Endocrinology offers complete coverage of all aspects of basic science and clinical practice, ideal for both pediatricians and endocrinologists. Pediatric endocrinology expert Dr. Mark Sperling teams up with world-renowned authors to bring you up to date with the latest key developments in every area of the field, providing invaluable guidance on how your clinical decision making will be affected by today’s technological and scientific advances. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Determine the best possible course for every patient with easy-to-follow algorithms in every clinical chapter. Stay up to date with today’s hottest topics, including neonatal diabetes mellitus, Type II childhood diabetes, molecular endocrinology, and genetics. Explore the impact of today’s advances and challenges, including explosive growth in molecular biology, sophisticated imaging techniques, and an increase in both pediatric diabetes and obesity. Quickly access the information you need with a new, streamlined organization (Concepts, Endocrine Disorders of the Newborn, Endocrine Disorders of Childhood and Adolescence, and Laboratory Tests and Imaging).
Natural disasters are increasingly affecting the world, taking lives unexpectedly and leaving many others injured and homeless. Moreover, disasters disrupt local, national and even global economies, instantly changing the direction of development. In the first half of 2011 alone, 108 natural disasters occurred, killing over 23 thousand people, affecting nearly 44 million others and causing more than 253 billion US dollars of economic damages (CRED 2011,1). Large urban settlements have become increasingly vulnerable to the impacts of natural disasters. The concentration of substandard infrastructure and housing, material assets, and inherent socio-economic inequalities increase vulnerability to disasters in large urban areas, especially in developing countries. The size, number, functions, and geographical distribution of large- and megacities create a special concern for disaster risk. Good urban management practices can be a powerful catalyst for reducing losses from natural disasters, while simultaneously helping to develop a sustainable environment. Yet, the existing situation indicates that sustainable planning and risk management measures are not taken into consideration or may not be put into practice for a variety of financial, political, and social reasons. This book argues that, on one hand, socio-economic disparities resulting from unsustainable urban development can increase vulnerability to natural hazards, and on the other hand, when paired with natural hazards this increased vulnerability can negatively affect urban areas, resulting in further inequality. This book will showcase this argument with theoretical reviews and quantitative analyses on the interplay between sustainable development and disaster vulnerability as well as an in-depth case study of the role of urban planning and risk management practices in creating the socio-economic and spatial vulnerabilities and predicted earthquake risk in the megacity of Istanbul.
Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and health. The final section focuses on CK2 and cancer, looking at the impacts of the kinase on neoplastic development and its rapidly developing role as a therapeutic agent. With contributions from the world’s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme. This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Editor Lorenzo A. Pinna is Professor in the Department of Biomedical Sciences at the University of Padua, Padua, Italy. Also Published in the Wiley-IUBMB Series on Biochemistry and Molecular Biology: Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology Edited by Cesar G. Fraga ISBN: 978-0-470-28721-7
Gastrointestinal mucosal biopsies are an active part of the pathologist’s day and have increased in the past few years as endoscopic screening has become more commonplace. This new full-color Second Edition of Biopsy Interpretation of the Gastrointestinal Tract Mucosa has been expanded into two concise, comprehensive volumes to offer more complete coverage of both non-neoplastic and neoplastic entities. Like the other books in the Biopsy Interpretation Series, these volumes are practical references for pathologists to use when making diagnostic decisions based on biopsy specimens. Volume 2 will focus on neoplastic biopsies and will publish in March 2012.
This book summarizes the best available evidence concerning the most common clinical questions that anesthesiologists face every day, so you will have an informed basis for making effective patient management decisions. This new edition covers 24 new topics and explores a full range of important issues in perioperative management-discussing the clinical options, examining the relevant research, and presenting expert recommendations. It features the latest information on clinical situations and reviews all clinical options based on the most recent clinical trials, providing a valuable framework for translating evidence into practice.
