General, Organic and Biological Chemistry, 4th Edition has been written for students preparing for careers in health-related fields such as nursing, dental hygiene, nutrition, medical technology and occupational therapy. It is also suited for students majoring in other fields where it is important to have an understanding of the basics of chemistry. An integrated approach is employed in which related general chemistry, organic chemistry, and biochemistry topics are presented in adjacent chapters. This approach helps students see the strong connections that exist between these three branches of chemistry, and allows instructors to discuss these, interrelationships while the material is still fresh in students' minds.
All space was electrified as that harsh challenge rang out ... but John Endlich hesitated. For he saw beyond his own murder - saw the horror and destruction his death would unleash - and knew he dared not fight back!
This monograph provides an up-to-date discussion of analysis strategies for regression problems in which predictor variables are measured with errors. The analysis of nonlinear regression models includes generalized linear models, transform-both-sides models and quasilikelihood and variance function problems. The text concentrates on the general ideas and strategies of estimation and inference rather than being concerned with a specific problem. Measurement error occurs in many fields, such as biometry, epidemiology and economics. In particular, the book contains a large number of epidemiological examples. An outline of strategies for handling progressively more difficult problems is also provided.
This is a deep and beautiful monograph in functional analysis, at the interface with mathematical physics.'Mathematical ReviewsThe integration of vector valued functions with respect to vector valued measures, especially spectral measures, is developed in view of applications in operator theory, scattering theory and semiclassical approximation in quantum physics. New techniques are developed for bilinear integration in cases where the classical approach does not apply.
Biochemistry is a single-semester text designed for undergraduate non-biochemistry majors. Accessible, engaging, and informative, Biochemistry is the perfect introduction to the subject for students who may approach chemistry with apprehension. Biochemistry's unique emphasis on metabolism and its kinetic underpinnings gives the text up-to-the-minute relevance for students investigating current public health concerns such as obesity and diabetes. Biochemistry will encourage students to explore the basics of chemistry and its influence on biological problems.Biochemistry provides students with a broad understanding of contemporary advances in molecular biology. Its innovative approach will challenge students to develop connections across multiple concepts, and sets Biochemistry apart in a crowded field. Biochemistry is an invaluable and user-friendly resource.This innovative text for non-biochemistry majors includes:* Introductory material at the beginning of each chapter that contextualizes chapter themes in real-life scenarios* Clear list of objectives for each chapter* Online supporting materials with further opportunities for research and investigation* Synthesis questions at the end of each chapter that encourage students to make connections between concepts and ideas, as well as develop critical-thinking skills
Notoriously cumbersome to isolate and challenging to synthesize, the path of natural products to viable drugs is an arduous journey. Yet compounds isolated from nature may possess fascinating structures, biological profiles and pharmaceutical potential far greater than anything made by man. Natural Products Chemistry: Sources, Separations and Structures presents a practical guide to sourcing, isolating, and discovering new compounds from nature many of which become pharmaceutical drugs. This book emphasizes the challenges and advantages of products acquired from nature, compared to those obtained from combinatorial chemistry. A basic introduction, the book describes the whole cycle from farm to final compound, backed up by case studies drawn from industry and research applications. It broadens the scope of applications and draws upon examples from various sources. Natural products chemistry, as taught today, draws its examples mainly from marine chemistry or plant chemistry; however, there is also a fascinating and rich world of fermented (microbial and algal) products leading to complex structures. Thus, the book draws upon examples from the microbial world and from insects too. Therefore, this is a source of bioactive metabolites, not traditionally available in academic settings, more the mainstay of the pharmaceutical industry. Providing a roadmap of the process of collecting a compound from nature, isolating the active ingredient, and determining the chemical structure, this book provides a unique approach to the world of natural products.
Designed as both a textbook for advanced engineering students and a reference book for practicing engineers, this highly regarded work deals not only with the practical aspects of aeroelasticity, but the aerodynamic and structural tools upon which these rest. Accordingly, the book divides roughly into two halves: the first deals with the tools and the second with applications of the tools to aeroelastic phenomena. Topics include deformation of airplane structures under static and dynamic loads, approximate methods of computing natural mode shapes and frequencies, two-and three-dimensional incompressible flow, compressible flow, wings and bodies in three-dimensional unsteady flow, static aeroelastic phenomena, flutter, dynamic response phenomena, aeroelastic model theory, model design and construction, testing techniques and more. Chapters have been designed to progress from easy to difficult so that instructors using this book as an elementary text in aeroelasticity will find their purposes served by simply using the first parts of selected chapters. Helpful appendixes deal with such mathematical tools as matrices and linear systems (prerequisites include the usual engineering mathematics courses and advanced calculus), while many numerical examples are included throughout the text. Engineering students as well as practicing engineers will find this work an unmatched treatment of the topic and an indispensable reference for their libraries.
