Things aren’t easy right now for Marvin Pickering. He’s twelve years old, just beginning to really discover who he is…and he’s realizing that his feelings for his childhood friend, Ellen Peterson, are deeper and more complex than he knew. He could really use the guidance and understanding of his beloved father, Jay, but he’s serving his country in Viet Nam. When Marvin and his mother get the news that Jay is missing in action, the foundation of Marvin’s world is shattered. Instead of turning to family and friends, he runs away to his favorite retreat, the Big Woods. There, imaginative Marvin will have the adventure of a lifetime, as he meets his guardian angel, John, who takes him to see his father. Marvin will learn a valuable lesson about faith and trust, while those back home are left to look for him…with unexpected consequences that will teach Marvin even more about what’s really important. A vivid snapshot of a turning point in American history, a thrilling adventure, and a tender story about different kinds of love, The Adventures of Marvin Pickering: The Miracle at Weston Falls is a book with a positive message for young adult readers.
Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.
A powerful new kind of competitive advantage is now possible thanks to technological and social disruptions that are already occurring. These disruptions revolutionize how companies can partner to create new growth. The Reciprocity Advantage shares a model for creating that growth: define your right-of-way (the underutilized resources you already own that you can share with others), partner to do what you can’t do alone, experiment to learn, and scale the new business at low risk. Reciprocity and advantage are words that are not normally seen together, but reciprocity—giving now to get later—will become a normal part of winning in the future. The Reciprocity Advantage shows you how to leverage new forces like digital natives and cloud-served supercomputing now into massively scalable, profitable, incremental growth for your business. Provocative and pragmatic, leading ten-year forecaster Bob Johansen and experienced business developer Karl Ronn describe how to lean in to disruptions to create new growth for your business. They include actual cases showing early successes for a range of companies and nonprofits like IBM, Microsoft, Google, Apple, and TED. They then provide key exercises to define your promising new ideas and nurture them into healthy new businesses. Their recommendations are based on practical experience in managing the problems of new business creation and many years of helping others see the future more clearly. Distilled from hands-on work, this book gets you started today on creating your own reciprocity advantage.
3 remarkable books reveal the latest scientific discoveries about addiction, antibiotic-resistant disease, bacteria — and you These three remarkable books take you to the cutting edge of health science, revealing today’s most powerful scientific discoveries about addiction, antibiotic-resistant disease, and bacteria. In The Addicted Brain, leading neuroscientist Michael Kuhar, Ph.D. explains how and why addiction destroys lives, and presents the latest advances in treatment and prevention. Using breathtaking brain imagery and other research, Kuhar reveals the powerful, long-term brain changes that drugs can cause, explaining why it can be so difficult for addicts to escape them. He describes why some people are unusually susceptible to addiction; illuminates striking neural similarities between drugs and pleasures ranging from alcohol and gambling to sex and caffeine; and outlines the 12 characteristics most often associated with successful treatment. Next, in Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? Are there better ways to discover new antibiotics? How can we strengthen our defenses against resistance, minimize public health risks and extend the effectiveness of the antibiotics we have? Finally, in Allies and Enemies, Anne Maczulak tells the story of the amazing, intimate partnership between humans and bacteria. Offering a powerful new perspective on Earth’s oldest creatures, Maczulak explains how bacteria work, how they evolve, their surprising contributions and uses, the roles they’ve played in human history – and why you can't survive without them. From pioneering scientists and researchers including Michael Kuhar, Karl S. Drlica, David S. Perlin, and Anne Maczulak
3 books illuminate the cutting edge medical research that could save your life Right now, science is transforming what we know about preserving and improving human health. These three extraordinary books take you to the cutting edge of emerging science, presenting new findings that might someday save your life. In Antibiotic Resistance: Understanding and Responding to an Emerging Crisis, Karl S. Drlica and David S. Perlin presents a thorough and authoritative overview of the growing resistance of pathogenic bacteria to antibiotics, and what this means to our ability to control and treat infectious diseases. The authors answer crucial questions such as: What is resistance? How does it emerge? How do common human activities promote resistance? What can we do about it? How can we strengthen our defenses against resistance, minimize our risks, extend the effectiveness of current antibiotics, and find new ones faster? Next, in Chips, Clones, and Living Beyond 100: How Far Will the Biosciences Take Us?, Paul and Joyce A. Schoemaker tour the remarkable field of biosciences as it stands today, and preview the directions and innovations that are most likely to emerge in the coming years. They offer a clear, non-technical overview of crucial current developments that are likely to have enormous impact, addressing issues ranging from increased human longevity to global warming, bio-warfare to personalized medicine. Along the way, they illuminate each of the exciting technologies and hot-button issues associated with contemporary biotechnology - including stem cells, cloning, probiotics, DNA microarrays, proteomics, gene therapy, and more. Finally, in It Takes a Genome, Greg Gibson posits a revolutionary new hypothesis: our genome is out of equilibrium, both with itself and its environment. Our bodies weren’t designed to subsist on fat and sugary foods; our immune systems aren’t designed for today’s clean, bland environments; our minds aren’t designed to process hard-edged, artificial electronic inputs from dawn ‘til midnight. That, says Gibson, is why so many of us suffer from chronic diseases that barely touched our ancestors. Gibson reveals the stunningly complex ways genes cooperate and interact; illuminates the genetic “mismatches” that lead to cancer, diabetes, inflammatory and infectious diseases, AIDS, depression, and senility; and considers surprising new evidence for genetic variations in human psychology. From world-renowned leaders and experts, including Karl S. Drlica, David S. Perlin, Paul J. H. Schoemaker, Joyce A. Schoemaker, and Greg Gibson
A team of U.S. and international experts assesses the impact of various nations’ airpower efforts during the 2011 conflict in Libya, including NATO allies and non-NATO partners, and how their experiences offer guidance for future conflicts. In addition to the roles played by the United States, Britain and France, it examines the efforts of Italy, Canada, Belgium, Denmark, the Netherlands, Norway, Sweden, Qatar, the UAE, and the Libyan rebels.