By 1940, immunological mechanisms had been proved to have fundamental influ ences on a great number and variety of skin reactions, and skin diseases had brought to light a great number of fundamental immunological mechanisms that were basic to a wide range of different diseases, dermatological and nondermato logical. The preeminence of dermatological research in the advancement of immu nological knowledge should not astonish anyone. For the skin is not only the most easily accessible tissue for producing and studying immunological reactions, it is also the great organ of protection that meets the first onslaughts of inimical environmental forces and agents-potential enemies, both living and dead. And protection is in essence what immunology is all about. To get an idea of the long-established role that testing the skin and the study of its many reactions has played in advancing general immunology, one need recall only smallpox vaccination; tuberculin testing; testing with fungal extracts; skin testing in hay fever, asthma, and serum sickness; skin tests with toxins and toxoids; the patch test; the passive transfer of skin-adhering antibodies (reagins); skin sensitization by simple chemicals; and similar dermatological procedures that have exerted their influence on medical and scientific disciplines far beyond dermatology.
Many neurologic disorders can appear in quick and severe forms that require immediate medical attention. This issue of Neurologic Clinics features 14 articles on conditions that commonly present acutely, such as epilepsy, headache, visual loss, nervous system infections, ischemic stroke, head and spinal cord injury, and intracranial hemorrhage.
The twelfth edition of this classic reference work includes: - More than 2,000 new entries - A total of more than 9,000 entries - New features and enhancement of the familiar old features - Mapping information on more than 4,000 genes of known function - Information on specific point mutations responsible for more than 700 genetic disorders or neoplasms Mendelian Inheritance in Man (MIM) is a genetic knowledgebase that serves clinical medicine and biomedical research, including the Human Genome Project. It aims to be comprehensive (not only complete, but also collated, integrated, and interpreted), authoritative (not only accurate but also sound in its interpretations and judgements), and timely (not only up-to-date but also historically dimensioned). From a review of the eleventh edition, Reproductive Toxicology: "Even the convenience of computer-based forms of MIM cannot eliminate the need for MIM in book form. The preface provides a wonderful synopsis of human genetics. The information contained in this text serves as a concise review for those with a genetics background." From a review of the tenth edition, New England Journal of Medicine: " Victor McKusick] has been for all these years the shepherd of the development of the field of clinical genetics]. Perhaps his most important pragmatic achievement has been the 10 editions of Mendelian Inheritance in Man, which rapidly became and has remained the principal source of information on inherited diseases for all clinical geneticists. "In addition to the erudite entries in the books, the references given with each description represent a magnificent bibliography of clinical genetics. With McKusick's leadership and continued interest in gene mapping, the book also rep-resents an important compen-dium of the location of genes on specific chromosomes. "The book is a magnificent security blanket for the clinical geneticist and should be in the libraries not only of these specialists, but also of all others who see patients with diseases that have genetic components.
A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. - An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. - Has a practical, accessible approach with free use of algorithms, list tables. - Aimed at the whole transplant team - this is an interdisciplinary field. - International contributor team with editors in the UK and USA. - Illustrated in colour throughout.
Few lives provide as much history or drama as those of monarchs. Filmmakers from the silent era to onward have displayed a deep fascination with the lives of royalty and with queens in particular. Still, the question remains: what do these films really tell us about the women beneath the crowns? Drawing on films from the 1930s to those of today, Royal Portraits in Hollywood: Filming the Lives of Queens investigates the ways in which these films reproduce history and represent women. Though hardly progressive in nature, many early films offered an acceptable, nonthreatening way to present strong female characters in an economic and social landscape run almost exclusively by men. Authors Elizabeth Ford and Deborah Mitchell track the evolution of queens on film, noting how depictions of prominent women have changed over the past several decades and calling attention to the ways in which films both reflect and dictate the social norms of their eras. By comparing historical records of monarchs such as Queen Christina of Sweden, Catherine the Great, Cleopatra, and Elizabeth I with their onscreen personas, and examining the biographical details of the actresses who portrayed these women, Ford and Mitchell present a fascinating inquiry into issues of historical accuracy and gender politics in film.