This book is an evolution from my book A First Course in Information Theory published in 2002 when network coding was still at its infancy. The last few years have witnessed the rapid development of network coding into a research ?eld of its own in information science. With its root in infor- tion theory, network coding has not only brought about a paradigm shift in network communications at large, but also had signi?cant in?uence on such speci?c research ?elds as coding theory, networking, switching, wireless c- munications,distributeddatastorage,cryptography,andoptimizationtheory. While new applications of network coding keep emerging, the fundamental - sults that lay the foundation of the subject are more or less mature. One of the main goals of this book therefore is to present these results in a unifying and coherent manner. While the previous book focused only on information theory for discrete random variables, the current book contains two new chapters on information theory for continuous random variables, namely the chapter on di?erential entropy and the chapter on continuous-valued channels. With these topics included, the book becomes more comprehensive and is more suitable to be used as a textbook for a course in an electrical engineering department.
Photodynamic therapy (PDT) is a ground breaking medical technique which uses lasers to activate light-sensitive chemicals to treat cancer and other diseases without resorting to surgery. For the first time, Chemical Aspects of Photodynamic Therapy introduces in an accessible way the physics, chemistry and biology behind the technique. This highly authoritative account of the account of the rapidly developing field of PDT explores its chemical basis, while presenting information in its historical context. Haematoporphyrin derivative is considered in detail, together with the new 'second generation' photosensitisers , such as chlorins, bacteriochlorins and phthalocyanines. Photosensitisers which are currently in clinical trials are compared and reference is made to new light sources, biological and clinical findings, and prospects for future developments. This book is essential reading for new students and researchers alike studying PDT. It is recommended particularly for photochemists, as well as photobiologists and clinicians. About the author Raymond Bonnett was born in London in 1931. After a spell in the air force, he graduated from Imperial College, going on to Cambridge to research under Alexander Todd and A.W. Johnson and then to Harvard to work with R.B. Woodward. He is now Scotia Research Professor of Chemistry at Queen Mary and Wesfield College, University of London, UK. He has been active in research on photosensitisers for 25 years and has published over 200 papers on the chemistry of porphyrins and related compounds.
This book develops the theoretical and experimental basis of quantum optics, i.e. the interaction of individual particles of light (photons) with matter, starting from elementary quantum theory. The self-contained exposition will be useful to graduate students in physics, engineering, chemistry, and senior undergraduates in physics.
By 1914 France had amassed over ten million square kilometres, and 60 million people including the colonies of Algeria, Tunisia, Morocco, the colony in S.E. Asia known as Indochina and a vast block of West Africa. This study gives the undergraduate student a factual geographical and historical background to the establishment of the early twentieth century French colonial empire. The author describes in detail the physical struggles between the colonies and their rules and the subsequent demise of the Empire.
A thorough understanding of biology, no matter which subfield, requires a thorough understanding of statistics. As in previous editions, Havel and Hampton (with new co-author Scott Meiners) ground students in all essential methods of descriptive and inferential statistics, using examples from different biological sciences. The authors have retained the readable, accessible writing style popular with both students and instructors. Pedagogical improvements new to this edition include concept checks in all chapters to assist students in active learning and code samples showing how to solve many of the book's examples using R. Each chapter features numerous practice and homework exercises, with larger data sets available for download at waveland.com.
A selection of topics which graduate students have found to be a successful introduction to the field, employing three distinct techniques: geometric topology manoeuvres, combinatorics, and algebraic topology. Each topic is developed until significant results are achieved and each chapter ends with exercises and brief accounts of the latest research. What may reasonably be referred to as knot theory has expanded enormously over the last decade and, while the author describes important discoveries throughout the twentieth century, the latest discoveries such as quantum invariants of 3-manifolds as well as generalisations and applications of the Jones polynomial are also included, presented in an easily intelligible style. Readers are assumed to have knowledge of the basic ideas of the fundamental group and simple homology theory, although explanations throughout the text are numerous and well-done. Written by an internationally known expert in the field, this will appeal to graduate students, mathematicians and physicists with a mathematical background wishing to gain new insights in this area.
Peking, winter 1948. Encircled by Mao's Communist armies, Nationalist warlord Fu Tsoyi seeks the solution to saving Peking in his Taoist concubine's lessons in calligraphy and passion. Chief Inspector Bei wrestles with a string of brutal courtesan murders, slowly realizing with horror that the solution to the murders is tied to saving his beloved Peking, and China's emergence into the modern world.
