The present book is the fruit of a workshop, designed as a discussion forum, with the participation of experts from all over the world, to extensively review clinical, neurophysiological and fundamental research available data in order to generate new axes for research, clinical practice and care. The first section traces back to the definitions and concepts underlying the terms “generalized seizures and epilepsies”. Section II reviews human and animal data suggesting that the brainstem network plays an important role for tonic seizures generation. The third and fourth sections analyze recent knowledge on cortico-thalamic and basal ganglia networks in absence and myoclonic seizures, both in animal models and in humans. The fifth section compares the phenomenology of “Primary versus Secondary Tonico-clonic seizures”, including animal data, clinical expression in humans and genetics. Section VI goes back to the discussion “Cortical” versus “Centrencephalic” theories. The last two chapters thoroughly review the clinical applications of current knowledge, in terms of pharmacological approach and clinical care.
Edouard Roditi's critical study of Oscar Wilde, originally published in 1947 in New Directions' Makers of Modern Literature Series, was a pioneering attempt to evaluate a literary reputation long distorted by the journalistic appetite for scandal. Relegating biography to a back seat, Roditi addressed the important of Wilde's ingenious, imaginative, and dialectical thought in his own time and showed how his poetry, novels, plays, and critical writings were a key influence in the shift of English and American literature away from established and aging Romanticism toward Modernism. For this first paperbound edition of his perceptive and erudite study of Wilde, Roditi has added three additional chapters touching on new material about Wilde as well as the new public attitudes about homosexuality that have evolved since the book was first published. An American long resident in Paris, Edouard Roditi is an internationally known linguist, scholar, art critic, and author and translator of a considerable number of works of fiction and poetry, criticism and biography. A collection of his witty and exotic short stories, The Delights of Turkey, is available under the New Directions imprint.
In spite of progress in biomedical research, we know little about the causes, prevention, and treatment of the numerous mental and neurological disorders that afflict up to 15% of all individuals. In the last decade, great advances have been made in the physiopathology of mental and neurological disorders, leading to at least a partial control of Parkinson's disease, epilepsy, certain psychoses, and anxiety syndromes. Despite the fact that an underlying specific neurotransmitter deficiency has been demonstrated in Alzheimer's and Parkinson's diseases, the immune dysfunction and viral hypotheses continue to be attractive for investigators dealing with these degenerative diseases of the aging brain, which afflict 10% of senior citizens. A retrospective epidemiologic study suggests that the encephalitis lethargica and parkinsonism were almost certainly caused by the 1918 influenza virus pandemics. It must be stressed that the etiopathogenesis of many mental disorders is not known, and this ignorance has led to several untenable neurophysiological and biochemical hypotheses. Epidemiologic investigations show a high prevalence of functional psychoses and organic mental disorders. Although many of them are conceptualized as biopsychosocial disorders, recent data indicate that the biological component appears more and more as a major etiologic factor. Among the various biological hypotheses, the viral and im munologic concept has become a significant one. In view of recent discoveries in virology and immunity, it becomes clear that viral and immunologic hypotheses should be inves tigated more systematically concerning the mechanisms of numerous mental and neu rological disorders.
This bracing new nonfiction book by the young superstar E´douard Louis is both a searing j’accuse of the viciously entrenched French class system and a wrenchingly tender love letter to his father This bracing new nonfiction book by the young superstar Édouard Louis is both a searing j’accuse of the viciously entrenched French class system and a wrenchingly tender love letter to his father. Who Killed My Father rips into France’s long neglect of the working class and its overt contempt for the poor, accusing the complacent French—at the minimum—of negligent homicide. The author goes to visit the ugly gray town of his childhood to see his dying father, barely fifty years old, who can hardly walk or breathe:“You belong to the category of humans whom politics consigns to an early death.” It’s as simple as that. But hand in hand with searing, specific denunciations are tender passages of a love between father and son, once damaged by shame, poverty and homophobia. Yet tenderness reconciles them, even as the state is killing off his father. Louis goes after the French system with bare knuckles but turns to his long-alienated father with open arms: this passionate combination makes Who Killed My Father a heartbreaking book.
Manet, a founding father of modernism, is one of the towering figures of 19th-century art. In this volume, Carol Armstrong looks closely at Manet's works to uncover a view not only of the artist but also of modernity itself. As she places his art within frameworks of colour, the feminine Other (the Manette in Manet), and consumerism, Armstrong seeks to expand and revise our understanding of this artist as a painter of modern life.
Edouard Vuillard (1868-1940), one of the most admired post-impressionist artists, is best-known for his small easel paintings and their charming portrayals of everyday life. However, a major part of his work during his early life was the painting of large decorative panels in the Parisian homes of wealthy private patrons, produced between 1892 and 1912. These panels - some fifty in total - have been little studied, due principally to the inaccessibility of many of them and the impossibility of their being included in exhibitions.
Théodore Rousseau (1812–1867), arguably the most important French landscape artist of the mid-nineteenth century and a leader of the so-called Barbizon School, occupies a crucial moment of transition from the idealizing effects of academic painting to the radically modern vision of the Impressionists. He was an experimental artist who rejected the traditional historical, biblical, or literary subject matter in favor of “unruly nature,” a Romantic naturalism that confounded his contemporaries with its “bizarre” compositional and coloristic innovations. Lavishly illustrated and thoroughly documented, this volume includes five essays by experts in the field. Scott Allan and Édouard Kopp alternately examine Rousseau’s diverse techniques and working procedures as a painter and as a draftsman, as well as his art’s mixed economic and critical fortunes on the art market and at the Salon. Line Clausen Pedersen’s essay focuses on Mont Blanc Seen from La Faucille, Storm Effect, an early touchstone for the artist and a spectacular example of the Romantic sublime in the Ny Carlsberg Glyptotek’s collection. This catalogue accompanies an eponymous exhibition on view at the J. Paul Getty Museum from June 21 to September 11, 2016, and at the Ny Carlsberg Glyptotek from October 13, 2016, to January 8, 2017.
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