Nutrition: Science and Applications, 3rd Canadian Edition, provides students with a strong foundational knowledge of human nutrition, covering all essential nutrients, their functions in the body, and their sources and dietary components. Presenting an innovative critical-thinking approach to the subject, this leading textbook goes beyond the basics to explore underlying nutrition processes while discussing the latest research, debates, and controversies related to nutrition and health. The text offers an accessible, visually-rich presentation of topics designed to be highly relevant and relatable to Canadian readers. The ideal text for college-level nutrition courses, this new edition features extensively revised and updated content throughout — aligning with the latest nutrition research, recommendations, guidelines, and Canadian government regulations. The authors real-world approach enables students to apply concepts of nutrition science in their own lives as consumers, and in their future careers as scientists and health professionals. Balanced coverage of fundamental nutrition topics integrates with comprehensive discussion of nutrient metabolism, health and disease relationships, dietary patterns, Canadian and global nutrition issues, and much more.
Modern electronics testing has a legacy of more than 40 years. The introduction of new technologies, especially nanometer technologies with 90nm or smaller geometry, has allowed the semiconductor industry to keep pace with the increased performance-capacity demands from consumers. As a result, semiconductor test costs have been growing steadily and typically amount to 40% of today's overall product cost. This book is a comprehensive guide to new VLSI Testing and Design-for-Testability techniques that will allow students, researchers, DFT practitioners, and VLSI designers to master quickly System-on-Chip Test architectures, for test debug and diagnosis of digital, memory, and analog/mixed-signal designs. - Emphasizes VLSI Test principles and Design for Testability architectures, with numerous illustrations/examples. - Most up-to-date coverage available, including Fault Tolerance, Low-Power Testing, Defect and Error Tolerance, Network-on-Chip (NOC) Testing, Software-Based Self-Testing, FPGA Testing, MEMS Testing, and System-In-Package (SIP) Testing, which are not yet available in any testing book. - Covers the entire spectrum of VLSI testing and DFT architectures, from digital and analog, to memory circuits, and fault diagnosis and self-repair from digital to memory circuits. - Discusses future nanotechnology test trends and challenges facing the nanometer design era; promising nanotechnology test techniques, including Quantum-Dots, Cellular Automata, Carbon-Nanotubes, and Hybrid Semiconductor/Nanowire/Molecular Computing. - Practical problems at the end of each chapter for students.
Art Therapy with Students at Risk: Fostering Resilience and Growth Through Self-Expression reflects the current research, legislation, and trends that impact the theory and practice of art therapy with diverse at-risk student populations. The book is divided into eight chapters and it includes twelve therapeutic techniques. The 12 therapeutic techniques are written in a lesson plan format which provide opportunities for children to express their thoughts and feelings coupled with confirmation that their art is important to them and to others. Chapter 1, “Adolescence,” examines the developmental period between childhood and adulthood. Chapter 2, “Alternative Schools,” describes the development of alternative schools in the United States through legislative reform, education reform, and civil rights. Chapter 3, “Alternative Education,” explores the catalyst for policymakers to make quality education a civil rights issue. Chapter 4, “Emotions and Learning,” investigates the relationship between emotions and learning and the impact of this relationship on academic achievement. Chapter 5, “Multicultural and Diversity Competence,” focuses on the changing demographics in the United States which have significant implications for the art therapy profession. Chapter 6, “From Risk to Resilience,” highlights the paradigm shift in resilience research away from the deficit, pathology-focused model of development, referred to as the Damage Model to the Challenge Model. Chapter 7, “Art Psychotherapy,” provides insight into the unique criteria that distinguishes it from other types of psychotherapy. Chapter 8, “Art Therapy with Students at Risk,” presents a foundational framework for developing and implementing an art therapy program within a traditional or nontraditional learning environment. This book is designed for art therapy students, professional art therapists, educators, administrators, and practitioners in the allied professions of counseling, social work, psychology, prevention, and human services.