This book provides an explanation of electromagnetic scattering effects in the intergalactic medium that produce what have been misinterpreted as 'evolutionary' effects. It accounts for a variety of cosmological phenomena from spectroscopic redshifts to microwave background radiation. These have variously been attributed by the standard cosmological model to an origin in a 'big bang', 'dark matter', and mysterious 'vacuum energy'. This scattering model provides a viable stationary state alternative to the established view of the universe with predictions that more precisely match observation without ad hoc assumptions.
Differential and complex geometry are two central areas of mathematics with a long and intertwined history. This book, the first to provide a unified historical perspective of both subjects, explores their origins and developments from the sixteenth to the twentieth century. Providing a detailed examination of the seminal contributions to differential and complex geometry up to the twentieth-century embedding theorems, this monograph includes valuable excerpts from the original documents, including works of Descartes, Fermat, Newton, Euler, Huygens, Gauss, Riemann, Abel, and Nash. Suitable for beginning graduate students interested in differential, algebraic or complex geometry, this book will also appeal to more experienced readers.
This research monograph provides systematic and comprehensive materials for applying inframarginal analysis to study a wide range of economic phenomena. The analysis is based on a new overarching framework to resurrect the classical notion of division of labor and specialization, which is an essential source of increasing a nation's wealth. The framework absorbs many classical and neo-classical insights in a general equilibrium analysis and explains many micro- and macro-phenomena. Many areas of the discipline that have been customarily treated as separate branches can now be analyzed systematically within this integrated framework. These include, for example, micro-economics; macro-economics; development economics; international economics; urban economics; growth theory; industrial organization; applications of game theory in economics; economics of property rights; economics of transaction costs; economics of institutions and contract; economics of organization; economics of states; managerial economics; theory of hierarchy; new theory of the firm; theory of money; theory of insurance; theory of network and reliability.
This book discusses an efficient random linear network coding scheme, called BATched Sparse code, or BATS code, which is proposed for communication through multi-hop networks with packet loss. Multi-hop wireless networks have applications in the Internet of Things (IoT), space, and under-water network communications, where the packet loss rate per network link is high, and feedbacks have long delays and are unreliable. Traditional schemes like retransmission and fountain codes are not sufficient to resolve the packet loss so that the existing communication solutions for multi-hop wireless networks have either long delay or low throughput when the network length is longer than a few hops. These issues can be resolved by employing network coding in the network, but the high computational and storage costs of such schemes prohibit their implementation in many devices, in particular, IoT devices that typically have low computational power and very limited storage. A BATS code consists of an outer code and an inner code. As a matrix generalization of a fountain code, the outer code generates a potentially unlimited number of batches, each of which consists of a certain number (called the batch size) of coded packets. The inner code comprises (random) linear network coding at the intermediate network nodes, which is applied on packets belonging to the same batch. When the batch size is 1, the outer code reduces to an LT code (or Raptor code if precode is applied), and network coding of the batches reduces to packet forwarding. BATS codes preserve the salient features of fountain codes, in particular, their rateless property and low encoding/decoding complexity. BATS codes also achieve the throughput gain of random linear network coding. This book focuses on the fundamental features and performance analysis of BATS codes, and includes some guidelines and examples on how to design a network protocol using BATS codes.
The most respected nutrition text for more than 50 years, Krause's Food & the Nutrition Care Process delivers comprehensive and up-to-date information from respected educators and practitioners in the field. The latest recommendations of the Dietary Guidelines for Americans 2010, new and expanded chapters, and a large variety of tables, boxes, and pathophysiology algorithms provide need-to-know information with ease, making this text perfect for use in class or everyday practice. Clear, logical organization details each step of complete nutritional care from assessment to therapy. UNIQUE! Pathophysiology algorithms clarify the illness process and to ensure more effective care. New Directions boxes reflect the latest research in emerging areas in nutrition therapy. Focus On boxes provide additional detail on key chapter concepts. Clinical Insight boxes and Clinical Scenarios with detailed Sample Nutrition Diagnosis statements help ensure the most accurate and effective interventions in practice. Key terms listed at the beginning of each chapter and bolded within the text provide quick access to important nutrition terminology. More than 1,000 self-assessment questions on a companion Evolve website reinforce key textbook content. Reorganized table of contents reinforces the Nutrition Care Process structure endorsed by the American Dietetic Association (ADA). New recommendations reflect a comprehensive approach to diet and nutrition that incorporates the Dietary Guidelines for Americans 2010, the MyPyramid food guide, and the Eating Well with Canada's Food Guide recommendations. MNT for Thyroid Disorders chapter details important nutrition considerations for managing thyroid disorders. New calcium and vitamin D Dietary Recommended Intakes (DRIs) improve monitoring of nutrient intake. Expanded Nutrition in Aging chapter includes assessment and nutritional care guidelines for the growing elderly patient population. Growth grids for children detail proper patient nutrition during infancy and early childhood. Extensively revised MNT for Food Allergies chapter highlights the importance of food allergy management in clinical nutrition therapy. Updated appendices enhance assessment accuracy with the latest laboratory findings and normal values.