This is the eBook version of the printed book. This Element is an excerpt from Antibiotic Resistance: Understanding and Responding to an Emerging Crisis (9780131387737) by Karl Drlica and David S. Perlin. Available in print and digital formats. The truth behind the headlines: What antibiotic resistance is, why it’s growing, and what this means to human health. As a global community, we have not considered antibiotics as a resource to be actively protected. Consequently, we use antibiotics in ways that directly lead to resistance. Changing those ways requires an understanding of antibiotic principles. We begin with a brief description of MRSA to illustrate a bacterial-based health problem....
A.G. STANSFELD, and J.A.M. VAN UNNIK. In joint discussions in 1974, the Club worked out a new terminology that was acceptable to all members and will hopefully be acceptable to other pathologists. Since then, it has been called the Kiel Classification. We are also pleased that the clinicians belonging to the Kiel Lymphoma Study Group-foremost A. STACHER and G. BRITTINGER have been able to present preliminary data on the clinical relevance of the new classification. Finally, our optimism was fortified by the findings of R.J. LUKES and R.D. COLLINS, which largely concur with ours in both concept and practical significance. This book is divided into six main sections. First, there is a chapter on normal cytology that supplements and, in some respects, revises the presentation given in Part A of this Handbook (1961). H.K. MULLER-HERMELINK played a major role in the writing of the first chapter. The second chapter is a brief description of the light-microscopic techniques that are used in our laboratories and have proved to be suitable for a precise diagnosis of lymph-node diseases.
The aim of present-day treatment of hypertension is no longer as the effective reduction of blood pressure, regarded merely but as the ever-increasing application of new therapeutic prin ciples to prevent such consequences of hypertension as left heart hypertrophy, medial hypertrophy of the vessels and ar teriosclerosis. In this context special attention has been di rected to stimulation of the endogenous vasocilator hormonal systems such as the prostaglandins. The great interest in our book, which has meanwhile appeared in a French edition, seems to confirm this trend and has encouraged us to include in the book the new findings published in the last twelve months. These changes and additions maintain the current status of the book and provide an even more complete survey of the available information about prostacyclin in hyperten sion. We wish to thank all those colleagues who have made useful suggestions for this second edition, as well as Springer Verlag and its associates, who ensured a uniformly smooth passage in the production of the book. Cologne and MUnster, January 1990 Gerd Bonner Karl-Heinz Rahn v Preface to the First Edition Diseases of the heart and circulation currently constitute the commonest causes of death in our population. Hypertension, as evidenced by a pathologic increase in blood pressure, is one of the most important risk factors. Primary hypertension can be established in about 15 % of adults. Patients with hyperten sion usually feel well subjectively and only rarely complain of symptoms.
Overcome the toughest clinical challenges in nephrology with Brenner & Rector’s The Kidney -- the most well-known nephrology resource in the world. A diverse team of more than 200 international contributors brings you the latest knowledge and best practices on every front in nephrology worldwide. From basic science and pathophysiology to clinical best practices, Brenner & Rector’s The Kidney is your go-to resource for any stage of your career. Review of the basic science that underpins clinical nephrology, comprehensive selection of the most important bibliographical sources in nephrology, and Board Review-style questions help you prepare for certification or recertification. Coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and into old age. Expanded sections and chapter on global perspective and ethical considerations. Uniform terminology and nomenclature in line with emerging consensus in world kidney community. More than 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making provide a visual grasp and better understanding of critical information. Internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors . An editorial team headed by Dr. Skorecki and handpicked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. All chapters have been extensively updated or entirely rewritten by authorities in their respective fields. The latest clinical information including recent clinical trials, genetic causes of kidney disease, cardiovascular and renal risk prediction in chronic kidney disease, new paradigms in fluid and electrolyte management, and pediatric kidney disease, keep you current with the rapid development of care and research worldwide.
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