Responding to the growing recognition of Obstructive Sleep Apnea (OSA) as a major medical condition and the emergence of exciting new therapies, this 2 volume source examines clinical features, characteristics, comorbidities, and impact of OSA on patient biological systems. Not to mention, diagnosis and treatment methods that include first-line and
A systems-level approach to reducing liability through process improvement Forensic Systems Analysis: Evaluating Operations by Discovery presents a systematic framework for uncovering and resolving problematic process failures. Carefully building the causal relationship from process to product, the discussion lays out in significant detail the appropriate and tactical approaches necessary to the pursuit of litigation with respect to corporate operations. Systemic process failures are addressed by flipping process improvement models to study both improvement and failure, resulting in arguments and methodologies relevant to any product or service industry. Guidance on risk analysis of operations combines evaluation of process control, stability, capability, verification, validation, specification, product reliability, serial dependence, and more, providing a robust framework with which to target large-scale nonconforming products and services. Relevant to anyone involved in business, manufacturing, service, and control, this book: Covers process liability and operations management from both engineering and legal perspectives Offers analyses that present novel uses of traditional engineering methods concerning risk and product quality and reliability Takes a rigorous approach to system tactics and constraints related to product and service operations and identifies dysfunctional processes Offers both prescriptive and descriptive solutions to both the plaintiff and the defendant The global economy has created an environment in which huge production volume, complex data bases, and multiple dispersed suppliers greatly challenge industrial operations. This informative guide provides a practical blueprint for uncovering problematic process failures.
The discovery of new algorithms for dealing with polynomial equations, and their implementation on fast, inexpensive computers, has revolutionized algebraic geometry and led to exciting new applications in the field. This book details many uses of algebraic geometry and highlights recent applications of Grobner bases and resultants. This edition contains two new sections, a new chapter, updated references and many minor improvements throughout.
One of the best-selling titles in the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Gastrointestinal Tract Mucosa Volume 2 Neoplastic, Fourth Edition, by Drs. Elizabeth A. Montgomery and Lysandra Voltaggio, provides practical, highly illustrated information on mucosal biopsies from the esophagus, stomach, small intestine, large intestine, and anus. Well-organized and highly readable, this fully revised volume offers the information you need to successfully navigate both common and unusual issues that arise in the day-to-day interpretation of gastrointestinal biopsies. Volume Two focuses on neoplastic entities; also available is Volume One, your complete guide to non-neoplastic gastrointestinal lesions.
This book adds to the growing literature on dynamics of regional development in the global South by mapping the politics and processes contributing to the distinct developmental trajectory of Tamil Nadu, southern India. Using a novel interpretive framework and drawing upon fresh data and literature, it seeks to explain the social and economic development of the state in terms of populist mobilization against caste-based inequalities. Dominant policy narratives on inclusive growth assume a sequential logic whereby returns to growth are used to invest in socially inclusive policies. By focusing more on redistribution of access to opportunities in the modern economy, Tamil Nadu has sustained a relatively more inclusive and dynamic growth process. Democratization of economic opportunities has made such broad-based growth possible even as interventions in social sectors reinforce the former. The book thus also speaks to the nascent literature on the relationship between the logic of modernisation and status based inequalities in the global South.
By examining historical applications of the compounds found in plants, this five-volume series serves as a reference for quality assurance, research, product development, and regulatory guidance of the compounds found in plant-based medicines. This work supports the growing consumers' interest in herbal medicine for wellness and health. Plant-Based Therapeutics, Volume 1: Cannabis sativa, the first in the series, covers a unique plant species and provides the framework to integrate its evidence-based scientific discoveries with healthcare therapies. Cannabis has been used in religious ceremonies and medical purposes for thousands of years. Cannabidiol (CBD), the main non-psychoactive component of Cannabis, was isolated in the 1940s, and its structure was established in the 1960s. In 1964 tetrahydrocannabinol (THC), the psychoactive component, was isolated. Cannabis has more than 500 components, of which 104 cannabinoids have been identified. Two of them, THC and CBD, have been the primary components of scientific investigations. They were approved by the FDA for chemotherapy-induced nausea and vomiting in 1985; for appetite stimulation in wasting conditions, such as AIDS, in 1992, and in 2018 for treating two forms of pediatric epilepsy, Dravet syndrome and Lennox-Gastaut syndrome. Beyond the indications for which cannabinoids are FDA-approved, the evidence reveals that cannabinoid receptors are present throughout the body, embedded in cell membranes, and are believed to be more numerous than any other receptor system. When cannabinoid receptors are stimulated, a variety of physiologic processes ensue. Thus, other constituents of Cannabis are extremely promising either as individual compounds or their potential synergistic or entourage effects in the treatment of numerous medical conditions.