The Organic Chemistry of Museum Objects' makes available in a single volume, a survey of the chemical composition, properties and analysis of the whole range of organic materials incorporated into objects and artworks found in museum collections. The authors cover the fundamental chemistry of the bulk materials such as wood, paper, natural fibres and skin products, as well as that of the relatively minor components incorporated as paint, media, varnishes, adhesives and dyes. This expanded second edition, now in paperback, follows the structure of the first, though it has been extensively updated. In addition to chapters on basic organic chemistry, analytical methods, analytical findings and fundamental aspects of deterioration, the subject matter is grouped as far as possible by broad chemical class - oils and fats, waxes, bitumens, carbohydrates, proteins, natural resins, dyestuffs and synthetic polymers. This is an essential purchase for all practising and student conservators, restorers, museum scientists, curators and organic chemists.
Addressing the immensely important topic of research credibility, Raymond Hubbard’s groundbreaking Corrupt Research proposes that we must treat such information with a healthy dose of skepticism. This book argues that the dominant model of knowledge procurement subscribed to in these areas—the significant difference paradigm—is philosophically suspect, methodologically impaired, and statistically broken. Hubbard introduces a more accurate, alternative framework—the significant sameness paradigm—for developing scientific knowledge. The majority of the book comprises a head-to-head comparison of the “significant difference” versus “significant sameness” conceptions of science across philosophical, methodological, and statistical perspectives.
In the 19th century, the Fourier transformation was introduced to study various problems of partial differential equations. Since 1960, this old tool has been developed into a well-organized theory called microlocal analysis that is based on the concept of the pseudo-differential operator. This book provides the fundamental knowledge non-specialists need in order to use microlocal analysis. It is strictly mathematical in the sense that it contains precise definitions, statements of theorems and complete proofs, and follows the usual method of pure mathematics. The book explains the origin of the theory (i.e., Fourier transformation), presents an elementary construcion of distribution theory, and features a careful exposition of standard pseudodifferential theory. Exercises, historical notes, and bibliographical references are included to round out this essential book for mathematics students; engineers, physicists, and mathematicians who use partial differential equations; and advanced mathematics instructors.
In this pathbreaking book, one of Britain s most eloquent and original thinkers writes about the head, what happens in it, and how it is and is not connected to our sense of identity and consciousness. Blending science, philosophy, and humor, Raymond Tallis examines the extraordinarily complex relationship we have with our heads. His aim, as he says, is to turn readers into astonished tourists of the piece of the world that is closest to them, so they never again take for granted the head that looks at them from the mirror. Readers will delight that this is precisely what he accomplishes. The voyage begins with a meditation on the self-portrait of a mirror image, followed by a consideration of the head s various secretions. Tallis contemplates the air we exhale; the subtle meanings of nods, winks, and smiles; the mysteries of hearing, taste, and smell. He discusses the metaphysics of the gaze, the meaning of kissing, and the processes by which the head comes to understand the world. Along the way he offers intriguing digressions on such notions as having and using one s head, and enjoying and suffering it. Tallis concludes with his thoughts on the very thing the reader s head has been doing throughout the book: thinking.
This book, with the CD-ROM included, is the documentation of a unique collaborative effort in evaluating formal methods for usage under industrial constraints: the major techniques for formally supported specification, design, and verification of large programs and complex systems are applied to a non-trivial and non-academic problem which is typical for industrial informal requirements specifications. The 21 papers included in the book, together with an introduction and competition report, were selected from 33 candidate solutions. This book comes with a CD-ROM containing, besides the printed papers, executable code, full definitions of all parts of the specifications, and detailed descriptions of foundational matters where appropriate.
Quantum many-body theory as a discipline in its own right dates largely from the 1950's. It has developed since then to its current position as one of the cornerstones of modern theoretical physics. The field remains vibrant and active, vigorous and exciting. Its most powerful techniques are truly universal. They are constantly expanding to find new fields of application, while advances continue to be made in the more traditional areas. To commemorate the impending 80th birthdays of its two co-inventors, Firtz Coester and Hermann Kummel, one such technique, namely the coupled cluster method, was especially highlighted at this meeting, the eleventh in the series of International Conferences on Recent Progress in Many-Body Theories. The history of the coupled cluster method as told here mirrors in many ways both the development of the entire discipline of microscopic quantum many-body theory and the history of the series of conferences. The series itself is universally recognised as being the premier series of meetings in this subject area. Its proceedings have always summarised the current state of the art through the lectures of its leading practitioners. The present volume is no exception. No serious researcher in quantum many-body theory or in any field which uses it can afford to be without this volume.
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