Lignans, by convention, are a group of natural products that are formed by linking two phenylpropanoid units (C C units) by oxidative coupling. Most importantly, in 6 3 a lignan, two (C C units) are bound through the central carbon of their side chains, 6 3 0 i. e. the 8 and 8 positions (1, 2). The occurrence of C C -dimers, linked at sites other 6 3 0 than the 8–8 positions, is also known and these compounds have been termed neolignans (3, 4). As these two groups of compounds have close structural as well as biosynthetic relationships, they are often associated together and incorporated under the general term “lignan” (5). The diverse structural categorization of true lignans and of a few neolignans is presented in Fig. 1. Through the years, several review articles or books covering different facets of lignans, including their ch- istry (6, 7), biogenesis (8), synthesis (9), and biological activities (10) have been published. Enduring research for the investigation of secondary metabolites of plants has evidenced some compounds that are biogenetically related to true lignans or neolignans but bear some features not discerned in conventional lignans. These compounds or groups of compounds have been termed as “non-conventional lignans”, and include coumarinolignans, ?avonolignans, and stilbenolignans. The non-conventional lignans, like the conventional ones, have two C C units linked 6 3 together but have additional structural features to place them also under the category of coumarins, ?avonoids, or stilbenes.
This issue of Neurosurgery Clinics, edited by Alejandro A. Rabinstein, will focus on Neurocritical Care. Topics will include Anoxic-Ischemic Brain Injury, Practical Approach to Posttraumatic Intracranial Hypertension According to Pathophysiologic Reasoning, Management of Traumatic Brain Injury: An Update, Cortical Spreading Depression and Ischemia in Neurocritical Patients, Targeted Temperature Management in Brain-Injured Patients, Herpes Virus Encephalitis in Adults: Current Knowledge and Old Myths, Primary Acute Neuromuscular Respiratory Failure, Intensive Care Unit–Acquired Weakness, Recent Advances in the Acute Management of Intracerebral Hemorrhage, New Developments in Refractory Status Epilepticus, Acute Cardiac Complications in Critical Brain Disease, Nosocomial Infections in the Neurointensive Care Unit, Neurologic Complications of Solid Organ Transplantation, and Shared Decision Making in Neurocritical Care.
At the age of twenty eight Gary was assaulted by a gang with baseball bats and a hammer, resulting in several skull fractures and severe brain damage. For nineteen months he had little awareness of his surroundings before he started to show some recovery. This inspirational book documents his exceptional journey. The book presents a series of interviews with Gary, his mother Wendie, who never gave up, the medical team who initially treated him, and the therapists who worked with him over a period of three years. Through their testimony we learn about the devastating effects which can follow a serious assault to the head, and the long process of recovery over several years. With specialist rehabilitation and continuing family support Gary has exceeded expectations and, apart from some minor physical problems, he is now a normal young man. Surviving Brain Damage after Assault shows that, contrary to popular belief, considerable gains can be made by people who have experienced a long period of reduced consciousness. The book will be of great value to all professionals working in rehabilitation - psychologists, speech and language therapists, occupational therapists, social workers and rehabilitation doctors, and to people who have sustained a brain injury and their families.
This book explores the connection of functional pain syndromes (e.g., irritable bowel syndrome and fibromyalgia) with anxiety, depression, chronic fatigue syndrome, and posttraumatic stress disorder. The authors address possible common pathophysiologies and review a range of treatment options, from antidepressants to cognitive-behavioral therapy. Who should buy this book? Whether you are a general practitioner, specialist, or scientist, this book is essential reading. It sheds new light on the complex links between various painful syndromes and disorders.
Offering today's most authoritative, comprehensive coverage of sleep disorders, Kryger's Principles and Practice of Sleep Medicine, 7th Edition, is a must-have resource for sleep medicine specialists, fellows, trainees, and technicians, as well as pulmonologists, neurologists, and other clinicians who see patients with sleep-related issues. It provides a solid understanding of underlying basic science as well as complete coverage of emerging advances in management and treatment for a widely diverse patient population. Evidence-based content, hundreds of full-color illustrations, and a wealth of additional resources online help you make well-informed clinical decisions and offer your patients the best possible care. - Contains new chapters on sleep in intersex and transgender individuals; sleep telemedicine and remote PAP adherence monitoring; and sleep and the menstrual cycle, as well as increased coverage of treatment and management of pediatric patients. - Includes expanded sections on pharmacology, sleep in individuals with other medical disorders, and methodology. - Discusses updated treatments for sleep apnea and advancements in CPAP therapy. - Offers access to 95 video clips online, including expert interviews and sleep study footage of various sleep disorders. - Meets the needs of practicing clinicians as well as those preparing for the sleep medicine fellowship examination or recertification exams, with more than 950 self-assessment questions, answers, and rationales online. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Get a firm handle on the engineering reliability process with this insightful and complete resource Named one of the Best Industrial Management eBooks of All Time by BookAuthority As featured on CNN, Forbes and Inc – BookAuthority identifies and rates the best books in the world, based on recommendations by thought leaders and experts The newly and thoroughly revised 3rd Edition of Reliability Engineering delivers a comprehensive and insightful analysis of this crucial field. Accomplished author, professor, and engineer, Elsayed. A. Elsayed includes new examples and end-of-chapter problems to illustrate concepts, new chapters on resilience and the physics of failure, revised chapters on reliability and hazard functions, and more case studies illustrating the approaches and methodologies described within. The book combines analyses of system reliability estimation for time independent and time dependent models with the construction of the likelihood function and its use in estimating the parameters of failure time distribution. It concludes by addressing the physics of failures, mechanical reliability, and system resilience, along with an explanation of how to ensure reliability objectives by providing preventive and scheduled maintenance and warranty policies. This new edition of Reliability Engineering covers a wide range of topics, including: Reliability and hazard functions, like the Weibull Model, the Exponential Model, the Gamma Model, and the Log-Logistic Model, among others System reliability evaluations, including parallel-series, series-parallel, and mixed parallel systems The concepts of time- and failure-dependent reliability within both repairable and non-repairable systems Parametric reliability models, including types of censoring, and the Exponential, Weibull, Lognormal, Gamma, Extreme Value, Half-Logistic, and Rayleigh Distributions Perfect for first-year graduate students in industrial and systems engineering, Reliability Engineering, 3rd Edition also belongs on the bookshelves of practicing professionals in research laboratories and defense industries. The book offers a practical and approachable treatment of a complex area, combining the most crucial foundational knowledge with necessary and advanced topics.
Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text covers the full range of obstetric and gynecologic pathology, including information on treatment and patient management. Written largely by the pathology and clinical faculty at Harvard's Brigham and Women's Hospital, it covers the most up-to-date information available in the field, including molecular genetics and diagnostics. Drs. Christopher P. Crum and Marisa R. Nucci are joined by new editors Scott R. Granter, Brooke E. Howitt, Mana M. Parast, and Theonia K. Boyd, to provide complete, beautifully illustrated coverage of both neoplastic and non-neoplastic disorders of the female genital system, ideal for improving pathological diagnosis. - Provides distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice. - Features more than 2,250 full-color images, key points at the end of each chapter, and an appendix with commonly used ICD-10 codes - Covers topics not often found in gynecologic pathology textbooks, such as vulvodynia, and diseases of the anus. - Approaches topics from a practice-oriented point of view, beginning with clinical presentation and progressing through histopathology, differential diagnosis, and treatment for each disorder. - Emphasizes new practice issues and their biologic basis including approaches to vulvar, cervical and endometrial precursors as well as the underpinnings of cervical, endometrial and ovarian cancer. - A comprehensive look at mesenchymal neoplasia, including not only lower genital tract and uterus but also the retroperitoneum. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Maritime travelers and tillers of the soil: reading the landscape(s) of Batur / Kaja McGowan -- More than a picture: the instrumental quality of the shadow puppet / Jan Mrz̀ek -- Modern Indonesian ceramic art / Hilda Soemantri -- Memories of a ceramic expert / Barbara Harrisson -- Lucia Hartini, Javanese painter: against the grain, towards herself / Astri Wright -- In the image of the king: two photographs from nineteenth-century Siam / Caverlee Cary -- Whose art are we studying? writing Vietnamese art history from colonialism to the present / Nora A. Taylor -- Telling lives: narrative allegory on a Burmese silver bowl / Robert S. Wicks -- Development of Buddhist traditions in peninsular Thailand: a study based on votive tablets (seventh to eleventh centuries) / M.L. Pattaratorn Chirapravati -- Chinese ceramics and local cultural statements in fourteenth-century southeast Asia / John N. Miksic -- Buddhism and the Pre-Islamic archaeology of Kutei in the Mahakam Valley of east Kalimantan / E. Edwards McKinnon.
“Development Without Aid” opens up perspectives about foreign aid to the world’s poorest countries. Growing up in Malawi the author developed a sense of the limitations of foreign assistance and from this evolves a critique of foreign aid as an alien resource unable to provide the dynamism that could propel the poorest countries out of poverty. The book aims to help move the discussion beyond foreign aid. It examines the rapid growth of the world’s diasporas as a quasi-indigenous resource of increasing strength in terms of both financial and human capital, and considers how far such a resource might supersede aid. It uses extensive research findings to explore the possibilities for a resumption of sovereignty by poor states, especially in Africa, over their own development with the assistance of the world’s diasporas.
South Asia, a region of outstanding biological diversity, is home to approximately 2.1 billion people whose rich cultural traditions include sophisticated knowledge of the properties and uses of thousands of native and introduced plant species. Plant-based drugs, integral to the traditional medical systems of India and neighboring countries, play a central role in health care throughout the region and beyond, as regional and global demand for therapeutically valuable plants continues to grow. However, the ongoing transformation and degradation of forests and other natural ecosystems in this region due to rapid environmental and socioeconomic changes, poses serious challenges for the conservation and sustainable utilization of its medicinal plant wealth. Efforts to conserve the region’s rich biodiversity and associated traditional knowledge require up-to-date information on the status and trends of these resources and their importance for health care and livelihoods. Healing Plants of South Asia: A Handbook of the Medicinal Flora of the Indian Subcontinent helps to address this need. The work’s introduction provides overviews of South Asia’s diverse systems of traditional medicine, as well as the region’s biogeography, ecosystem and plant species diversity and associated conservation challenges. Subsequent chapters focus on nearly 2,000 species of plants most commonly used in traditional medicine within the region. In chapters devoted to ferns and lycophytes (including 59 species), conifers (20 species) and flowering plants (1849 species), the information provided draws upon a wide variety of authoritative published sources as well as reliable online databases. Entries for each species include: currently accepted scientific names and common synonyms; vernacular names in the major regional languages; a complete botanical description; information on the species’ ecology and conservation status; traditional therapeutic uses in Ayurveda, Unani, Siddha, Tibetan medicine, and more localized folk medical systems; and key references. The majority of these species are also beautifully illustrated with photos and/or botanical drawings. Healing Plants of South Asia: A Handbook of the Medicinal Flora of the Indian Subcontinent will be of value to students, scientists and professionals in a number of fields, including pharmacology, pharmaceutics, food chemistry and nutrition, natural products chemistry, ethnobotany and ethnomedicine. It should also appeal to conservationists, community development practitioners, industry, and policy makers, among a host of those involved in the world of medicinal plants and traditional medicine in South Asia.
Heart disease and strokes are currently the leading cause of death in all developed countries and in most developing countries, resulting in one third of all deaths globally in 2003. This publication explores a range of issues relating to this increasingly urgent global health problem using text, colour charts, maps and graphics. Topics covered include: different types of cardiovascular diseases, including rheumatic heart disease; key risk factors including smoking, obesity, physical inactivity, high cholesterol levels and diabetes; risks factors relating to women, childhood and youth; the global burden of coronary heart disease and stroke, and associated economic costs; medical research and funding issues; prevention in personal and public health terms; treatment options; health education; national policies and legislation to address prevention and control; future predictions; chronology of key developments in knowledge of cardiovascular disease; and world data tables.
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